Corticosteroids (such as prednisone or dexamethasone) are referred to as "transitional" medicines for the treatment of cluster headaches, because they are sometimes used to break a cycle of cluster headaches. They are paired with medicines that stop (abortive) or prevent (prophylactic) additional headaches during a headache cycle. Often, within 2 to 4 days after starting treatment with corticosteroids, you will become headache-free. By the time the corticosteroids are stopped—their use is often tapered within 6 to 8 weeks of starting and then discontinued—the medicines used to prevent cluster headaches, such as verapamil, have taken effect.
Corticosteroids are not used over a long period of time because they can cause serious side effects, including:
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
Primary Medical Reviewer Anne C. Poinier, MD - Internal Medicine
Adam Husney, MD - Family Medicine
Martin J. Gabica, MD - Family Medicine
Specialist Medical Reviewer Colin Chalk, MD, CM, FRCPC - Neurology
Current as ofOctober 14, 2016
To learn more about Healthwise, visit Healthwise.org.
© 1995-2017 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Donations to UW Health are managed by the University of Wisconsin Foundation, a publicly supported charitable organization under 501(c)(3) of the Internal Revenue Code.