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Protocol No.
UW16064
Principal Investigator
Harari, Paul
Phase
N/A
Age Group
Adult
Scope
Local
Sponsor Type
Institutional
Title
PET/MRI to Enhance Precision Guidance in Head and Neck Radiation Treatment Planning
Objective
The purpose of this imaging study is to investigate if scans from a new technology, a combined PET/MRI scanner, can help us better see and design radiation treatment plans for head and neck cancer when compared to our current treatment planning methods which use PET/CT images. A CT scan combines many x-rays together to provide the CT portion of the scan which is really good at looking at bones. MRI's use radiowaves and are really good at looking at soft tissue. When an MRI is obtained the radiowaves create "pulse sequences". Numerous different pulse sequences are used to create MRI images. In this study we will be trying to find the pulse sequences that help us view the head and neck area best.
Both PET/CT and PET/MRI scans and their contrast/radioactive isotopes used in this study are FDA approved. In addition to acquiring FDA approved MRI pulse sequences we will use some investigational pulse sequences and compare them to the FDA approved sequences. Only images acquired from FDA sequences will be used to plan your radiation treatment
The purpose of this imaging study is to investigate if scans from a new technology, a combined PET/MRI scanner, can help us better see and design radiation treatment plans for head and neck cancer when compared to our current treatment planning methods which use PET/CT images. A CT scan combines many x-rays together to provide the CT portion of the scan which is really good at looking at bones. MRI's use radiowaves and are really good at looking at soft tissue. When an MRI is obtained the radiowaves create "pulse sequences". Numerous different pulse sequences are used to create MRI images. In this study we will be trying to find the pulse sequences that help us view the head and neck area best.
Both PET/CT and PET/MRI scans and their contrast/radioactive isotopes used in this study are FDA approved. In addition to acquiring FDA approved MRI pulse sequences we will use some investigational pulse sequences and compare them to the FDA approved sequences. Only images acquired from FDA sequences will be used to plan your radiation treatment
Treatment
PET/MRI to Enhance Precision Guidance in Head and Neck Treatment Planning
Description
This is a pilot study designed to assess the impact of hybrid PET/MRI imaging on the gross target volume definition for radiotherapy planning
Key Eligibility
Tumors of the head and neck region (nasal cavity, oral cavity, pharynx, larynx, sinuses, salivary glands, and head and neck skin) who are candidates for radiation treatment
18 years of age or older
Must not have any contraindications for a MRI scan
Can not be pregnant
Must be fluent in English
Applicable Disease Sites
Head and Neck; Melanoma/Skin cancer
Status
Open
Participating Institutions
UW Hospital and Clinics