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James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing


Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders


Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection



West Clinic
(608) 263-6180 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of Southern Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Cox DW Khoo SK Zhang G Lindsay K Keil AD Knight G Gern JE Laing IA Bizzintino J Le Souëf PN Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions. Eur Respir J . 2018 Aug;52(2)
[PubMed ID: 29976655]
Bacharier LB Beigelman A Calatroni A Jackson DJ Gergen PJ O'Connor GT Kattan M Wood RA Sandel MT Lynch SV Fujimura KE Fadrosh DW Santee CA Boushey H Visness CM Gern JE NIAID sponsored Inner-City Asthma Consortium. Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort. Am J Respir Crit Care Med . 2018 Aug 4;
[PubMed ID: 30079758]
Altman MC Gern JE Reply. J Allergy Clin Immunol . 2018 Aug;142(2):713
[PubMed ID: 29945814]
Xu L Gong Y Gern JE Ikeda S Lucey JA Glycation of whey protein with dextrans of different molar mass: Effect on immunoglobulin E-binding capacity with blood sera obtained from patients with cow milk protein allergy. J Dairy Sci . 2018 Aug;101(8):6823-6834
[PubMed ID: 29778476]
Hasegawa K Jartti T Bochkov YA Gern JE Mansbach JM Piedra PA Toivonen L Camargo CA Jr Rhinovirus Species in Children with Severe Bronchiolitis: Multicenter Cohort Studies in the US and Finland. Pediatr Infect Dis J . 2018 Jul 11;
[PubMed ID: 30001231]
Thompson EE Nicodemus-Johnson J Kim KW Gern JE Jackson DJ Lemanske RF Ober C Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes. Clin Epigenetics . 2018;10:62
[PubMed ID: 29760811]
Gill MA Liu AH Calatroni A Krouse RZ Shao B Schiltz A Gern JE Togias A Busse WW Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab. J Allergy Clin Immunol . 2018 May;141(5):1735-1743.e9
[PubMed ID: 28870461]
Brunwasser SM Gebretsadik T Gold DR Turi KN Stone CA Jr Datta S Gern JE Hartert TV A new model of wheezing severity in young children using the validated ISAAC wheezing module: A latent variable approach with validation in independent cohorts. PLoS One . 2018;13(4):e0194739
[PubMed ID: 29664908]
O'Connor GT Lynch SV Bloomberg GR Kattan M Wood RA Gergen PJ Jaffee KF Calatroni A Bacharier LB Beigelman A Sandel MT Johnson CC Faruqi A Santee C Fujimura KE Fadrosh D Boushey H Visness CM Gern JE Early-life home environment and risk of asthma among inner-city children. J Allergy Clin Immunol . 2018 Apr;141(4):1468-1475
[PubMed ID: 28939248]
Silkoff PE Flavin S Gordon R Loza MJ Sterk PJ Lutter R Diamant Z Turner RB Lipworth BJ Proud D Singh D Eich A Backer V Gern JE Herzmann C Halperin SA Mensinga TT Del Vecchio AM Branigan P San Mateo L Baribaud F Barnathan ES Johnston SL Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A randomized controlled study. J Allergy Clin Immunol . 2018 Apr;141(4):1220-1230
[PubMed ID: 28734844]
DeMuri GP Gern JE Eickhoff JC Lynch SV Wald ER Dynamics of Bacterial Colonization With Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis During Symptomatic and Asymptomatic Viral Upper Respiratory Tract Infection. Clin Infect Dis . 2018 Mar 19;66(7):1045-1053
[PubMed ID: 29121208]
Chandra S Wingender G Greenbaum JA Khurana A Gholami AM Ganesan AP Rosenbach M Jaffee K Gern JE Wood R O'Connor G Sandel M Kattan M Bacharier L Togias A Horner AA Kronenberg M Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment. J Immunol . 2018 Mar 15;200(6):1995-2003
[PubMed ID: 29431692]
Altman MC Whalen E Togias A O'Connor GT Bacharier LB Bloomberg GR Kattan M Wood RA Presnell S LeBeau P Jaffee K Visness CM Busse WW Gern JE Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol . 2018 Mar 5;
[PubMed ID: 29518416]
Bønnelykke K Coleman AT Evans MD Thorsen J Waage J Vissing NH Carlsson CJ Stokholm J Chawes BL Jessen LE Fischer TK Bochkov YA Ober C Lemanske RF Jr Jackson DJ Gern JE Bisgaard H Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses. Am J Respir Crit Care Med . 2018 Mar 1;197(5):589-594
[PubMed ID: 29121479]
Kattan M Bacharier LB O'Connor GT Cohen R Sorkness RL Morgan W Gergen PJ Jaffee KF Visness CM Wood RA Bloomberg GR Doyle S Burton R Gern JE Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy. J Allergy Clin Immunol Pract . 2018 Feb 13;
[PubMed ID: 29449165]
Bashir H Grindle K Vrtis R Vang F Kang T Salazar L Anderson E Pappas T Gangnon R Evans MD Jackson DJ Lemanske RF Jr Bochkov YA Gern JE Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. J Allergy Clin Immunol . 2018 Feb;141(2):822-824.e9
[PubMed ID: 29111214]
Kim CK Callaway Z Gern JE Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma. Allergy Asthma Immunol Res . 2018 Jan;10(1):12-17
[PubMed ID: 29178673]
Ludka-Gaulke T Ghera P Waring SC Keifer M Seroogy C Gern JE Kirkhorn S Farm exposure in early childhood is associated with a lower risk of severe respiratory illnesses. J Allergy Clin Immunol . 2018 Jan;141(1):454-456.e4
[PubMed ID: 28870458]
Barkal LJ Procknow CL �lvarez-García YR Niu M Jiménez-Torres JA Brockman-Schneider RA Gern JE Denlinger LC Theberge AB Keller NP Berthier E Beebe DJ Microbial volatile communication in human organotypic lung models. Nat Commun . 2017 Nov 24;8(1):1770
[PubMed ID: 29176665]
Gern JE Picornavectors. Viruses That Spread Bacteria. Am J Respir Crit Care Med . 2017 Nov 1;196(9):1095-1096
[PubMed ID: 28628339]