James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing


Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders


Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection



American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of Southern Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Stubbendieck RM May DS Chevrette MG Temkin MI Wendt-Pienkowski E Cagnazzo J Carlson CM Gern JE Currie CR Competition among Nasal Bacteria Suggests a Role for Siderophore-Mediated Interactions in Shaping the Human Nasal Microbiota. Appl Environ Microbiol . 2019 May 15;85(10)
[PubMed ID: 30578265]
Schulten V Frazier A Calatroni A Kattan M Bacharier LB O'Connor GT Sandel MT Wood RA Wheatley LM Togias A Visness CM Dresen A Gern JE Sette A The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age. Clin Exp Allergy . 2019 May 2;
[PubMed ID: 31046157]
Basnet S Palmenberg AC Gern JE Rhinoviruses and Their Receptors. Chest . 2019 May;155(5):1018-1025
[PubMed ID: 30659817]
Toivonen L Camargo CA Jr Gern JE Bochkov YA Mansbach JM Piedra PA Hasegawa K Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis. J Allergy Clin Immunol . 2019 May;143(5):1925-1928.e7
[PubMed ID: 30654045]
Altman MC Gill MA Whalen E Babineau DC Shao B Liu AH Jepson B Gruchalla RS O'Connor GT Pongracic JA Kercsmar CM Khurana Hershey GK Zoratti EM Johnson CC Teach SJ Kattan M Bacharier LB Beigelman A Sigelman SM Presnell S Gern JE Gergen PJ Wheatley LM Togias A Busse WW Jackson DJ Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children. Nat Immunol . 2019 May;20(5):637-651
[PubMed ID: 30962590]
Altman MC Gern JE Reply. J Allergy Clin Immunol . 2019 Apr 9;
[PubMed ID: 30979657]
Hasegawa K Mansbach JM Bochkov YA Gern JE Piedra PA Bauer CS Teach SJ Wu S Sullivan AF Camargo CA Jr Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze. JAMA Pediatr . 2019 Apr 1;
[PubMed ID: 30933255]
Basnet S Bochkov YA Brockman-Schneider RA Kuipers I Aesif SW Jackson DJ Lemanske RF Jr Ober C Palmenberg AC Gern JE CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections. Am J Respir Cell Mol Biol . 2019 Mar 27;
[PubMed ID: 30916989]
Agache I Miller R Gern JE Hellings PW Jutel M Muraro A Phipatanakul W Quirce S Peden D Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document. Allergy . 2019 Mar;74(3):449-463
[PubMed ID: 30515837]
Leino A Lukkarinen M Turunen R Vuorinen T Söderlund-Venermo M Vahlberg T Camargo CA Jr Bochkov YA Gern JE Jartti T Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing. Allergy . 2019 Mar;74(3):518-526
[PubMed ID: 30144084]
Davidson WF Leung DYM Beck LA Berin CM Boguniewicz M Busse WW Chatila TA Geha RS Gern JE Guttman-Yassky E Irvine AD Kim BS Kong HH Lack G Nadeau KC Schwaninger J Simpson A Simpson EL Spergel JM Togias A Wahn U Wood RA Woodfolk JA Ziegler SF Plaut M Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions". J Allergy Clin Immunol . 2019 Mar;143(3):894-913
[PubMed ID: 30639346]
Togias A Gergen PJ Hu JW Babineau DC Wood RA Cohen RT Makhija MM Khurana Hershey GK Kercsmar CM Gruchalla RS Liu AH Wang E Kim H Lamm CI Bacharier LB Pillai D Sigelman SM Gern JE Busse WW Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes. J Allergy Clin Immunol . 2019 Mar;143(3):1003-1011.e10
[PubMed ID: 30213627]
Hasegawa K Jartti T Bochkov YA Gern JE Mansbach JM Piedra PA Toivonen L Camargo CA Jr Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland. Pediatr Infect Dis J . 2019 Mar;38(3):e59-e62
[PubMed ID: 30001231]
DeMuri GP Eickhoff JC Gern JC Wald ER Clinical and Virological Characteristics of Acute Sinusitis in Children. Clin Infect Dis . 2019 Jan 14;
[PubMed ID: 30649261]
Bacharier LB Beigelman A Calatroni A Jackson DJ Gergen PJ O'Connor GT Kattan M Wood RA Sandel MT Lynch SV Fujimura KE Fadrosh DW Santee CA Boushey H Visness CM Gern JE NIAID sponsored Inner-City Asthma Consortium. Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort. Am J Respir Crit Care Med . 2019 Jan 1;199(1):71-82
[PubMed ID: 30079758]
Negrey JD Reddy RB Scully EJ Phillips-Garcia S Owens LA Langergraber KE Mitani JC Emery Thompson M Wrangham RW Muller MN Otali E Machanda Z Hyeroba D Grindle KA Pappas TE Palmenberg AC Gern JE Goldberg TL Simultaneous outbreaks of respiratory disease in wild chimpanzees caused by distinct viruses of human origin. Emerg Microbes Infect . 2019;8(1):139-149
[PubMed ID: 30866768]
Shen ZJ Hu J Kashi V Bochkov YA Gern JE Malter JS TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1. J Immunol . 2018 Dec 15;201(12):3503-3513
[PubMed ID: 30397031]
Altman MC Whalen E Togias A O'Connor GT Bacharier LB Bloomberg GR Kattan M Wood RA Presnell S LeBeau P Jaffee K Visness CM Busse WW Gern JE Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol . 2018 Dec;142(6):1856-1866
[PubMed ID: 29518416]
Gern JE Lee WM Swenson CA Nakagome K Lee I Wolff M Grindle K Sigelman S Liggett SB Togias A Evans M Denlinger L Gangnon R Bochkov YA Crisafi G Development of a Rhinovirus Inoculum using a Reverse Genetics Approach. J Infect Dis . 2018 Nov 1;
[PubMed ID: 30383246]
Tang HH Teo SM Belgrave DC Evans MD Jackson DJ Brozynska M Kusel MM Johnston SL Gern JE Lemanske RF Simpson A Custovic A Sly PD Holt PG Holt KE Inouye M Trajectories of childhood immune development and respiratory health relevant to asthma and allergy. Elife . 2018 Oct 15;7
[PubMed ID: 30320550]