HIV Prevention: Pre-Exposure Prophylaxis (PrEP)

HIV/AIDS Comprehensive Care Program Contact Information

(608) 263-0946

The UW Health HIV/AIDS Comprehensive Care Program is committed to preventing HIV infection. Therefore, we offer Pre-exposure Prophylaxis (PrEP) and Post-exposure Prophylaxis (PEP) services to help individuals prevent HIV infection.


Pre-exposure Prophlaxis (PrEP) is when an individual at higher risk for HIV takes HIV medicines daily to lower their chances of getting infected. It is highly effective for preventing HIV if used as prescribed. A person taking PrEP must be tested for HIV and have certain labs drawn regularly to monitor their health status.


Post-exposure Prophylaxis (PEP) is when a person who may have been exposed to HIV in the last 72 hours takes HIV medicines daily for 28 days to lower their chances of getting infected. The sooner the person starts PEP the better. PEP should be used in emergency situations. If you are at high risk for HIV, you should consider taking daily PrEP to prevent HIV.


Medicaid, Medicare, and most insurance covers the costs of PrEP and PEP; however, the Ryan White program and the AIDS Drug Assistance Program (ADAP) do not. Some patients may be eligible for pharmaceutical manufacturer assistance programs to help with medication costs or copays.


HIV Biomedical Prevention: PrEP and PEP

  • PEP line and PrEP Line - Rapid, up-to-date clinical telephone consultation for PrEP and PEP decision-making
  • PEP 101 – Explains how PEP (Post-Exposure prophylaxis) works to prevent HIV infection after being potentially exposed to HIV
  • PrEP 101 - Explains what PrEP (Pre-Exposure prophylaxis) is, how it works to prevent HIV infection, and answers frequently asked questions about PrEP
  • PrEP - Specific information on PrEP tailored to specific populations
  • What is PrEP? - Short video with information about PrEP and how it can work inside the body to prevent HIV infection
  • PrEP in Wisconsin - Information on getting, and paying for, PrEP in Wisconsin
  • National Alliance of State and Territorial AIDS Directors (NASTAD) fact sheet on patient assistance programs