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Nizar N. Jarjour, MD
 

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Nizar N. Jarjour, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Nizar Jarjour, MD, Senior Vice President, Chief Academic Integration Officer for UW Health and President of the UW Medical Foundation. Dr. Jarjour's clinical activities include staffing the outpatient  pulmonary clinic and directing the pulmonary diagnostics laboratory.

Specialties

Pulmonary and Critical Care Medicine

Asthma

Bronchiectasis

Chronic Cough

Chronic Obstructive Pulmonary Disease

Dyspnea (shortness of breath)

Pulmonary Function Test

Pulmonary Stress Test

Clinics

University Hospital
(608) 263-7203 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Critical Care Medicine
Internal Medicine
Pulmonary Disease
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency Cook County Hospital, Chicago, IL
Internship Cook County Hospital, Chicago, IL
Medical School Damascus University, Damascus, Syria

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Jarjour's research program include mechanisms of allergic inflammation, role of eosinophil in airway disease, pathogenesis of viral induced asthma exacerbations, etiology and characteristics of severe asthma, mechanisms of action of anti-asthma medication, airway remodeling and clinical aspects of asthma.


PubMed Articles
Hastie AT Mauger DT Denlinger LC Coverstone A Castro M Erzurum S Jarjour N Levy BD Meyers DA Moore WC Phillips BR Wenzel SE Fahy JV Israel E Bleecker ER Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. Am J Respir Crit Care Med . 2021 Apr 1;203(7):882-892
[PubMed ID: 33545021]
Denlinger LC Phillips BR Sorkness RL Bleecker ER Castro M DeBoer MD Fitzpatrick AM Hastie AT Gaffin JM Moore WC Peters MC Peters SP Phipatanakul W Cardet JC Erzurum SC Fahy JV Fajt ML Gaston B Levy BD Meyers DA Ross K Teague WG Wenzel SE Woodruff PG Zein J Jarjour NN Mauger DT Israel E Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma. Am J Respir Crit Care Med . 2021 Apr 1;203(7):841-852
[PubMed ID: 33290668]
Esnault S Khosravi M Kelly EA Liu LY Bochkov YA Tattersall MC Jarjour NN Increased IL-6 and Potential IL-6 trans-signalling in the airways after an allergen challenge. Clin Exp Allergy . 2021 Apr;51(4):564-573
[PubMed ID: 33471392]
Zein JG McManus JM Sharifi N Erzurum SC Marozkina N Lahm T Giddings O Davis MD DeBoer MD Comhair SA Bazeley P Kim HJ Busse W Calhoun W Castro M Chung KF Fahy JV Israel E Jarjour NN Levy BD Mauger DT Moore WC Ortega VE Peters M Bleecker ER Meyers DA Zhao Y Wenzel SE Gaston B NHLBI Severe Asthma Research Program (SARP). Benefits of Airway Androgen Receptor Expression in Human Asthma. Am J Respir Crit Care Med . 2021 Mar 29;
[PubMed ID: 33779531]
Bernau K Leet JP Floerke H Bruhn EM Noll AL McDermott IS Esnault S Jarjour NN Sandbo N Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation. Cells . 2021 Mar 2;10(3)
[PubMed ID: 33801398]
Israel E Denlinger LC Bacharier LB LaVange LM Moore WC Peters MC Georas SN Wright RJ Mauger DT Noel P Akuthota P Bach J Bleecker ER Cardet JC Carr TF Castro M Cinelli A Comhair SAA Covar RA Alexander LC DiMango EA Erzurum SC Fahy JV Fajt ML Gaston BM Hoffman EA Holguin F Jackson DJ Jain S Jarjour NN Ji Y Kenyon NJ Kosorok MR Kraft M Krishnan JA Kumar R Liu AH Liu MC Ly NP Marquis MA Martinez FD Moy JN O'Neal WK Ortega VE Peden DB Phipatanakul W Ross K Smith LJ Szefler SJ Teague WG Tulchinsky AF Vijayanand P Wechsler ME Wenzel SE White SR Zeki AA Ivanova A PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment. J Allergy Clin Immunol . 2021 Mar 2;
[PubMed ID: 33667479]
Li X Christenson SA Modena B Li H Busse WW Castro M Denlinger LC Erzurum SC Fahy JV Gaston B Hastie AT Israel E Jarjour NN Levy BD Moore WC Woodruff PG Kaminski N Wenzel SE Bleecker ER Meyers DA NHLBI Severe Asthma Research Program (SARP). Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways. J Allergy Clin Immunol . 2021 Mar;147(3):894-909
[PubMed ID: 32795586]
Barretto KT Mosher DF Jarjour NN Curran CS Esnault S Johansson MW Observation and Quantification of Eosinophil Motility. Methods Mol Biol . 2021;2241:139-148
