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Nizar N. Jarjour, MD
 

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Nizar N. Jarjour, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Nizar Jarjour, MD, Senior Vice President, Chief Academic Integration Officer for UW Health and President of the UW Medical Foundation. Dr. Jarjour's clinical activities include staffing the outpatient  pulmonary clinic and directing the pulmonary diagnostics laboratory.

Specialties

Pulmonary and Critical Care Medicine

Asthma

Bronchiectasis

Chronic Cough

Chronic Obstructive Pulmonary Disease

Dyspnea (shortness of breath)

Pulmonary Function Test

Pulmonary Stress Test

Clinics

University Hospital
(608) 263-7203 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Critical Care Medicine
Internal Medicine
Pulmonary Disease
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency Cook County Hospital, Chicago, IL
Internship Cook County Hospital, Chicago, IL
Medical School Damascus University, Damascus, Syria

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Jarjour's research program include mechanisms of allergic inflammation, role of eosinophil in airway disease, pathogenesis of viral induced asthma exacerbations, etiology and characteristics of severe asthma, mechanisms of action of anti-asthma medication, airway remodeling and clinical aspects of asthma.


PubMed Articles
Weathington N O'Brien ME Radder JE Whisenant TC Bleecker ER Busse WW Erzurum SC Gaston B Jarjour NN Meyers DA Milosevic J Tedrow JR Trudeau JB Wong HP Wu W Kaminski N Wenzel SE Modena BD Bronchoalveolar Lavage Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications. Am J Respir Crit Care Med . 2019 Jun 4;
[PubMed ID: 31161938]
Wu W Bang S Bleecker ER Castro M Denlinger L Erzurum SC Fahy JV Fitzpatrick AM Gaston BM Hastie AT Israel E Jarjour NN Levy BD Mauger DT Meyers DA Moore WC Peters M Phillips BR Phipatanakul W Sorkness RL Wenzel SE Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med . 2019 Jun 1;199(11):1358-1367
[PubMed ID: 30682261]
Fitzpatrick AM Gillespie SE Mauger DT Phillips BR Bleecker ER Israel E Meyers DA Moore WC Sorkness RL Wenzel SE Bacharier LB Castro M Denlinger LC Erzurum SC Fahy JV Gaston BM Jarjour NN Larkin A Levy BD Ly NP Ortega VE Peters SP Phipatanakul W Ramratnam S Teague WG Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol . 2019 Jun;143(6):2052-2061
[PubMed ID: 30635198]
Lachowicz-Scroggins ME Dunican EM Charbit AR Raymond W Looney MR Peters MC Gordon ED Woodruff PG Lefrançais E Phillips BR Mauger DT Comhair SA Erzurum SC Johansson MW Jarjour NN Coverstone AM Castro M Hastie AT Bleecker ER Fajt ML Wenzel SE Israel E Levy BD Fahy JV Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med . 2019 May 1;199(9):1076-1085
[PubMed ID: 30888839]
Sorkness RL Kienert C O'Brien MJ Fain SB Jarjour NN Compressive air trapping in asthma: effects of age, sex, and severity. J Appl Physiol (1985) . 2019 May 1;126(5):1265-1271
[PubMed ID: 30844338]
Schaefer N Li X Seibold MA Jarjour NN Denlinger LC Castro M Coverstone AM Teague WG Boomer J Bleecker ER Meyers DA Moore WC Hawkins GA Fahy J Phillips BR Mauger DT Dakhama A Gellatly S Pavelka N Berman R Di YP Wenzel SE Chu HW The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium. JCI Insight . 2019 Apr 18;4(8)
[PubMed ID: 30996135]
Siddiqui S Denlinger LC Fowler SJ Akuthota P Shaw DE Heaney LG Brown L Castro M Winders TA Kraft M Wagers S Peters MC Pavord ID Walker S Jarjour NN Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials. Bridging Clinical and Patient Perspectives. Am J Respir Crit Care Med . 2019 Apr 1;199(7):823-829
[PubMed ID: 30726120]
