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hydrochlorothiazide and moexipril

Pronunciation: hye droe klor oh THY a zide and moe EX a pril

Brand: Uniretic

HCTZ-Moexipril 12.5 mg-15 mg-COB

peanut, white, imprinted with K U, 720

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HCTZ-Moexipril 12.5 mg-15 mg-TEV

oblong, white, imprinted with 9 3, 5214

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HCTZ-Moexipril 12.5 mg-7.5 mg-COB

peanut, yellow, imprinted with K U, 712

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HCTZ-Moexipril 12.5 mg-7.5 mg-TEV

oblong, yellow, imprinted with 9 3, 5213

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HCTZ-Moexipril 25 mg-15 mg-COB

peanut, orange, imprinted with K U, 725

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HCTZ-Moexipril 25 mg-15 mg-TEV

oblong, yellow, imprinted with 9 3, 5215

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Uniretic 12.5 mg-15 mg

oval, white, imprinted with 720, S P

Image of Uniretic 12.5 mg-15 mg
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Uniretic 12.5 mg-7.5 mg

oval, yellow, imprinted with 712, S P

Image of Uniretic 12.5 mg-7.5 mg
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Uniretic 25 mg-15 mg

oval, yellow, imprinted with 725, S P

Image of Uniretic 25 mg-15 mg
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What is the most important information I should know about hydrochlorothiazide and moexipril?

Multum donot

Do not use this medication if you are unable to urinate.

You should not use this medication if you are allergic to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).

Before taking hydrochlorothiazide and moexipril, tell your doctor if you have kidney disease (or are on dialysis), liver disease, glaucoma, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs or penicillin.

Multum nopreg

Moexipril can cause birth defects in the baby if you take the medication during pregnancy. Do not use hydrochlorothiazide and moexipril without telling your doctor if you are pregnant or planning a pregnancy.

Multum donot

Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and moexipril, unless your doctor has told you to.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking hydrochlorothiazide and moexipril. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

What is hydrochlorothiazide and moexipril?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Moexipril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Moexipril lowers blood pressure and also relieves symptoms of fluid retention.

The combination of hydrochlorothiazide and moexipril is used to treat hypertension (high blood pressure).

Hydrochlorothiazide and moexipril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and moexipril?

Multum donot

Do not use this medication if you are allergic to hydrochlorothiazide or moexipril, or if you are unable to urinate.

You should not use this medication if you are allergic to other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).

To make sure you can safely take hydrochlorothiazide and moexipril, tell your doctor if you have any of these other conditions:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • glaucoma;
  • congestive heart failure;
  • gout;
  • lupus;
  • diabetes; or
  • an allergy to sulfa drugs or penicillin.
Multum nopreg

FDA pregnancy category D. Do not use this medication if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Moexipril can cause birth defects. Use effective birth control while taking hydrochlorothiazide and moexipril.

Multum nobrfeed

Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and moexipril?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Multum water

Take each dose with a full glass of water.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking hydrochlorothiazide and moexipril. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Your blood pressure will need to be checked often. Visit your doctor regularly.

Your blood and urine may also be tested if you have been vomiting or are dehydrated.

Multum emt

If you need surgery or medical tests, tell the doctor ahead of time that you are taking medication that contains hydrochlorothiazide. You may need to stop using the medicine for a short time.

Keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Multum rt

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, weakness, dizziness, dry mouth, thirst, muscle pain or weakness, or feeling like you might pass out.

What should I avoid while taking hydrochlorothiazide and moexipril?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Multum dizzy

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Multum noalcohol

Drinking alcohol can increase certain side effects of hydrochlorothiazide and moexipril.

Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and moexipril, unless your doctor has told you to.

What are the possible side effects of hydrochlorothiazide and moexipril?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • eye pain, vision problems;
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • dry mouth, thirst, nausea, vomiting;
  • feeling weak, drowsy, restless, or light-headed;
  • a red, blistering, peeling skin rash;
  • jaundice (yellowing of the skin or eyes);
  • urinating less than usual or not at all;
  • swelling, weight gain, feeling short of breath; or
  • fever, chills, body aches, flu symptoms.

Less serious side effects may include:

  • cough;
  • dizziness, headache, tired feeling;
  • muscle or back pain;
  • runny nose;
  • sleep problems (insomnia);
  • diarrhea, constipation, upset stomach; or
  • mild skin rash, increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and moexipril?

Multum dizzy

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to some of the side effects of hydrochlorothiazide and moexipril. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all other medicines you use, especially:

  • other diuretics (water pills) or blood pressure medications;
  • gold injections to treat arthritis;
  • lithium (Lithobid, Eskalith);
  • a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap);
  • digoxin (Lanoxin);
  • cholestyramine (Prevalite, Questran) or colestipol (Colestid);
  • steroids (prednisone and others);
  • a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Alodox, Avidoxy, Oraxyl, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);
  • NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren), indomethacin, naproxen (Aleve, Naprosyn), piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others; or
  • insulin or oral diabetes medication.

This list is not complete and other drugs may interact with hydrochlorothiazide and moexipril. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and moexipril.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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