[PubMed ID: 33486734]
Peters MC Mauger D Ross KR Phillips B Gaston B Cardet JC Israel E Levy BD Phipatanakul W Jarjour NN Castro M Wenzel SE Hastie A Moore W Bleecker E Fahy JV Denlinger LC Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency. Am J Respir Crit Care Med . 2020 Oct 1;202(7):973-982
[PubMed ID: 32479111]
Mummy DG Carey KJ Evans MD Denlinger LC Schiebler ML Sorkness RL Jarjour NN Fain SB Ventilation defects on hyperpolarized helium-3 MRI in asthma are predictive of 2-year exacerbation frequency. J Allergy Clin Immunol . 2020 Oct;146(4):831-839.e6
[PubMed ID: 32173351]
Barretto KT Brockman-Schneider RA Kuipers I Basnet S Bochkov YA Altman MC Jarjour NN Gern JE Esnault S Human airway epithelial cells express a functional IL-5 receptor. Allergy . 2020 Aug;75(8):2127-2130
[PubMed ID: 32246831]
Peters MC Sajuthi S Deford P Christenson S Rios CL Montgomery MT Woodruff PG Mauger DT Erzurum SC Johansson MW Denlinger LC Jarjour NN Castro M Hastie AT Moore W Ortega VE Bleecker ER Wenzel SE Israel E Levy BD Seibold MA Fahy JV COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids. Am J Respir Crit Care Med . 2020 Jul 1;202(1):83-90
[PubMed ID: 32348692]
Tsuchiya N Schiebler ML Evans MD Cadman RV Sorkness RL Lemanske RF Jr Jackson DJ Jarjour NN Denlinger LC Fain SB Safety of repeated hyperpolarized helium 3 magnetic resonance imaging in pediatric asthma patients. Pediatr Radiol . 2020 May;50(5):646-655
[PubMed ID: 31980848]
Wiesner DL Merkhofer RM Ober C Kujoth GC Niu M Keller NP Gern JE Brockman-Schneider RA Evans MD Jackson DJ Warner T Jarjour NN Esnault SJ Feldman MB Freeman M Mou H Vyas JM Klein BS Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe . 2020 Apr 8;27(4):614-628.e6
[PubMed ID: 32130954]
Ash SY Sanchez-Ferrero GV Schiebler ML Rahaghi FN Rai A Come CE Ross JC Colon AG Cardet JC Bleecker ER Castro M Fahy JV Fain SB Gaston BM Hoffman EA Jarjour NN Lempel JK Mauger DT Tattersall MC Wenzel SE Levy BD Washko GR Israel E San Jose Estepar R SARP Investigators. Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort. Chest . 2020 Feb;157(2):258-267
[PubMed ID: 31521672]
Esnault S Leet JP Johansson MW Barretto KT Fichtinger PS Fogerty FJ Bernau K Mathur SK Mosher DF Sandbo N Jarjour NN Eosinophil cytolysis on Immunoglobulin G is associated with microtubule formation and suppression of rho-associated protein kinase signalling. Clin Exp Allergy . 2020 Feb;50(2):198-212
[PubMed ID: 31750580]
Zein J Gaston B Bazeley P DeBoer MD Igo RP Jr Bleecker ER Meyers D Comhair S Marozkina NV Cotton C Patel M Alyamani M Xu W Busse WW Calhoun WJ Ortega V Hawkins GA Castro M Chung KF Fahy JV Fitzpatrick AM Israel E Jarjour NN Levy B Mauger DT Moore WC Noel P Peters SP Teague WG Wenzel SE Erzurum SC Sharifi N <i>HSD3B1</i> genotype identifies glucocorticoid responsiveness in severe asthma. Proc Natl Acad Sci U S A . 2020 Jan 28;117(4):2187-2193
[PubMed ID: 31932420]
Holguin F Cardet JC Chung KF Diver S Ferreira DS Fitzpatrick A Gaga M Kellermeyer L Khurana S Knight S McDonald VM Morgan RL Ortega VE Rigau D Subbarao P Tonia T Adcock IM Bleecker ER Brightling C Boulet LP Cabana M Castro M Chanez P Custovic A Djukanovic R Frey U Frankemölle B Gibson P Hamerlijnck D Jarjour N Konno S Shen H Vitary C Bush A Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J . 2020 Jan;55(1)
[PubMed ID: 31558662]
Johansson MW Grill BM Barretto KT Favour MC Schira HM Swanson CM Lee KE Sorkness RL Mosher DF Denlinger LC Jarjour NN Plasma P-Selectin Is Inversely Associated with Lung Function and Corticosteroid Responsiveness in Asthma. Int Arch Allergy Immunol . 2020;181(11):879-887
[PubMed ID: 32777786]
Ross KR Gupta R DeBoer MD Zein J Phillips BR Mauger DT Li C Myers RE Phipatanakul W Fitzpatrick AM Ly NP Bacharier LB Jackson DJ Celedón JC Larkin A Israel E Levy B Fahy JV Castro M Bleecker ER Meyers D Moore WC Wenzel SE Jarjour NN Erzurum SC Teague WG Gaston B Severe asthma during childhood and adolescence: A longitudinal study. J Allergy Clin Immunol . 2020 Jan;145(1):140-146.e9
[PubMed ID: 31622688]