Margo Lyn Hoover-Regan, MD close

Margo Lyn Hoover-Regan, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Margo Hoover-Regan is the Clinical Director of our Pediatric Hematology/Oncology program and an associate professor in the Division of Pediatric Hematology, Oncology and Bone Marrow Transplant at the University of Wisconsin School of Medicine and Public Health. She earned her medical degree from University of Illinois College of Medicine, Peoria, IL, completed her residency at University of Chicago Hospitals, Chicago, IL and a fellowship at Children’s Memorial Hospital, Chicago, IL. Dr. Hoover-Regan is board certified in pediatrics and pediatric hematology/oncology. She cares for children with a variety of malignancies and evaluates and treats children with hematologic disorders. Her clinical focus involves pediatric palliative care and treating children with malignant bone tumors.


Pediatric Hematology and Oncology

Pediatric Palliative Care Medicine

Acute Lymphoblastic Leukemia

Adrenocortical carcinoma

Aplastic Anemia



Atypical Teratoid/Rhabdoid tumor

Bone Marrow Biopsy

Brain Stem Glioma


Chronic Myeloid Leukemia

Congenital Hemolytic Anemias


Cyclic Neutropenia

Diamond-Blackfan Syndrome

Endocrine Tumors


Ewing Sarcoma

Fanconi's Anemia

Germ Cell Tumors

Hemophagocytic Lymphohistiocytosis

Hemophilia A

Hemophilia B


Hereditary Spherocytosis

Hodgkin's Disease

I-131 MIBG (Metaiodobenzylguadine)

Immune Thrombocytopenc Purpura


Juvenile Myelomonocytic Leukemia

Kostmann Syndrome

Langerhans' Cell Histiocytosis

Lumbar Puncture


Myelodysplastic Syndromes

Neurocutaneous Syndrome


Non-Hodgkin Lymphomas

Optic Glioma


Paroxysmal Nocturnal Hemoglobinuria

Pediatric Cancer

Pediatric Sickle Cell Disease



Shwachman-Diamond Syndrome

Sturge-Weber Syndrome

Thalassemia Syndromes


Thyroid Tumors

Tuberous Sclerosis

Vascular malformations

Von Willebrand Disease

VonHippel-Lindau Disease


American Family Children's Hospital
(608) 890-9493 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map
SwedishAmerican Creekside Medical Center
(779) 696-8499 | | Map
University Hospital
(608) 890-9493 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics

Professional Certifications and Education

Board Certification Pediatrics
Pediatric Hematology-Oncology
Fellowship Children's Memorial Hospital, Chicago, IL
Residency University of Chicago Hospitals, Chicago, IL
Internship University of Chicago Hospitals, Chicago, IL
Medical School University of Illinois College of Medicine, Peoria, IL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Hoover-Regan cares for children with sarcomas and neuromuscular disorders, and leads our Pediatric Palliative Care program. She is also interested in benign hematology and has an outreach clinic in Pediatric Hematology/Oncology in Rockford, Ill.

