James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing


Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders


Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection



American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of Southern Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Hasegawa K Jartti T Bochkov YA Gern JE Mansbach JM Piedra PA Toivonen L Camargo CA Jr Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland. Pediatr Infect Dis J . 2019 Mar;38(3):e59-e62
[PubMed ID: 30001231]
Basnet S Palmenberg AC Gern JE Rhinoviruses and Their Receptors. Chest . 2019 Jan 17;
[PubMed ID: 30659817]
DeMuri GP Eickhoff JC Gern JC Wald ER Clinical and Virological Characteristics of Acute Sinusitis in Children. Clin Infect Dis . 2019 Jan 14;
[PubMed ID: 30649261]
Toivonen L Camargo CA Jr Gern JE Bochkov YA Mansbach JM Piedra PA Hasegawa K Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis. J Allergy Clin Immunol . 2019 Jan 14;
[PubMed ID: 30654045]
Davidson WF Leung DYM Beck LA Berin CM Boguniewicz M Busse WW Chatila TA Geha RS Gern JE Guttman-Yassky E Irvine AD Kim BS Kong HH Lack G Nadeau KC Schwaninger J Simpson A Simpson EL Spergel JM Togias A Wahn U Wood RA Woodfolk JA Ziegler SF Plaut M Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions". J Allergy Clin Immunol . 2019 Jan 9;
[PubMed ID: 30639346]
Bacharier LB Beigelman A Calatroni A Jackson DJ Gergen PJ O'Connor GT Kattan M Wood RA Sandel MT Lynch SV Fujimura KE Fadrosh DW Santee CA Boushey H Visness CM Gern JE NIAID sponsored Inner-City Asthma Consortium. Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort. Am J Respir Crit Care Med . 2019 Jan 1;199(1):71-82
[PubMed ID: 30079758]
Stubbendieck RM May DS Chevrette MG Temkin MI Wendt-Pienkowski E Cagnazzo J Carlson CM Gern JE Currie CR Competition among nasal bacteria suggests a role for siderophore-mediated interactions in shaping the human nasal microbiota. Appl Environ Microbiol . 2018 Dec 21;
[PubMed ID: 30578265]
Shen ZJ Hu J Kashi V Bochkov YA Gern JE Malter JS TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1. J Immunol . 2018 Dec 15;201(12):3503-3513
[PubMed ID: 30397031]
Agache I Miller R Gern JE Hellings PW Jutel M Muraro A Phipatanakul W Quirce S Peden D Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma. Allergy . 2018 Dec 4;
[PubMed ID: 30515837]
Altman MC Whalen E Togias A O'Connor GT Bacharier LB Bloomberg GR Kattan M Wood RA Presnell S LeBeau P Jaffee K Visness CM Busse WW Gern JE Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol . 2018 Dec;142(6):1856-1866
[PubMed ID: 29518416]
Gern JE Lee WM Swenson CA Nakagome K Lee I Wolff M Grindle K Sigelman S Liggett SB Togias A Evans M Denlinger L Gangnon R Bochkov YA Crisafi G Development of a Rhinovirus Inoculum using a Reverse Genetics Approach. J Infect Dis . 2018 Nov 1;
[PubMed ID: 30383246]
Tang HH Teo SM Belgrave DC Evans MD Jackson DJ Brozynska M Kusel MM Johnston SL Gern JE Lemanske RF Simpson A Custovic A Sly PD Holt PG Holt KE Inouye M Trajectories of childhood immune development and respiratory health relevant to asthma and allergy. Elife . 2018 Oct 15;7
[PubMed ID: 30320550]
Tattersall MC Evans MD Korcarz CE Mitchell C Anderson E DaSilva DF Salazar LP Gern JE Jackson DJ Lemanske RF Jr Stein JH Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort. PLoS One . 2018;13(9):e0204708
[PubMed ID: 30261051]
Teo SM Tang HHF Mok D Judd LM Watts SC Pham K Holt BJ Kusel M Serralha M Troy N Bochkov YA Grindle K Lemanske RF Jr Johnston SL Gern JE Sly PD Holt PG Holt KE Inouye M Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease. Cell Host Microbe . 2018 Sep 12;24(3):341-352.e5
[PubMed ID: 30212648]
Togias A Gergen PJ Hu JW Babineau DC Wood RA Cohen RT Makhija MM Khurana Hershey GK Kercsmar CM Gruchalla RS Liu AH Wang E Kim H Lamm CI Bacharier LB Pillai D Sigelman SM Gern JE Busse WW Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes. J Allergy Clin Immunol . 2018 Sep 11;
[PubMed ID: 30213627]
Leino A Lukkarinen M Turunen R Vuorinen T Söderlund-Venermo M Vahlberg T Camargo CA Jr Bochkov YA Gern JE Jartti T Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing. Allergy . 2018 Aug 24;
[PubMed ID: 30144084]
Cox DW Khoo SK Zhang G Lindsay K Keil AD Knight G Gern JE Laing IA Bizzintino J Le Souëf PN Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions. Eur Respir J . 2018 Aug;52(2)
[PubMed ID: 29976655]
Altman MC Gern JE Reply. J Allergy Clin Immunol . 2018 Aug;142(2):713
[PubMed ID: 29945814]
Xu L Gong Y Gern JE Ikeda S Lucey JA Glycation of whey protein with dextrans of different molar mass: Effect on immunoglobulin E-binding capacity with blood sera obtained from patients with cow milk protein allergy. J Dairy Sci . 2018 Aug;101(8):6823-6834
[PubMed ID: 29778476]
Thompson EE Nicodemus-Johnson J Kim KW Gern JE Jackson DJ Lemanske RF Ober C Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes. Clin Epigenetics . 2018;10:62
[PubMed ID: 29760811]