Choi J LeBlanc LJ Choi S Haghighi B Hoffman EA O'Shaughnessy P Wenzel SE Castro M Fain S Jarjour N Schiebler ML Denlinger L Delvadia R Walenga R Babiskin A Lin CL Differences in Particle Deposition Between Members of Imaging-Based Asthma Clusters. J Aerosol Med Pulm Drug Deliv . 2019 Mar 19;
[PubMed ID: 30888242]
Zhou X Kinlough CL Hughey RP Jin M Inoue H Etling E Modena BD Kaminski N Bleecker ER Meyers DA Jarjour NN Trudeau JB Holguin F Ray A Wenzel SE Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight . 2019 Mar 7;4(5)
[PubMed ID: 30730306]
Khurana S Jarjour NN Systematic Approach to Asthma of Varying Severity. Clin Chest Med . 2019 Mar;40(1):59-70
[PubMed ID: 30691717]
Esnault S Kelly EA Johnson SH DeLain LP Haedt MJ Noll AL Sandbo N Jarjour NN Matrix Metalloproteinase-9-Dependent Release of IL-1<i>β</i> by Human Eosinophils. Mediators Inflamm . 2019;2019:7479107
[PubMed ID: 30906226]
Peters MC Kerr S Dunican EM Woodruff PG Fajt ML Levy BD Israel E Phillips BR Mauger DT Comhair SA Erzurum SC Johansson MW Jarjour NN Coverstone AM Castro M Hastie AT Bleecker ER Wenzel SE Fahy JV National Heart, Lung and Blood Institute Severe Asthma Research Program 3. Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol . 2019 Jan;143(1):104-113.e14
[PubMed ID: 29524537]
Shim SS Schiebler ML Evans MD Jarjour N Sorkness RL Denlinger LC Rodriguez A Wenzel S Hoffman EA Lin CL Gierada DS Castro M Fain SB National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Lumen area change (Delta Lumen) between inspiratory and expiratory multidetector computed tomography as a measure of severe outcomes in asthmatic patients. J Allergy Clin Immunol . 2018 Dec;142(6):1773-1780.e9
[PubMed ID: 29438772]
Bernau K Leet JP Esnault S Noll AL Evans MD Jarjour NN Sandbo N Eosinophil-degranulation products drive a proinflammatory fibroblast phenotype. J Allergy Clin Immunol . 2018 Oct;142(4):1360-1363.e3
[PubMed ID: 29936102]
Moon HG Kim SJ Jeong JJ Han SS Jarjour NN Lee H Abboud-Werner SL Chung S Choi HS Natarajan V Ackerman SJ Christman JW Park GY Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization. Immunity . 2018 Aug 21;49(2):275-287.e5
[PubMed ID: 30054206]
Krishnamoorthy N Douda DN Brüggemann TR Ricklefs I Duvall MG Abdulnour RE Martinod K Tavares L Wang X Cernadas M Israel E Mauger DT Bleecker ER Castro M Erzurum SC Gaston BM Jarjour NN Wenzel S Dunican E Fahy JV Irimia D Wagner DD Levy BD National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators. Neutrophil cytoplasts induce T<sub>H</sub>17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol . 2018 Aug 3;3(26)
[PubMed ID: 30076281]
Evans MD Esnault S Denlinger LC Jarjour NN Sputum cell IL-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. J Allergy Clin Immunol . 2018 Aug;142(2):415-423
[PubMed ID: 29103994]
Ash SY Rahaghi FN Come CE Ross JC Colon AG Cardet-Guisasola JC Dunican EM Bleecker ER Castro M Fahy JV Fain SB Gaston BM Hoffman EA Jarjour NN Mauger DT Wenzel SE Levy BD San Jose Estepar R Israel E Washko GR SARP Investigators. Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med . 2018 Jul 1;198(1):39-50
[PubMed ID: 29672122]
Esnault S Hebert AS Jarjour NN Coon JJ Mosher DF Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3. J Proteome Res . 2018 Jun 1;17(6):2102-2111
[PubMed ID: 29706072]
DeBoer MD Phillips BR Mauger DT Zein J Erzurum SC Fitzpatrick AM Gaston BM Myers R Ross KR Chmiel J Lee MJ Fahy JV Peters M Ly NP Wenzel SE Fajt ML Holguin F Moore WC Peters SP Meyers D Bleecker ER Castro M Coverstone AM Bacharier LB Jarjour NN Sorkness RL Ramratnam S Irani AM Israel E Levy B Phipatanakul W Gaffin JM Gerald Teague W Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med . 2018 Apr 10;18(1):58
[PubMed ID: 29631584]