Severe Combined Immunodeficiency
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Severe Combined Immunodeficiency is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Severe Combined Immunodeficiency (SCID) is a group of rare congenital syndromes characterized by little if any immune responses. This results in frequent recurring infections. Cellular immune responses involve specialized white blood cells known as T lymphocytes or "killer cells". These cells assist other white blood cells (B lymphocytes) to respond to infectious, foreign agents that invade the body (i.e., bacteria or viruses). The B lymphocytes maintain immunity by enabling the body to produce and preserve circulating antibodies.
People with Severe Combined Immunodeficiency are unusually susceptible to recurrent infections with bacteria, viruses, fungi, and other infectious agents that can be life-threatening.
There are several types of Severe Combined Immunodeficiencies. These include: Autosomal Recessive Severe Combined Immunodeficiency, X-Linked Recessive Severe Combined Immunodeficiency, Adenosine Deaminase Deficiency (ADA), Bare Lymphocyte Syndrome, Severe Combined Immunodeficiency with Leukopenia (Reticular Dysgenesis), and Swiss-type Agammaglobulinemia. Each type of Severe Combined Immune Deficiency is caused by a different genetic defect, but the primary symptom is reduced or absent immune functions, and all types are hereditary.
American Academy of Allergy, Asthma and Immunology
- 611 East Wells Street
- Milwaukee, WI 53202
- Tel: (414)272-6071
- Fax: (414)276-3349
- Tel: (800)822-2762
- Email: firstname.lastname@example.org
- Website: http://www.aaaai.org
European Society for Immunodeficiencies
- 1-3 rue de Chantepoulet
- Geneva, CH 1211
- Tel: 410229080484
- Fax: 41229069140
- Email: email@example.com
- Website: http://www.esid.org
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
Immune Deficiency Foundation
- 110 West Road
- Suite 300
- Towson, MD 21204
- Tel: (410)321-6647
- Fax: (410)321-9165
- Tel: (800)296-4433
- Email: firstname.lastname@example.org
- Website: http://www.primaryimmune.org
International Patient Organization for Primary Immunodeficiencies
- Firside Main Road
- Cornwall, PL11 3LE
- United Kingdom
- Tel: 441503250668
- Fax: 441503250961
- Email: email@example.com
- Website: http://www.ipopi.org/
March of Dimes Birth Defects Foundation
- 1275 Mamaroneck Avenue
- White Plains, NY 10605
- Tel: (914)997-4488
- Fax: (914)997-4763
- Website: http://www.marchofdimes.com
NIH/National Institute of Allergy and Infectious Diseases
- NIAID Office of Communications and Government Relations
- 5601 Fishers Lane, MSC 9806
- Bethesda, MD 20892-9806
- Tel: (301)496-5717
- Fax: (301)402-3573
- Tel: (866)284-4107
- Email: firstname.lastname@example.org
- Website: http://www.niaid.nih.gov/
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It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
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Last Updated: 12/13/1969
Copyright 2007 National Organization for Rare Disorders, Inc.
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