National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Leiomyosarcoma is not the name you expected.
Leiomyosarcoma is a malignant (cancerous) tumor that arises from smooth muscle Cells There are essentially two types of muscles in the body - voluntary and involuntary. Smooth muscles are involuntary muscles - the brain has no conscious control over them. Smooth muscles react involuntarily in response to various stimuli. For example, smooth muscle that lines the walls of the digestive tract causes wave-like contractions (peristalsis) that aid in the digestion and transport of food. Smooth muscles in the salivary glands cause the glands to squirt saliva into the mouth in response to taking a bite of food. Smooth muscle in the skin causes goose bumps to form in response to cold.
Leiomyosarcoma is a form of cancer. The term "cancer" refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant body sites via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including leiomyosarcomas, may be classified based upon the cell type involved, the specific nature of the malignancy, and the disease's clinical course. Leiomyosa usually spreads via the bloodstream. It is very rare to see it in lymphatics.
Since smooth muscle is found all over the body, a leiomyosarcoma can form almost anywhere where there are blood vessels, heart, liver, pancreas, genitourinary and gastrointestinal tract, the space behind the abdominal cavity (retroperitoneum), uterus, skin. The uterus is the most common location for a leiomyosarcoma. Most leiomyosarcomas of the gastrointestinal tract are now reclassified as gastrointestinal stromal tumors (GIST - see below)
Leiomyosarcoma is classified as a soft tissue sarcoma. Sarcomas are malignant tumors that arise from the connective tissue, which connects, supports and surrounds various structures and organs in the body. Soft tissue includes fat, muscle, nerves, tendons, and blood and lymph vessels. The exact cause of leiomyosarcoma, including uterine leiomyosarcoma, is unknown.
American Cancer Society, Inc.
- 250 Williams NW St
- Ste 6000
- Atlanta, GA 30303
- Tel: (404)320-3333
- Tel: (800)227-2345
- Website: http://www.cancer.org
- 76 Ellsworth Street
- San Francisco, CA 94110
- Tel: (415)826-0474
- Email: firstname.lastname@example.org
- Website: http://www.beatsarcoma.org/
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
National Cancer Institute
- 6116 Executive Blvd Suite 300
- Bethesda, MD 20892-8322
- Tel: (301)435-3848
- Tel: (800)422-6237
- Email: email@example.com
- Website: http://www.cancer.gov
Northwest Sarcoma Foundation
- P.O. Box 91460
- Portland, OR 97291
- Tel: (503)954-5740
- Email: firstname.lastname@example.org
- Website: http://www.nwsarcoma.org
OncoLink: The University of Pennsylvania Cancer Center Resource
- 3400 Spruce Street
- 2 Donner
- Philadelphia, PA 19104-4283
- Tel: (215)349-8895
- Fax: (215)349-5445
- Email: email@example.com
- Website: http://www.oncolink.upenn.edu
Rare Cancer Alliance
- 1649 North Pacana Way
- Green Valley, AZ 85614
- Website: http://www.rare-cancer.org
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- Mill Valley, CA 94941
- Tel: (415)381-7236
- Fax: (415)381-7235
- Email: firstname.lastname@example.org
- Website: http://www.sarcomaalliance.org
Sarcoma Foundation of America
- 9899 Main Street Ste 204
- Damascus, MD 20872
- Tel: (301)253-8687
- Fax: (301)253-8690
- Email: email@example.com
- Website: http://www.curesarcoma.org
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 12/16/1969
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