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Nizar N. Jarjour, MD
 

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Nizar N. Jarjour, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Nizar Jarjour, MD, is the President of the UW Medical Foundation. Dr. Jarjour's clinical activities include staffing the outpatient  pulmonary clinic and directing the pulmonary diagnostics laboratory.

Specialties

Pulmonary and Critical Care Medicine

Asthma

Bronchiectasis

Chronic Cough

Chronic Obstructive Pulmonary Disease

Dyspnea (shortness of breath)

Pulmonary Function Test

Pulmonary Stress Test

Clinics

University Hospital
(608) 263-7203 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Internal Medicine
Pulmonary Disease
Critical Care Medicine
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency Cook County Hospital, Chicago, IL
Internship Cook County Hospital, Chicago, IL
Medical School Damascus University, Damascus, Syria

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Jarjour's research program include mechanisms of allergic inflammation, role of eosinophil in airway disease, pathogenesis of viral induced asthma exacerbations, etiology and characteristics of severe asthma, mechanisms of action of anti-asthma medication, airway remodeling and clinical aspects of asthma.


PubMed Articles
Shim SS Schiebler ML Evans MD Jarjour N Sorkness RL Denlinger L Rodriguez A Wenzel S Hoffman EA Lin CL Gierada DS Castro M Fain SB NHLBI Severe Asthma Research Program. Lumen area change (Delta Lumen) between inspiratory and expiratory CT as a measure of severe outcomes in asthma. J Allergy Clin Immunol . 2018 Feb 10;
[PubMed ID: 29438772]
Dunican EM Elicker BM Gierada DS Nagle SK Schiebler ML Newell JD Raymond WW Lachowicz-Scroggins ME Di Maio S Hoffman EA Castro M Fain SB Jarjour NN Israel E Levy BD Erzurum SC Wenzel SE Meyers DA Bleecker ER Phillips BR Mauger DT Gordon ED Woodruff PG Peters MC Fahy JV National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP). Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest . 2018 Feb 5;
[PubMed ID: 29400693]
Zha W Kruger SJ Cadman RV Mummy DG Evans MD Nagle SK Denlinger LC Jarjour NN Sorkness RL Fain SB Regional Heterogeneity of Lobar Ventilation in Asthma Using Hyperpolarized Helium-3 MRI. Acad Radiol . 2018 Feb;25(2):169-178
[PubMed ID: 29174189]
Wong-McGrath K Denlinger LC Bleecker ER Castro M Gaston B Israel E Jarjour NN Mauger DT Peters S Phillips BR Wenzel SE Fahy JV Peters MC National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control. Chest . 2018 Feb;153(2):378-386
[PubMed ID: 29080709]
Evans MD Esnault S Denlinger LC Jarjour NN Sputum cell IL-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. J Allergy Clin Immunol . 2017 Dec 26;
[PubMed ID: 29103994]
Schwantes EA Evans MD Cuskey A Burford A Smith JA Lemanske RF Jr Jarjour NN Mathur SK Elevated fractional exhaled nitric oxide and blood eosinophil counts are associated with a 17q21 asthma risk allele in adult subjects. J Asthma Allergy . 2018;11:1-9
[PubMed ID: 29296089]
Kelly EA Esnault S Liu LY Evans MD Johansson MW Mathur S Mosher DF Denlinger LC Jarjour NN Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma. Am J Respir Crit Care Med . 2017 Dec 1;196(11):1385-1395
[PubMed ID: 28862877]
Mummy DG Kruger SJ Zha W Sorkness RL Jarjour NN Schiebler ML Denlinger LC Evans MD Fain SB Ventilation defect percent in helium-3 magnetic resonance imaging as a biomarker of severe outcomes in asthma. J Allergy Clin Immunol . 2017 Nov 10;
[PubMed ID: 29129582]
Esnault S Bernau K Torr EE Bochkov YA Jarjour NN Sandbo N RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism. Respir Res . 2017 Nov 10;18(1):188
[PubMed ID: 29126429]
