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Timothy J. Kamp, MD, PhD, FACC
 

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Timothy J. Kamp, MD, PhD, FACC Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Kamp's clinical activities include general cardiology with an emphasis on noninvasive cardiac electrophysiology and heart failure. He directs an active research program which bridges from the basic functional and electrical properties of heart cells to clinical applications arising from these basic studies, including the use of stem cells to repair damaged heart muscle. Dr. Kamp participates widely in peer review activities, including the editorial board for the journals Circulation Research and Stem Cells, as well as serving on peer review panels for American Heart Association and National Institutes of Health.

Specialties

Cardiovascular Medicine

Clinics

Research Park Clinic
(608) 263-1530 | (800) 323-8942 | Map
University Hospital
(608) 263-1530 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Cardiovascular Disease
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Residency The Johns Hopkins Hospital, Baltimore, MD
Internship The Johns Hopkins Hospital, Baltimore, MD
Medical School University of Chicago Medical School, Chicago, IL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Kamp's research focuses in three general and related areas: (1) cardiac ion channel proteins and their role in the electrical activity of the heart, including arrhythmias, (2) basic cellular abnormalities responsible for heart failure, and (3) stem cells for the generation of new heart cells and for repair of damaged heart muscle.

PubMed Articles
Cai W Zhang J de Lange WJ Gregorich ZR Karp H Farrell ET Mitchell SD Tucholski T Lin Z Biermann M McIlwain SJ Ralphe JC Kamp TJ Ge Y An Unbiased Proteomics Method to Assess the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Circ Res . 2019 Nov 8;125(11):936-953
[PubMed ID: 31573406]
Feng L Kamp TJ Patient-independent iPS cells and modeling long QT syndrome. Heart Rhythm . 2019 Nov;16(11):1696-1697
[PubMed ID: 31150820]
Alexanian RA Mahapatra K Lang D Vaidyanathan R Markandeya YS Gill RK Zhai AJ Dhillon A Lea MR Abozeid S Schmuck EG Raval AN Eckhardt LL Glukhov AV Lalit PA Kamp TJ Induced cardiac progenitor cells repopulate decellularized mouse heart scaffolds and differentiate to generate cardiac tissue. Biochim Biophys Acta Mol Cell Res . 2019 Oct 18;:118559
[PubMed ID: 31634503]
Egorov YV Lang D Tyan L Turner D Lim E Piro ZD Hernandez JJ Lodin R Wang R Schmuck EG Raval AN Ralphe CJ Kamp TJ Rosenshtraukh LV Glukhov AV Caveolae-Mediated Activation of Mechanosensitive Chloride Channels in Pulmonary Veins Triggers Atrial Arrhythmogenesis. J Am Heart Assoc . 2019 Oct 15;8(20):e012748
[PubMed ID: 31597508]
Jiwlawat N Lynch EM Napiwocki BN Stempien A Ashton RS Kamp TJ Crone WC Suzuki M Micropatterned substrates with physiological stiffness promote cell maturation and Pompe disease phenotype in human induced pluripotent stem cell-derived skeletal myocytes. Biotechnol Bioeng . 2019 Sep;116(9):2377-2392
[PubMed ID: 31131875]
Choong OK Chen CY Zhang J Lin JH Lin PJ Ruan SC Kamp TJ Hsieh PCH Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction. Theranostics . 2019;9(22):6550-6567
[PubMed ID: 31588235]
Chen CY Choong OK Liu LW Cheng YC Li SC Yen CYT Wu MR Chiang MH Tsang TJ Wu YW Lin LC Chen YL Lin WC Hacker TA Kamp TJ Hsieh PCH MicroRNA let-7-TGFBR3 signalling regulates cardiomyocyte apoptosis after infarction. EBioMedicine . 2019 Aug;46:236-247
[PubMed ID: 31401194]
