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James E. Gern, MD
 

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.

Specialties

Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing

Asthma

Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders

Immunotherapy

Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection

Uticaria

Clinics

American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Pediatrics
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of South Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.


PubMed Articles
Helling BA Sobreira DR Hansen GT Sakabe NJ Luo K Billstrand C Laxman B Nicolae RI Nicolae DL Bochkov YA Gern JE Nobrega MA White SR Ober C Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma. Commun Biol . 2020 Nov 13;3(1):678
[PubMed ID: 33188283]
Raita Y Camargo CA Jr Bochkov YA Celedón JC Gern JE Mansbach JM Rhee EP Freishtat RJ Hasegawa K Integrated-omics endotyping of infants with rhinovirus bronchiolitis and risk of childhood asthma. J Allergy Clin Immunol . 2020 Nov 13;
[PubMed ID: 33197460]
Jackson DJ Busse WW Togias A Gern JE Altman MC Reply. J Allergy Clin Immunol . 2020 Nov;146(5):1214-1215
[PubMed ID: 32828589]
Tang HHF Lang A Teo SM Judd LM Gangnon R Evans MD Lee KE Vrtis R Holt PG Lemanske RF Jr Jackson DJ Holt KE Inouye M Gern JE Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk. J Allergy Clin Immunol . 2020 Oct 19;
[PubMed ID: 33091409]
Sheehan WJ Krouse RZ Calatroni A Gergen PJ Gern JE Gill MA Gruchalla RS Khurana Hershey GK Kattan M Kercsmar CM Lamm CI Little FF Makhija MM Searing DA Zoratti E Busse WW Teach SJ NIAID-sponsored Inner-City Asthma Consortium. Aeroallergen Sensitization, Serum IgE, and Eosinophilia as Predictors of Response to Omalizumab Therapy During the Fall Season Among Children with Persistent Asthma. J Allergy Clin Immunol Pract . 2020 Oct;8(9):3021-3028.e2
[PubMed ID: 32376491]
McKennan C Naughton K Stanhope C Kattan M O'Connor GT Sandel MT Visness CM Wood RA Bacharier LB Beigelman A Lovinsky-Desir S Togias A Gern JE Nicolae D Ober C Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels. Epigenetics . 2020 Sep 30;:1-15
[PubMed ID: 32997571]
Fujiogi M Camargo CA Jr Raita Y Bochkov YA Gern JE Mansbach JM Piedra PA Hasegawa K Association of rhinovirus species with nasopharyngeal metabolome in bronchiolitis infants: A multicenter study. Allergy . 2020 Sep;75(9):2379-2383
[PubMed ID: 32306415]
Gern JE Immune responses to rhinoviruses and asthma: Are we 3 steps closer to the door? J Allergy Clin Immunol . 2020 Sep;146(3):513-514
[PubMed ID: 32673613]
Papadopoulos NG Custovic A Deschildre A Mathioudakis AG Phipatanakul W Wong G Xepapadaki P Agache I Bacharier L Bonini M Castro-Rodriguez JA Chen Z Craig T Ducharme FM El-Sayed ZA Feleszko W Fiocchi A Garcia-Marcos L Gern JE Goh A Gómez RM Hamelmann EH Hedlin G Hossny EM Jartti T Kalayci O Kaplan A Konradsen J Kuna P Lau S Le Souef P Lemanske RF Mäkelä MJ Morais-Almeida M Murray C Nagaraju K Namazova-Baranova L Garcia AN Yusuf OM Pitrez PMC Pohunek P Pozo Beltrán CF Roberts GC Valiulis A Zar HJ Pediatric Asthma in Real Life Collaborators. Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden. J Allergy Clin Immunol Pract . 2020 Sep;8(8):2592-2599.e3
[PubMed ID: 32561497]
