Central Diabetes Insipidus
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Central Diabetes Insipidus is not the name you expected.
Central diabetes insipidus (CDI) is a rare disorder characterized by excessive thirst (polydipsia) and excessive urination (polyuria). It is not related to the more common diabetes mellitus (sugar diabetes), in which the body does not produce or properly use insulin. CDI is a distinct disorder caused by complete or partial deficiency of the protein, arginine vasopressin (AVP), which is required by the kidneys to manage water balance in the body. If affected individuals do not have access to water, dehydration may occur. Eventually, more serious symptoms can develop including changes in consciousness and confusion associated with dehydration and elevation in serum sodium concentration (hypertonic dehydration). CDI may be caused by any condition that affects the creation, transport or release of vasopressin. CDI may be inherited or acquired. In some cases, no cause can be identified (idiopathic).
American Diabetes Association
- 1701 N. Beauregard Street
- Alexandria, VA 22311
- Tel: (703)549-1500
- Fax: (703)549-6995
- Tel: (800)342-2383
- Email: askADA@diabetes.org
- Website: http://www.diabetes.org
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
NIH/National Institute of Diabetes, Digestive & Kidney Diseases
- Office of Communications & Public Liaison
- Bldg 31, Rm 9A06
- Bethesda, MD 20892-2560
- Tel: (301)496-3583
- Email: NDDIC@info.niddk.nih.gov
- Website: http://www2.niddk.nih.gov/
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
Last Updated: 7/13/2015
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