Biermann M Cai W Lang D Hermsen J Profio L Zhou Y Czirok A Isai DG Napiwocki BN Rodriguez AM Brown ME Woon MT Shao A Han T Park D Hacker TA Crone WC Burlingham WJ Glukhov AV Ge Y Kamp TJ Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation. Stem Cells . 2019 Jul;37(7):910-923
[PubMed ID: 31087611]
Zhang J Tao R Campbell KF Carvalho JL Ruiz EC Kim GC Schmuck EG Raval AN da Rocha AM Herron TJ Jalife J Thomson JA Kamp TJ Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors. Nat Commun . 2019 May 20;10(1):2238
[PubMed ID: 31110246]
Qian Z Sharma D Jia W Radke D Kamp T Zhao F Engineering stem cell cardiac patch with microvascular features representative of native myocardium. Theranostics . 2019;9(8):2143-2157
[PubMed ID: 31149034]
Tyan L Foell JD Vincent KP Woon MT Mesquitta WT Lang D Best JM Ackerman MJ McCulloch AD Glukhov AV Balijepalli RC Kamp TJ Long QT syndrome caveolin-3 mutations differentially modulate K<sub>v</sub> 4 and Ca<sub>v</sub> 1.2 channels to contribute to action potential prolongation. J Physiol . 2019 Mar;597(6):1531-1551
[PubMed ID: 30588629]
Lee JJ Cheng SJ Huang CY Chen CY Feng L Hwang DY Kamp TJ Chen HC Hsieh PCH Primary cardiac manifestation of autosomal dominant polycystic kidney disease revealed by patient induced pluripotent stem cell-derived cardiomyocytes. EBioMedicine . 2019 Feb;40:675-684
[PubMed ID: 30639418]
Tang TWH Chen HC Chen CY Yen CYT Lin CJ Prajnamitra RP Chen LL Ruan SC Lin JH Lin PJ Lu HH Kuo CW Chang CM Hall AD Vivas EI Shui JW Chen P Hacker TA Rey FE Kamp TJ Hsieh PCH Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair. Circulation . 2019 Jan 29;139(5):647-659
[PubMed ID: 30586712]
Berry JL Zhu W Tang YL Krishnamurthy P Ge Y Cooke JP Chen Y Garry DJ Yang HT Rajasekaran NS Koch WJ Li S Domae K Qin G Cheng K Kamp TJ Ye L Hu S Ogle BM Rogers JM Abel ED Davis ME Prabhu SD Liao R Pu WT Wang Y Ping P Bursac N Vunjak-Novakovic G Wu JC Bolli R Menasché P Zhang J Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circ Res . 2019 Jan 4;124(1):161-169
[PubMed ID: 30605412]
Metzger JM Moore CF Boettcher CA Brunner KG Fleddermann RA Matsoff HN Resnikoff HA Bondarenko V Kamp TJ Hacker TA Barnhart TE Lao PJ Christian BT Nickles RJ Gallagher CL Holden JE Emborg ME In vivo imaging of inflammation and oxidative stress in a nonhuman primate model of cardiac sympathetic neurodegeneration. NPJ Parkinsons Dis . 2018;4:22
[PubMed ID: 30038956]
Garg P Garg V Shrestha R Sanguinetti MC Kamp TJ Wu JC Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists. Circ Res . 2018 Jul 6;123(2):224-243
[PubMed ID: 29976690]
Wright PT Bhogal NK Diakonov I Pannell LMK Perera RK Bork NI Schobesberger S Lucarelli C Faggian G Alvarez-Laviada A Zaccolo M Kamp TJ Balijepalli RC Lyon AR Harding SE Nikolaev VO Gorelik J Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β<sub>2</sub>AR-cAMP Responsiveness in Murine Hearts. Cell Rep . 2018 Apr 10;23(2):459-469
[PubMed ID: 29642004]
Brown ME Zhou Y McIntosh BE Norman IG Lou HE Biermann M Sullivan JA Kamp TJ Thomson JA Anagnostopoulos PV Burlingham WJ A Humanized Mouse Model Generated Using Surplus Neonatal Tissue. Stem Cell Reports . 2018 Apr 10;10(4):1175-1183
[PubMed ID: 29576539]
Hsieh PCH Kamp TJ To Be Young at Heart. Cell Stem Cell . 2018 Apr 5;22(4):475-476
[PubMed ID: 29625063]
Woon MT Long PA Reilly L Evans JM Keefe AM Lea MR Beglinger CJ Balijepalli RC Lee Y Olson TM Kamp TJ Pediatric Dilated Cardiomyopathy-Associated <i>LRRC10</i> (Leucine-Rich Repeat-Containing 10) Variant Reveals LRRC10 as an Auxiliary Subunit of Cardiac L-Type Ca<sup>2+</sup> Channels. J Am Heart Assoc . 2018 Feb 3;7(3)
[PubMed ID: 29431102]