Timothy J. Kamp, MD, PhD, FACC Print Friendly Page
Faculty, University of Wisconsin School of Medicine and Public HealthDr. Kamp's clinical activities include general cardiology with an emphasis on noninvasive cardiac electrophysiology and heart failure. He directs an active research program which bridges from the basic functional and electrical properties of heart cells to clinical applications arising from these basic studies, including the use of stem cells to repair damaged heart muscle. Dr. Kamp participates widely in peer review activities, including the editorial board for the journals Circulation Research and Stem Cells, as well as serving on peer review panels for American Heart Association and National Institutes of Health.
Specialties
UW Health Clinics
Hospital Affiliation(s)
University of Wisconsin Hospital and Clinics (primary)
Meriter Hospital, Veterans Hospital - Wm. S. Middleton Memorial (secondary)
UW School of Medicine and Public Health
| Department of Medicine |
Professional Certifications and Education
| Board Certification |
Cardiovascular Disease
|
| Fellowship |
Johns Hopkins Hospital, Baltimore, MD
|
| Residency |
Johns Hopkins Hospital, Baltimore, MD
|
| Internship |
Johns Hopkins Hospital, Baltimore, MD
|
| Medical School |
University of Chicago Medical School, Chicago, IL, 1989
|
| Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000. |
Programs & Conditions
| Research |
Dr. Kamp's research focuses in three general and related areas: (1) cardiac ion channel proteins and their role in the electrical activity of the heart, including arrhythmias, (2) basic cellular abnormalities responsible for heart failure, and (3) stem cells for the generation of new heart cells and for repair of damaged heart muscle. |
PubMed Articles
-
Raval KK Tao R White BE De Lange WJ Koonce CH Yu J Kishnani PS Thomson JA Mosher DF Ralphe JC Kamp TJ .
Pompe Disease Results in a Golgi-based Glycosylation Deficit in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes. J Biol Chem. 2015 Jan 30;290(5):3121-36
[PubMed ID: 25488666]
-
Wrighton PJ Klim JR Hernandez BA Koonce CH Kamp TJ Kiessling LL .
Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18126-31
[PubMed ID: 25422477]
-
Ye L Chang YH Xiong Q Zhang P Zhang L Somasundaram P Lepley M Swingen C Su L Wendel JS Guo J Jang A Rosenbush D Greder L Dutton JR Zhang J Kamp TJ Kaufman DS Ge Y Zhang J .
Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells. Cell Stem Cell. 2014 Dec 4;15(6):750-61
[PubMed ID: 25479750]
-
Bedada FB Chan SS Metzger SK Zhang L Zhang J Garry DJ Kamp TJ Kyba M Metzger JM .
Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes. Stem Cell Reports. 2014 Oct 14;3(4):594-605
[PubMed ID: 25358788]
-
Fox IJ Daley GQ Goldman SA Huard J Kamp TJ Trucco M .
Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease. Science. 2014 Aug 22;345(6199):1247391
[PubMed ID: 25146295]
-
Spencer CI Baba S Nakamura K Hua EA Sears MA Fu CC Zhang J Balijepalli S Tomoda K Hayashi Y Lizarraga P Wojciak J Scheinman MM Aalto-Setälä K Makielski JC January CT Healy KE Kamp TJ Yamanaka S Conklin BR .
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Stem Cell Reports. 2014 Aug 12;3(2):269-81
[PubMed ID: 25254341]
-
Raval KK Kamp TJ .
Cardiomyopathy, mitochondria and Barth syndrome: iPSCs reveal a connection. Nat Med. 2014 Jun;20(6):585-6
[PubMed ID: 24901565]
-
Salick MR Napiwocki BN Sha J Knight GT Chindhy SA Kamp TJ Ashton RS Crone WC .
Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes. Biomaterials. 2014 May;35(15):4454-64
[PubMed ID: 24582552]
-
Lalit PA Hei DJ Raval AN Kamp TJ .
Induced pluripotent stem cells for post-myocardial infarction repair: remarkable opportunities and challenges. Circ Res. 2014 Apr 11;114(8):1328-45
[PubMed ID: 24723658]
-
Lian X Zhang J Zhu K Kamp TJ Palecek SP .
Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition. Stem Cells. 2013 Mar;31(3):447-57
[PubMed ID: 23193013]
-
Lian X Zhang J Azarin SM Zhu K Hazeltine LB Bao X Hsiao C Kamp TJ Palecek SP .
Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions. Nat Protoc. 2013 Jan;8(1):162-75
[PubMed ID: 23257984]
-
Zhang J Klos M Wilson GF Herman AM Lian X Raval KK Barron MR Hou L Soerens AG Yu J Palecek SP Lyons GE Thomson JA Herron TJ Jalife J Kamp TJ .
Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res. 2012 Oct 12;111(9):1125-36
[PubMed ID: 22912385]
-
Lian X Hsiao C Wilson G Zhu K Hazeltine LB Azarin SM Raval KK Zhang J Kamp TJ Palecek SP .
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1848-57
[PubMed ID: 22645348]
-
Best JM Kamp TJ .
Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytes. J Mol Cell Cardiol. 2012 Feb;52(2):376-87
[PubMed ID: 21888911]
-
Squirrell JM Fong JJ Ariza CA Mael A Meyer K Shevde NK Roopra A Lyons GE Kamp TJ Eliceiri KW Ogle BM .
Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency. PLoS One. 2012;7(8):e43708
[PubMed ID: 22952742]
-
Joers V Seneczko K Goecks NC Kamp TJ Hacker TA Brunner KG Engle JW Barnhart TE Nickles RJ Holden JE Emborg ME .
Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys. PLoS One. 2012;7(4):e35371
[PubMed ID: 22539969]
-
Kouris NA Schaefer JA Hatta M Freeman BT Kamp TJ Kawaoka Y Ogle BM .
Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming. Stem Cells Int. 2012;2012:414038
[PubMed ID: 22701126]
-
Ma J Guo L Fiene SJ Anson BD Thomson JA Kamp TJ Kolaja KL Swanson BJ January CT .
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2006-17
[PubMed ID: 21890694]
-
Cai W Zhang Y Kamp TJ .
Imaging of Induced Pluripotent Stem Cells: From Cellular Reprogramming to Transplantation. Am J Nucl Med Mol Imaging. 2011 Aug 1;1(1):18-28
[PubMed ID: 21841970]
-
Buschke DG Squirrell JM Ansari H Smith MA Rueden CT Williams JC Lyons GE Kamp TJ Eliceiri KW Ogle BM .
Multiphoton flow cytometry to assess intrinsic and extrinsic fluorescence in cellular aggregates: applications to stem cells. Microsc Microanal. 2011 Aug;17(4):540-54
[PubMed ID: 20684798]
