Skip to Content
UW Health SMPH
American Family Children's Hospital
DONATE Donate
SHARE TEXT

mecamylamine

Pronunciation: meck a MILL a meen

Brand: Inversine

What is the most important information I should know about mecamylamine?

Multum dizzy

Use caution when driving, operating machinery, or performing other hazardous activities. Mecamylamine may cause dizziness. If you experience dizziness, avoid these activities.

Multum dizzy

If you experience dizziness, rise slowly from a sitting or lying position to avoid falling.

Multum noalcohol

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking mecamylamine.

Take mecamylamine every day at the same time, usually after meals.

Call your doctor if you experience tremor, abdominal pain, abdominal distention, or diarrhea.

What is mecamylamine?

Mecamylamine is used to treat moderate to severe hypertension (high blood pressure). Because of its many side effects, mecamylamine is not commonly used.

Mecamylamine may also be used for purposes other than those listed in this medication guide.

Who should not take mecamylamine?

Before taking this medication, tell your doctor if you

  • have arteriosclerosis (poor blood flow in the arteries, or "hardening of the arteries") in your heart (coronary) or to the head (cerebral);
  • have recently had a heart attack;
  • have glaucoma;
  • have kidney disease; or
  • have difficulty urinating as a result of an enlarged prostate or some other cause.

You may not be able to take mecamylamine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Multum nopreg

Mecamylamine is in the FDA pregnancy category C. This means that it is not known whether mecamylamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

Multum nopreg

It is not known whether mecamylamine passes into breast milk. Do not take mecamylamine without first talking to your doctor if you are breast-feeding a baby.

How should I take mecamylamine?

Multum nocrush

Take mecamylamine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Multum water

Take each dose with a full glass of water.

Multum food

Take mecamylamine after meals.

Take each dose at the same time every day.

Multum donot

Do not stop taking this medication unless your doctor approves. Not taking your medication could make your condition much worse.

Multum rt

Store mecamylamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Multum emt

Seek emergency medical attention.

Symptoms of a mecamylamine overdose include fainting, dizziness, weakness, confusion, nausea, vomiting, diarrhea, constipation, difficulty urinating, anxiety, dry mouth, large pupils, blurred vision, and an irregular heartbeat.

What should I avoid while taking this mecamylamine?

Multum dizzy

Use caution when driving, operating machinery, or performing other hazardous activities. Mecamylamine may cause dizziness. If you experience dizziness, avoid these activities.

Multum dizzy

If you experience dizziness, rise slowly from a sitting or lying position to avoid falling.

Multum noalcohol

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking mecamylamine.

What are the possible side effects of mecamylamine?

Multum emt

If you experience any of the following serious side effects, stop taking mecamylamine and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
  • abdominal pain, abdominal distention, or diarrhea.

Other, less serious side effects may be more likely to occur. Continue to take mecamylamine and talk to your doctor if you experience

  • nausea, vomiting, or constipation;
  • dry mouth;
  • decreased appetite;
  • dizziness and fainting;
  • drowsiness or weakness;
  • dilated (large) pupils and blurred vision; or
  • difficulty urinating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mecamylamine?

Generally, mecamylamine should not be used during treatment with antibiotics or sulfa-based drugs. Tell your doctor if you are taking drugs of either of these types.

Other drugs used to lower high blood pressure may increase the effects of mecamylamine, and serious side effects could occur. Tell your doctor about all medicines you take to lower high blood pressure or to treat other heart conditions.

Anesthesia (use of drugs that put you to sleep for surgery) may also increase the effects of mecamylamine. Tell your doctor or dentist that you are taking mecamylamine before you have surgery.

Drugs other than those listed here may also interact with mecamylamine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has additional information about mecamylamine written for health professionals that you may read.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 2.07. Revision date: 12/15/2010.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.