James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing


Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders


Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection



American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of South Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Barretto KT Brockman-Schneider RA Kuipers I Basnet S Bochkov YA Altman MC Jarjour NN Gern JE Esnault S Human Airway Epithelial Cells Express a Functional IL-5 Receptor. Allergy . 2020 Apr 4;
[PubMed ID: 32246831]
Erkkola R Turunen R Räisänen K Waris M Vuorinen T Laine M Tähtinen P Gern JE Bochkov YA Ruohola A Jartti T Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children. Pediatr Infect Dis J . 2020 Apr;39(4):283-286
[PubMed ID: 31876616]
Kloepfer KM Gern JE Ecological and individual data both indicate that influenza inhibits rhinovirus infection. Proc Natl Acad Sci U S A . 2020 Mar 31;117(13):6987
[PubMed ID: 32127484]
Agache I Song Y Rocha C Beltran J Posso M Steiner C Alonso-Coello P Akdis C Akdis M Canonica GW Casale T Chivato T Corren J Del Giacco S Eiwegger T Firinu D Gern JE Hamelmann E Hanania N Mäkelä M Martín IH Nair P O'Mahony L Papadopoulos NG Papi A Park HS Pérez de Llano L Quirce S Sastre J Shamji M Schwarze J Canelo-Aybar C Palomares O Jutel M Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines-Recommendations on the use of biologicals in severe asthma. Allergy . 2020 Mar 10;
[PubMed ID: 32154939]
Mathioudakis AG Custovic A Deschildre A Ducharme FM Kalayci O Murray C Garcia AN Phipatanakul W Price D Sheikh A Agache I Bacharier L Bonini M Castro-Rodriguez JA De Carlo G Craig T Diamant Z Feleszko W Ierodiakonou D Gern JE Grigg J Hedlin G Hossny EM Jartti T Kaplan A Lemanske RF Le Souef P Makela MJ Matricardi PM Miligkos M Morais-Almeida M Pite H Pitrez PMC Pohunek P Roberts G Sanchez-Garcia S Tsiligianni I Turner S Winders TA Wong G Xepapadaki P Zar HJ Papadopoulos NG Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank. J Allergy Clin Immunol Pract . 2020 Mar 4;
[PubMed ID: 32146166]
Parikh V Scala J Patel R Corbi C Lo D Bochkov YA Kennedy JL Kurten RC Liggett SB Gern JE Koziol-White CJ Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle. Am J Respir Cell Mol Biol . 2020 Mar;62(3):310-318
[PubMed ID: 31533004]
Wiesner DL Merkhofer RM Ober C Kujoth GC Niu M Keller NP Gern JE Brockman-Schneider RA Evans MD Jackson DJ Warner T Jarjour NN Esnault SJ Feldman MB Freeman M Mou H Vyas JM Klein BS Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe . 2020 Feb 27;
[PubMed ID: 32130954]
Liu Y Bochkov YA Eickhoff JC Hu T Zumwalde NA Tan JW Lopez C Fichtinger PS Reddy TR Overmyer KA Gumperz JE Coon J Mathur SK Gern JE Smith JA Orosomucoid Like 3 (ORMDL3) Supports Rhinovirus Replication in Human Epithelial Cells. Am J Respir Cell Mol Biol . 2020 Feb 20;
[PubMed ID: 32078788]
Nakagome K Shimizu T Bochkov YA Noguchi T Kobayashi T Soma T Ueki S Gern JE Nagata M Cadherin-related family member 3 upregulates the effector functions of eosinophils. Allergy . 2020 Feb 13;
[PubMed ID: 32056219]
Agache I Beltran J Akdis C Akdis M Canelo-Aybar C Canonica GW Casale T Chivato T Corren J Del Giacco S Eiwegger T Firinu D Gern JE Hamelmann E Hanania N Mäkelä M Martín IH Nair P O'Mahony L Papadopoulos NG Papi A Park HS Pérez de Llano L Posso M Rocha C Quirce S Sastre J Shamji M Song Y Steiner C Schwarze J Alonso-Coello P Palomares O Jutel M Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. Allergy . 2020 Feb 8;
[PubMed ID: 32034960]
Denlinger LC Heymann P Lutter R Gern JE Exacerbation-Prone Asthma. J Allergy Clin Immunol Pract . 2020 Feb;8(2):474-482
[PubMed ID: 31765853]
Bergroth E Aakula M Elenius V Remes S Piippo-Savolainen E Korppi M Piedra PA Bochkov YA Gern JE Camargo CA Jr Jartti T Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma. J Allergy Clin Immunol Pract . 2020 Feb;8(2):588-595.e4
[PubMed ID: 31520837]
Xu L Gong Y Gern JE Lucey JA Influence of whey protein hydrolysis in combination with dextran glycation on immunoglobulin E binding capacity with blood sera obtained from patients with a cow milk protein allergy. J Dairy Sci . 2020 Feb;103(2):1141-1150
[PubMed ID: 31785876]
Jackson DJ Bacharier LB Calatroni A Gill MA Hu J Liu AH Wheatley LM Gern JE Gruchalla RS Khurana Hershey GK Kattan M Kercsmar CM Kim H O'Connor GT Patel S Pongracic JA Wood RA Busse WW Serum IL-6: A biomarker in childhood asthma? J Allergy Clin Immunol . 2020 Jan 28;
[PubMed ID: 32004524]
Altman MC Beigelman A Ciaccio C Gern JE Heymann PW Jackson DJ Kennedy JL Kloepfer K Lemanske RF Jr McWilliams LM Muehling L Nance C Peebles RS Jr Evolving concepts in how viruses impact asthma. J Allergy Clin Immunol . 2020 Jan 9;
[PubMed ID: 31926183]
McCauley K Durack J Valladares R Fadrosh DW Lin DL Calatroni A LeBeau PK Tran HT Fujimura KE LaMere B Merana G Lynch K Cohen RT Pongracic J Khurana Hershey GK Kercsmar CM Gill M Liu AH Kim H Kattan M Teach SJ Togias A Boushey HA Gern JE Jackson DJ Lynch SV National Institute of Allergy and Infectious Diseases–sponsored Inner-City Asthma Consortium. Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma. J Allergy Clin Immunol . 2019 Nov;144(5):1187-1197
[PubMed ID: 31201890]
DeMuri GP Eickhoff JC Gern JC Wald ER Clinical and Virological Characteristics of Acute Sinusitis in Children. Clin Infect Dis . 2019 Oct 30;69(10):1764-1770
[PubMed ID: 30649261]
Cuthbertson L Oo SWC Cox MJ Khoo SK Cox DW Chidlow G Franks K Prastanti F Borland ML Gern JE Smith DW Bizzintino JA Laing IA Le Souëf PN Moffatt MF Cookson WOC Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children. PLoS One . 2019;14(10):e0223990
[PubMed ID: 31622414]
Basnet S Bochkov YA Brockman-Schneider RA Kuipers I Aesif SW Jackson DJ Lemanske RF Jr Ober C Palmenberg AC Gern JE <i>CDHR3</i> Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections. Am J Respir Cell Mol Biol . 2019 Oct;61(4):450-458
[PubMed ID: 30916989]
Pomés A Glesner J Calatroni A Visness CM Wood RA O'Connor GT Kattan M Bacharier LB Wheatley LM Gern JE Busse WW National Institute of Allergy and Infectious Diseases–funded Inner-City Asthma Consortium. Cockroach allergen component analysis of children with or without asthma and rhinitis in an inner-city birth cohort. J Allergy Clin Immunol . 2019 Oct;144(4):935-944
[PubMed ID: 31201891]