Kenneth B. DeSantes, MD close

Kenneth B. DeSantes, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Kenneth De Santes completed his general pediatric training at Children's Hospital of Los Angeles and his pediatric hematology/oncology training at Children's Hospital and Medical Center, and the Fred Hutchinson Cancer Research Center in Seattle. He worked in the division of Bone Marrow Transplantation at the University of California, San Francisco for seven years before accepting a faculty position at the University of Wisconsin.


Dr. De Santes is the Clinical Director of the Pediatric Hematology/Oncology program, and Director of the Hematopoietic Stem Cell Transplant program at the American Family Children’s Hospital. He is a member of the American Pediatric Society, the American Society of Pediatric Hematology and Oncology, the American Society of Blood and Marrow Transplantation, the Children’s Oncology Group, and the Pediatric Blood and Marrow Transplant Consortium. Dr. De Santes also serves as a consultant for Best Doctors®, and the Chartwell Medical Advisory Board. He has written six book chapters and published over 30 research articles. His research interests include the treatment of neuroblastoma, and the use of immunotherapy and stem cell transplantation to treat pediatric cancer.


Pediatric Hematology and Oncology

Acute Lymphoblastic Leukemia

Acute Myeloid Leukemia

Adrenocortical carcinoma

Aplastic Anemia



Atypical Teratoid/Rhabdoid tumor

Bone Marrow Biopsy

Brain Stem Glioma

CAR T-cell Therapy (Pediatric)


Chronic Myeloid Leukemia

Congenital Hemolytic Anemias


Cyclic Neutropenia

Diamond-Blackfan Syndrome

Endocrine Tumors


Ewing Sarcoma

Fanconi's Anemia

Germ Cell Tumors

Hemophagocytic Lymphohistiocytosis

Hemophilia A

Hemophilia B


Hereditary Spherocytosis

Hodgkin's Disease

I-131 MIBG (Metaiodobenzylguadine)

Immune Thrombocytopenc Purpura


Juvenile Myelomonocytic Leukemia

Kostmann Syndrome

Langerhans' Cell Histiocytosis

Lumbar Puncture


Myelodysplastic Syndromes



Neurocutaneous Syndrome


Non-Hodgkin Lymphomas

Optic Glioma


Paroxysmal Nocturnal Hemoglobinuria

Pediatric Bone Marrow Transplant

Pediatric Cancer

Pediatric Sickle Cell Disease




Shwachman-Diamond Syndrome

Sturge-Weber Syndrome

Thalassemia Syndromes


Thyroid Tumors

Tuberous Sclerosis

Vascular malformations

Von Willebrand Disease

VonHippel-Lindau Disease

Wilms Tumor


American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics

Professional Certifications and Education

Board Certification Pediatric Hematology-Oncology
Fellowship Children's Hospital and Medical Center, Seattle, WA
Residency Children's Hospital of Los Angeles, Los Angeles, CA
Internship Children's Hospital of Los Angeles, Los Angeles, CA
Medical School New York Medical College, New York, NY

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. De Santes' research interests are focused on the utilization of natural killer (NK) cells to treat a wide variety of pediatric malignancies and developing novel stem cell transplant protocols for children with recurrent leukemia and high-risk solid tumors. He also is establishing more effective ways to utilize I-131 MIBG therapy for children with neuroblastoma.