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Nizar N. Jarjour, MD
 

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Nizar N. Jarjour, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Nizar Jarjour, MD, Senior Vice President, Chief Academic Integration Officer for UW Health and President of the UW Medical Foundation. Dr. Jarjour's clinical activities include staffing the outpatient  pulmonary clinic and directing the pulmonary diagnostics laboratory.

Specialties

Pulmonary and Critical Care Medicine

Asthma

Bronchiectasis

Chronic Cough

Chronic Obstructive Pulmonary Disease

Dyspnea (shortness of breath)

Pulmonary Function Test

Pulmonary Stress Test

Clinics

University Hospital
(608) 263-7203 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Critical Care Medicine
Internal Medicine
Pulmonary Disease
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency Cook County Hospital, Chicago, IL
Internship Cook County Hospital, Chicago, IL
Medical School Damascus University, Damascus, Syria

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Jarjour's research program include mechanisms of allergic inflammation, role of eosinophil in airway disease, pathogenesis of viral induced asthma exacerbations, etiology and characteristics of severe asthma, mechanisms of action of anti-asthma medication, airway remodeling and clinical aspects of asthma.


PubMed Articles
Moon HG Kim SJ Jeong JJ Han SS Jarjour NN Lee H Abboud-Werner SL Chung S Choi HS Natarajan V Ackerman SJ Christman JW Park GY Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization. Immunity . 2018 Aug 21;49(2):275-287.e5
[PubMed ID: 30054206]
Krishnamoorthy N Douda DN Brüggemann TR Ricklefs I Duvall MG Abdulnour RE Martinod K Tavares L Wang X Cernadas M Israel E Mauger DT Bleecker ER Castro M Erzurum SC Gaston BM Jarjour NN Wenzel S Dunican E Fahy JV Irimia D Wagner DD Levy BD National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators. Neutrophil cytoplasts induce T<sub>H</sub>17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol . 2018 Aug 3;3(26)
[PubMed ID: 30076281]
Evans MD Esnault S Denlinger LC Jarjour NN Sputum cell IL-1 receptor expression level is a marker of airway neutrophilia and airflow obstruction in asthmatic patients. J Allergy Clin Immunol . 2018 Aug;142(2):415-423
[PubMed ID: 29103994]
Ash SY Rahaghi FN Come CE Ross JC Colon AG Cardet-Guisasola JC Dunican EM Bleecker ER Castro M Fahy JV Fain SB Gaston BM Hoffman EA Jarjour NN Mauger DT Wenzel SE Levy BD San Jose Estepar R Israel E Washko GR SARP Investigators. Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort. Am J Respir Crit Care Med . 2018 Jul 1;198(1):39-50
[PubMed ID: 29672122]
Bernau K Leet JP Esnault S Noll AL Evans MD Jarjour NN Sandbo N Eosinophil-degranulation products drive a proinflammatory fibroblast phenotype. J Allergy Clin Immunol . 2018 Jun 21;
[PubMed ID: 29936102]
Esnault S Hebert AS Jarjour NN Coon JJ Mosher DF Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3. J Proteome Res . 2018 Jun 1;17(6):2102-2111
[PubMed ID: 29706072]
DeBoer MD Phillips BR Mauger DT Zein J Erzurum SC Fitzpatrick AM Gaston BM Myers R Ross KR Chmiel J Lee MJ Fahy JV Peters M Ly NP Wenzel SE Fajt ML Holguin F Moore WC Peters SP Meyers D Bleecker ER Castro M Coverstone AM Bacharier LB Jarjour NN Sorkness RL Ramratnam S Irani AM Israel E Levy B Phipatanakul W Gaffin JM Gerald Teague W Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med . 2018 Apr 10;18(1):58
[PubMed ID: 29631584]
Peters MC Kerr S Dunican EM Woodruff PG Fajt ML Levy BD Israel E Phillips BR Mauger DT Comhair SA Erzurum SC Johansson MW Jarjour NN Coverstone AM Castro M Hastie AT Bleecker ER Wenzel SE Fahy JV National Heart, Lung and Blood Institute Severe Asthma Research Program 3. Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol . 2018 Mar 7;
