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Role of NGS-based ThyroSeq panel in Cancer Diagnosis in Thyroid Nodules
The purpose of this research study is to find out if certain molecular/genetic laboratory tests are helpful in forming the correct diagnosis of thyroid nodules when the tests are using cells obtained during the fine needle aspiration (FNA) procedure.
Your cells that are left over from your FNA will be sent for molecular testing
When the researcher is notified of your thyroid results, if the result falls into a category indeterminate (not benign and not malignant), the researcher will send the coded research sample to a molecular lab at the University of Pittsburgh for testing. If the FNA returns a result that is determined to be benign or malignant, the researcher will properly discard the research sample. Once your research sample is sent to the molecular lab, the cells from your thyroid nodule will be used to isolate DNA (deoxyribonucleic acid) and RNA(ribonucleic acid) and to perform several tests for genetic abnormalities associated with thyroid cancer.
- Subjects age 18 or greater who have been diagnosed with thyroid nodule(s) and undergo routine clinical fine needle aspiration (FNA) of the nodule regardless of gender or race
Applicable Disease Sites
UW Hospital and Clinics