Forno E Bacharier LB Phipatanakul W Guilbert TW Cabana MD Ross K Covar R Gern JE Rosser FJ Blatter J Durrani S Han YY Wisniewski SR Celedón JC Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial. JAMA . 2020 Aug 25;324(8):752-760
[PubMed ID: 32840597]
Barretto KT Brockman-Schneider RA Kuipers I Basnet S Bochkov YA Altman MC Jarjour NN Gern JE Esnault S Human airway epithelial cells express a functional IL-5 receptor. Allergy . 2020 Aug;75(8):2127-2130
[PubMed ID: 32246831]
Steiman CA Evans MD Lee KE Lasarev MR Gangnon RE Olson BF Barnes KL Bendixsen CG Seroogy CM Gern JE Patterns of farm exposure are associated with reduced incidence of atopic dermatitis in early life. J Allergy Clin Immunol . 2020 Jul 7;
[PubMed ID: 32650021]
Vogt MR Fu J Kose N Williamson LE Bombardi R Setliff I Georgiev IS Klose T Rossmann MG Bochkov YA Gern JE Kuhn RJ Crowe JE Jr Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol . 2020 Jul 3;5(49)
[PubMed ID: 32620559]
Nakagome K Shimizu T Bochkov YA Noguchi T Kobayashi T Soma T Ueki S Gern JE Nagata M Cadherin-related family member 3 upregulates the effector functions of eosinophils. Allergy . 2020 Jul;75(7):1805-1809
[PubMed ID: 32056219]
Jackson DJ Busse WW Bacharier LB Kattan M O'Connor GT Wood RA Visness CM Durham SR Larson D Esnault S Ober C Gergen PJ Becker P Togias A Gern JE Altman MC Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol . 2020 Jul;146(1):203-206.e3
[PubMed ID: 32333915]
Mansbach JM Geller RJ Hasegawa K Piedra PA Avadhanula V Gern JE Bochkov YA Espinola JA Sullivan AF Camargo CA Detection of respiratory syncytial virus or rhinovirus weeks after hospitalization for bronchiolitis and the risk of recurrent wheezing. J Infect Dis . 2020 Jun 20;
[PubMed ID: 32564083]
Agache I Akdis C Akdis M Canonica GW Casale T Chivato T Corren J Chu DK Del Giacco S Eiwegger T Flood B Firinu D Gern JE Hamelmann E Hanania N Hernández-Martín I Knibb R Mäkelä M Nair P O'Mahony L Papadopoulos NG Papi A Park HS Pérez de Llano L Pfaar O Quirce S Sastre J Shamji M Schwarze J Palomares O Jutel M EAACI Biologicals Guidelines-Recommendations for severe asthma. Allergy . 2020 Jun 2;
[PubMed ID: 32484954]
Liu Y Bochkov YA Eickhoff JC Hu T Zumwalde NA Tan JW Lopez C Fichtinger PS Reddy TR Overmyer KA Gumperz JE Coon J Mathur SK Gern JE Smith JA Orosomucoid-like 3 Supports Rhinovirus Replication in Human Epithelial Cells. Am J Respir Cell Mol Biol . 2020 Jun;62(6):783-792
[PubMed ID: 32078788]
Jackson DJ Bacharier LB Calatroni A Gill MA Hu J Liu AH Wheatley LM Gern JE Gruchalla RS Khurana Hershey GK Kattan M Kercsmar CM Kim H O'Connor GT Patel S Pongracic JA Wood RA Busse WW Serum IL-6: A biomarker in childhood asthma? J Allergy Clin Immunol . 2020 Jun;145(6):1701-1704.e3
[PubMed ID: 32004524]
Mathioudakis AG Custovic A Deschildre A Ducharme FM Kalayci O Murray C Garcia AN Phipatanakul W Price D Sheikh A Agache I Bacharier L Bonini M Castro-Rodriguez JA De Carlo G Craig T Diamant Z Feleszko W Ierodiakonou D Gern JE Grigg J Hedlin G Hossny EM Jartti T Kaplan A Lemanske RF Le Souef P Makela MJ Matricardi PM Miligkos M Morais-Almeida M Pite H Pitrez PMC Pohunek P Roberts G Sanchez-Garcia S Tsiligianni I Turner S Winders TA Wong G Xepapadaki P Zar HJ Papadopoulos NG Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank. J Allergy Clin Immunol Pract . 2020 Jun;8(6):1953-1960.e9
[PubMed ID: 32146166]