Choi S Haghighi B Choi J Hoffman EA Comellas AP Newell JD Wenzel SE Castro M Fain SB Jarjour NN Schiebler ML Barr RG Han MK Bleecker ER Cooper CB Couper D Hansel N Kanner RE Kazeroni EA Kleerup EAC Martinez FJ O'Neal WK Woodruff PG Lin CL Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respir Res . 2017;4(1):e000252
[PubMed ID: 29435345]
Gomez JL Yan X Holm CT Grant N Liu Q Cohn L Nezgovorova V Meyers DA Bleecker ER Crisafi GM Jarjour NN Rogers L Reibman J Chupp GL SARP Investigators. Characterisation of asthma subgroups associated with circulating YKL-40 levels. Eur Respir J . 2017 Oct;50(4)
[PubMed ID: 29025889]
Choi S Hoffman EA Wenzel SE Castro M Fain S Jarjour N Schiebler ML Chen K Lin CL National Heart, Lung and Blood Institute's Severe Asthma Research Program. Quantitative computed tomographic imaging-based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes. J Allergy Clin Immunol . 2017 Sep;140(3):690-700.e8
[PubMed ID: 28143694]
Teague WG Phillips BR Fahy JV Wenzel SE Fitzpatrick AM Moore WC Hastie AT Bleecker ER Meyers DA Peters SP Castro M Coverstone AM Bacharier LB Ly NP Peters MC Denlinger LC Ramratnam S Sorkness RL Gaston BM Erzurum SC Comhair SAA Myers RE Zein J DeBoer MD Irani AM Israel E Levy B Cardet JC Phipatanakul W Gaffin JM Holguin F Fajt ML Aujla SJ Mauger DT Jarjour NN Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract . 2017 Aug 31;
[PubMed ID: 28866107]
Shen ZJ Hu J Kashi VP Kelly EA Denlinger LC Lutchman K McDonald JG Jarjour NN Malter JS Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways. Am J Respir Crit Care Med . 2017 Jun 15;195(12):1576-1585
[PubMed ID: 28125291]
Modena BD Bleecker ER Busse WW Erzurum SC Gaston BM Jarjour NN Meyers DA Milosevic J Tedrow JR Wu W Kaminski N Wenzel SE Gene Expression Correlated with Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease. Am J Respir Crit Care Med . 2017 Jun 1;195(11):1449-1463
[PubMed ID: 27984699]
Phipatanakul W Mauger DT Sorkness RL Gaffin JM Holguin F Woodruff PG Ly NP Bacharier LB Bhakta NR Moore WC Bleecker ER Hastie AT Meyers DA Castro M Fahy JV Fitzpatrick AM Gaston BM Jarjour NN Levy BD Peters SP Teague WG Fajt M Wenzel SE Erzurum SC Israel E Severe Asthma Research Program. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med . 2017 Jun 1;195(11):1439-1448
[PubMed ID: 27967215]
Cahill KN Katz HR Cui J Lai J Kazani S Crosby-Thompson A Garofalo D Castro M Jarjour N DiMango E Erzurum S Trevor JL Shenoy K Chinchilli VM Wechsler ME Laidlaw TM Boyce JA Israel E KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma. N Engl J Med . 2017 May 18;376(20):1911-1920
[PubMed ID: 28514613]
Duvall MG Barnig C Cernadas M Ricklefs I Krishnamoorthy N Grossman NL Bhakta NR Fahy JV Bleecker ER Castro M Erzurum SC Gaston BM Jarjour NN Mauger DT Wenzel SE Comhair SA Coverstone AM Fajt ML Hastie AT Johansson MW Peters MC Phillips BR Israel E Levy BD National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol . 2017 Mar 10;2(9)
[PubMed ID: 28783702]
Denlinger LC Phillips BR Ramratnam S Ross K Bhakta NR Cardet JC Castro M Peters SP Phipatanakul W Aujla S Bacharier LB Bleecker ER Comhair SA Coverstone A DeBoer M Erzurum SC Fain SB Fajt M Fitzpatrick AM Gaffin J Gaston B Hastie AT Hawkins GA Holguin F Irani AM Israel E Levy BD Ly N Meyers DA Moore WC Myers R Opina MT Peters MC Schiebler ML Sorkness RL Teague WG Wenzel SE Woodruff PG Mauger DT Fahy JV Jarjour NN National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med . 2017 Feb 1;195(3):302-313
[PubMed ID: 27556234]
Esnault S Torr EE Bernau K Johansson MW Kelly EA Sandbo N Jarjour NN Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation. PLoS One . 2017;12(1):e0170207
[PubMed ID: 28095470]