[PubMed ID: 29524537]
Mummy DG Kruger SJ Zha W Sorkness RL Jarjour NN Schiebler ML Denlinger LC Evans MD Fain SB Ventilation defect percent in helium-3 magnetic resonance imaging as a biomarker of severe outcomes in asthma. J Allergy Clin Immunol . 2018 Mar;141(3):1140-1141.e4
[PubMed ID: 29129582]
Dunican EM Elicker BM Gierada DS Nagle SK Schiebler ML Newell JD Raymond WW Lachowicz-Scroggins ME Di Maio S Hoffman EA Castro M Fain SB Jarjour NN Israel E Levy BD Erzurum SC Wenzel SE Meyers DA Bleecker ER Phillips BR Mauger DT Gordon ED Woodruff PG Peters MC Fahy JV National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP). Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest . 2018 Mar 1;128(3):997-1009
[PubMed ID: 29400693]
Shim SS Schiebler ML Evans MD Jarjour N Sorkness RL Denlinger LC Rodriguez A Wenzel S Hoffman EA Lin CL Gierada DS Castro M Fain SB National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Lumen area change (Delta Lumen) between inspiratory and expiratory multidetector computed tomography as a measure of severe outcomes in asthmatic patients. J Allergy Clin Immunol . 2018 Feb 10;
[PubMed ID: 29438772]
Zha W Kruger SJ Cadman RV Mummy DG Evans MD Nagle SK Denlinger LC Jarjour NN Sorkness RL Fain SB Regional Heterogeneity of Lobar Ventilation in Asthma Using Hyperpolarized Helium-3 MRI. Acad Radiol . 2018 Feb;25(2):169-178
[PubMed ID: 29174189]
Wong-McGrath K Denlinger LC Bleecker ER Castro M Gaston B Israel E Jarjour NN Mauger DT Peters S Phillips BR Wenzel SE Fahy JV Peters MC National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control. Chest . 2018 Feb;153(2):378-386
[PubMed ID: 29080709]
Johansson MW Kelly EA Nguyen CL Jarjour NN Bochner BS Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge. Int Arch Allergy Immunol . 2018;177(1):16-28
[PubMed ID: 29879704]
Teague WG Phillips BR Fahy JV Wenzel SE Fitzpatrick AM Moore WC Hastie AT Bleecker ER Meyers DA Peters SP Castro M Coverstone AM Bacharier LB Ly NP Peters MC Denlinger LC Ramratnam S Sorkness RL Gaston BM Erzurum SC Comhair SAA Myers RE Zein J DeBoer MD Irani AM Israel E Levy B Cardet JC Phipatanakul W Gaffin JM Holguin F Fajt ML Aujla SJ Mauger DT Jarjour NN Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract . 2018 Mar - Apr;6(2):545-554.e4
[PubMed ID: 28866107]
Schwantes EA Evans MD Cuskey A Burford A Smith JA Lemanske RF Jr Jarjour NN Mathur SK Elevated fractional exhaled nitric oxide and blood eosinophil counts are associated with a 17q21 asthma risk allele in adult subjects. J Asthma Allergy . 2018;11:1-9
[PubMed ID: 29296089]
Kelly EA Esnault S Liu LY Evans MD Johansson MW Mathur S Mosher DF Denlinger LC Jarjour NN Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma. Am J Respir Crit Care Med . 2017 Dec 1;196(11):1385-1395
[PubMed ID: 28862877]
Esnault S Bernau K Torr EE Bochkov YA Jarjour NN Sandbo N RNA-sequencing analysis of lung primary fibroblast response to eosinophil-degranulation products predicts downstream effects on inflammation, tissue remodeling and lipid metabolism. Respir Res . 2017 Nov 10;18(1):188
[PubMed ID: 29126429]
Choi S Haghighi B Choi J Hoffman EA Comellas AP Newell JD Wenzel SE Castro M Fain SB Jarjour NN Schiebler ML Barr RG Han MK Bleecker ER Cooper CB Couper D Hansel N Kanner RE Kazerooni EA Kleerup EAC Martinez FJ O'Neal WK Woodruff PG Lin CL Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respir Res . 2017;4(1):e000252
[PubMed ID: 29435345]
Gomez JL Yan X Holm CT Grant N Liu Q Cohn L Nezgovorova V Meyers DA Bleecker ER Crisafi GM Jarjour NN Rogers L Reibman J Chupp GL SARP Investigators. Characterisation of asthma subgroups associated with circulating YKL-40 levels. Eur Respir J . 2017 Oct;50(4)
[PubMed ID: 29025889]