National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Trisomy X is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms Back to top
- 47, XXX
- 47, XXX karyotype
- 47, XXX syndrome
- triple X syndrome
- triplo X
- XXX syndrome
Disorder Subdivisions Back to top
General Discussion Back to top
Trisomy X is a disorder that affects females and is characterized by the presence of an additional X chromosome. Normally, females have two X chromosomes; however, females with trisomy X carry three X chromosomes in the nuclei of body cells. There are specific physical features (phenotype) associated with this chromosomal disorder. Common symptoms that can potentially occur include language-based learning disabilities, developmental dyspraxia, tall stature, low muscle tone (hypotonia), and abnormal bending or curving of the pinkies toward the ring fingers (clinodactyly). Trisomy X occurs randomly as a result from errors during the division of reproductive cells in one of the parents. This disorder occurs in one in 900 to 1,000 live births.
Resources Back to top
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
National Dissemination Center for Children with Disabilities
1825 Connecticut Ave NW, Suite 700
Washington, D.C. 20009
National Center for Learning Disabilities
381 Park Avenue South
New York, NY 10016
Chromosome Disorder Outreach, Inc.
P.O. Box 724
Boca Raton, FL 33429-0724
Learning Disabilities Association of America
4156 Library Road
Pittsburgh, PA 15234-1349
International Dyslexia Association
40 York Rd
Baltimore, MD 21204
UNIQUE - Rare Chromosome Disorder Support Group
P.O. Box 2189
Surrey, Intl CR3 5GN
Tel: 44 0 1883 330766
Fax: 44 0 1883 330766
MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
PO Box 241956
Los Angeles, CA 90024
Klinefelter Syndrome & Associates
P.O. Box 461047
Aurora, CO 80046-1047
Focus Foundation, Inc.
PO Box 190
Davidsonville, MD 21035
For a Complete Report Back to top
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 2/11/2011
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