PubMed Articles
Yu Q Zhong X Chen B Feng Y Ma M Diamond CA Voeller JS Kim M DeSantes KB Capitini CM Patel NJ Hoover-Regan ML Burke MJ Janko K Puccetti DM Ikonomidou C Li L Isobaric Labeling Strategy Utilizing 4-Plex <i>N</i>,<i>N</i>-Dimethyl Leucine (DiLeu) Tags Reveals Proteomic Changes Induced by Chemotherapy in Cerebrospinal Fluid of Children with B-Cell Acute Lymphoblastic Leukemia. J Proteome Res . 2020 Jul 2;19(7):2606-2616
[PubMed ID: 32396724]
Denu RA Matson DR Davis MJ Tedford NJ Brichta CE Diamond CA Hoover-Regan ML Association of Immune Thrombocytopenia and T-Lymphoblastic Lymphoma in a Pediatric Patient. Case Rep Hematol . 2019;2019:1425151
[PubMed ID: 31929920]
Graul-Conroy A Hoover-Regan M DeSantes KB Sondel PM Callander NS Longo WL Fahl WE Reduction in oral mucositis severity using a topical vasoconstrictor: A case report of three bone marrow transplant patients. Integr Cancer Sci Ther . 2018 Dec;5(6)
[PubMed ID: 31832233]
Wolfe AD Denniston SF Baker J Catrine K Hoover-Regan M Bad News Deserves Better Communication: A Customizable Curriculum for Teaching Learners to Share Life-Altering Information in Pediatrics. MedEdPORTAL . 2016 Aug 12;12:10438
[PubMed ID: 31139729]
Dingfield L Bender L Harris P Newport K Hoover-Regan M Feudtner C Clifford S Casarett D Comparison of pediatric and adult hospice patients using electronic medical record data from nine hospices in the United States, 2008-2012. J Palliat Med . 2015 Feb;18(2):120-6
[PubMed ID: 25411904]
Wolfe AD Frierdich SA Wish J Kilgore-Carlin J Plotkin JA Hoover-Regan M Sharing life-altering information: development of pediatric hospital guidelines and team training. J Palliat Med . 2014 Sep;17(9):1011-8
[PubMed ID: 24971650]
Hoover-Regan M Becker T Williams MJ Shenker Y Informed consent and research subject understanding of clinical trials. WMJ . 2013 Feb;112(1):18-23
[PubMed ID: 23513309]
Cairo MS Sposto R Perkins SL Meadows AT Hoover-Regan ML Anderson JR Siegel SE Lones MA Tedeschi-Blok N Kadin ME Kjeldsberg CR Wilson JF Sanger W Morris E Krailo MD Finlay JL Burkitt's and Burkitt-like lymphoma in children and adolescents: a review of the Children's Cancer Group experience. Br J Haematol . 2003 Feb;120(4):660-70
[PubMed ID: 12588354]
Cairo MS Sposto R Hoover-Regan M Meadows AT Anderson JR Siegel SE Kadin ME Kjeldsberg CR Wilson JF Perkins SL Lones MA Morris E Finlay JL Childhood and adolescent large-cell lymphoma (LCL): a review of the Children's Cancer Group experience. Am J Hematol . 2003 Jan;72(1):53-63
[PubMed ID: 12508269]
Hoover M Bowman LC Crawford SE Stack C Donaldson JS Grayhack JJ Tomita T Cohn SL Long-term outcome of patients with intraspinal neuroblastoma. Med Pediatr Oncol . 1999 May;32(5):353-9
[PubMed ID: 10219337]
Walterhouse DO Hoover ML Marymont MA Kletzel M High-dose chemotherapy followed by peripheral blood stem cell rescue for metastatic rhabdomyosarcoma: the experience at Chicago Children's Memorial Hospital. Med Pediatr Oncol . 1999 Feb;32(2):88-92
[PubMed ID: 9950194]
Loh K Matthay KK Hoover M Bracho FA Cortez AB Conte FA Albanese CT Miller TR Price DC Flores AJ Kaviani A Shoback D Hypercalcemia in malignant paraganglioma due to parathyroid hormone-related protein. Horm Res . 1998;50(4):217-21
[PubMed ID: 9838243]
Cohn SL Moss TJ Hoover M Katzenstein HM Haut PR Morgan ER Green AA Kletzel M Treatment of poor-risk neuroblastoma patients with high-dose chemotherapy and autologous peripheral stem cell rescue. Bone Marrow Transplant . 1997 Oct;20(7):543-51
[PubMed ID: 9337055]
Hoover M Morgan ER Kletzel M Prior fungal infection is not a contraindication to bone marrow transplant in patients with acute leukemia. Med Pediatr Oncol . 1997 Apr;28(4):268-73
[PubMed ID: 9078323]