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Jacques Galipeau, MD close
Jacques Galipeau, MD

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Jacques Galipeau, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Galipeau is a board certified Hematologist with an interest in benign blood disorders, including diagnostic assessment of blood count and hematology laboratory abnormalities, congenital and acquired anemia, and autoimmune blood disorders.

Specialties

Hematology

Hematology (Leukemia, Lymphoma and Multiple Myeloma)

Hematology (non cancer)

Clinics

UW Carbone Cancer Center
(608) 265-1700 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Hematology
Fellowship

Hematology/Oncology, Tufts Medical Center, New England Medical Center Hospital, Boston, MA


Residency Jewish General Hospital, Montreal, Quebec, Canada
Internship Universite de Montreal, Montreal, Quebec, Canada
Medical School Universite de Montreal, Montreal, Quebec, Canada

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Galipeau is the Don and Marilyn Anderson Professor of Oncology within the Department of Medicine and UW Carbone Comprehensive Cancer Center at the University of Wisconsin-Madison, and the inaugural Assistant Dean for Therapeutics Discovery and Development at the UW School of Medicine and Public Health. Dr. Galipeau has initiated and developed an NIH-funded research program in the study and use of mesenchymal stromal cells as an immunotherapy of catastrophic illnesses including cancer and immune disease. He is an internationally-recognized expert in translational development of cell therapies and the sponsor of a series of FDA-sanctioned clinical trials examining the use of autologous, marrow-derived mesenchymal stromal cells for immune disorders, including Crohn's disease and graft versus host disease. He has also developed the field of fusion engineered cytokines, known as fusokines, as a novel pharmaceutical means of treating immune disorders and cancer. He is the director of the University of Wisconsin Advanced Cell Therapy Program, whose mission is to develop personalized cell therapies for immune and malignant disorders and to promote and deploy first-in-human clinical trials of cell therapy innovations to improve outcomes for children and adults.


PubMed Articles
Pennati A Asress S Glass JD Galipeau J Adoptive transfer of IL-10<sup>+</sup> regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model. Cell Mol Immunol . 2018 Jan 8;
[PubMed ID: 29307886]
Naskou MC Norton NA Copland IB Galipeau J Peroni JF Innate immune responses of equine monocytes cultured in equine platelet lysate. Vet Immunol Immunopathol . 2018 Jan;195:65-71
[PubMed ID: 29249319]
Rajan D Chinnadurai R Keefe EO Boyoglu-Barnum S Todd SO Hartert TV Galipeau J Anderson LJ Protective role of Indoleamine 2,3 dioxygenase in Respiratory Syncytial Virus associated immune response in airway epithelial cells. Virology . 2017 Dec;512:144-150
[PubMed ID: 28963880]
Lewis HC Chinnadurai R Bosinger SE Galipeau J The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells. Oncotarget . 2017 Nov 3;8(54):91914-91927
[PubMed ID: 29190885]
Conklin LS Hanley PJ Galipeau J Barrett J Bollard CM Intravenous mesenchymal stromal cell therapy for inflammatory bowel disease: Lessons from the acute graft versus host disease experience. Cytotherapy . 2017 Jun;19(6):655-667
[PubMed ID: 28433516]
Stenger EO Chinnadurai R Yuan S Garcia M Arafat D Gibson G Krishnamurti L Galipeau J Bone Marrow-Derived Mesenchymal Stromal Cells from Patients with Sickle Cell Disease Display Intact Functionality. Biol Blood Marrow Transplant . 2017 May;23(5):736-745
[PubMed ID: 28132869]
Galipeau J Reply: "Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-γ Prelicensing Is Context Dependent". Stem Cells . 2017 May;35(5):1440-1441
[PubMed ID: 27758017]
Chinnadurai R Rajan D Ng S McCullough K Arafat D Waller EK Anderson LJ Gibson G Galipeau J Immune dysfunctionality of replicative senescent mesenchymal stromal cells is corrected by IFNγ priming. Blood Adv . 2017 Apr 25;1(11):628-643
[PubMed ID: 28713871]
Deng J Li Y Pennati A Yuan S Wu JH Waller EK Galipeau J GM-CSF and IL-4 Fusion Cytokine Induces B Cell-Dependent Hematopoietic Regeneration. Mol Ther . 2017 Feb 1;25(2):416-426
[PubMed ID: 28153092]
Pennati A Ng S Wu Y Murphy JR Deng J Rangaraju S Asress S Blanchfield JL Evavold B Galipeau J Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation. J Neurosci . 2016 Dec 14;36(50):12598-12610
[PubMed ID: 27821578]
Ng S Deng J Chinnadurai R Yuan S Pennati A Galipeau J Stimulation of Natural Killer Cell-Mediated Tumor Immunity by an IL15/TGFβ-Neutralizing Fusion Protein. Cancer Res . 2016 Oct 1;76(19):5683-5695
[PubMed ID: 27488533]
Dhere T Copland I Garcia M Chiang KY Chinnadurai R Prasad M Galipeau J Kugathasan S The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease - a phase 1 trial with three doses. Aliment Pharmacol Ther . 2016 Sep;44(5):471-81
[PubMed ID: 27385373]
Chinnadurai R Copland IB Garcia MA Petersen CT Lewis CN Waller EK Kirk AD Galipeau J Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing. Stem Cells . 2016 Sep;34(9):2429-42
[PubMed ID: 27299362]
Deng J Park D Wang M Nooka A Deng Q Matulis S Kaufman J Lonial S Boise LH Galipeau J Deng X BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth. Oncotarget . 2016 May 10;7(19):27753-63
[PubMed ID: 27049723]
Robinson ST Douglas AM Chadid T Kuo K Rajabalan A Li H Copland IB Barker TH Galipeau J Brewster LP A novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization. Acta Biomater . 2016 May;36:86-98
[PubMed ID: 26961805]
Deng J Pennati A Cohen JB Wu Y Ng S Wu JH Flowers CR Galipeau J GIFT4 fusokine converts leukemic B cells into immune helper cells. J Transl Med . 2016 Apr 27;14(1):106
[PubMed ID: 27118475]
Stenger EO Krishnamurti L Galipeau J Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation. BMC Immunol . 2015 Dec 16;16:74
[PubMed ID: 26674007]
Feng H Zhang H Deng J Wang L He Y Wang S Seyedtabaei R Wang Q Liu L Galipeau J Compans RW Wang BZ Incorporation of a GPI-anchored engineered cytokine as a molecular adjuvant enhances the immunogenicity of HIV VLPs. Sci Rep . 2015 Jul 7;5:11856
[PubMed ID: 26150163]
Chinnadurai R Copland IB Ng S Garcia M Prasad M Arafat D Gibson G Kugathasan S Galipeau J Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy. Mol Ther . 2015 Jul;23(7):1248-1261
[PubMed ID: 25899824]
Hsieh J Ng S Bosinger S Wu JH Tharp GK Garcia A Hossain MS Yuan S Waller EK Galipeau J A GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiency. Clin Transl Immunology . 2015 May;4(5):e37
[PubMed ID: 26131365]