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aripiprazole

Pronunciation: AR i PIP ra zole

Brand: Abilify, Abilify Discmelt

Abilify 10 mg

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Abilify 15 mg

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Abilify 20 mg

round, white, imprinted with A-010 20

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Abilify 30 mg

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Abilify 5 mg

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What is the most important information I should know about aripiprazole?

Multum donot

Aripiprazole is not for use in psychotic conditions that are related to dementia. Aripiprazole may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Multum emt

Stop using aripiprazole and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

Multum dizzy

Aripiprazole may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Multum noalcohol

Avoid drinking alcohol, which can increase some of the side effects of aripiprazole.

Multum dizzy

Before you take aripiprazole, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by aripiprazole.

Multum water

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking aripiprazole.

What is aripiprazole?

Aripiprazole is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Aripiprazole is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). It is also used together with other medications to treat major depressive disorder in adults.

Aripiprazole is also used to treat irritability and symptoms of aggression, mood swings, temper tantrums, and self-injury related to autistic disorder in children who are at least 6 years old.

Aripiprazole may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking aripiprazole?

Multum donot

Aripiprazole is not for use in psychotic conditions that are related to dementia. Aripiprazole may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Multum donot

You should not take aripiprazole if you are allergic to it.

To make sure you can safely take aripiprazole, tell your doctor if you have any of these other conditions:

  • liver or kidney disease;
  • heart disease, high blood pressure, heart rhythm problems;
  • high cholesterol or triglycerides (a type of fat in the blood);
  • a history of low white blood cell (WBC) counts;
  • a history of heart attack or stroke;
  • a history of breast cancer;
  • seizures or epilepsy;
  • a personal or family history of diabetes; or
  • trouble swallowing.
Multum emt

The liquid form (oral solution) of this medication may contain up to 15 grams of sugar per dose. Before taking aripiprazole oral solution, tell your doctor if you have diabetes.

Multum emt

The orally disintegrating tablet form of this medication may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria.

Aripiprazole may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking aripiprazole.

Multum nopreg

FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking aripiprazole, do not stop taking it without your doctor's advice.

Multum nobrfeed

Aripiprazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take aripiprazole?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Multum donot

Do not take aripiprazole for longer than 6 weeks unless your doctor has told you to.

Aripiprazole can be taken with or without food.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

To take aripiprazole orally disintegrating tablets (Abilify Discmelt):

  • Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
  • Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
  • Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
  • Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Use aripiprazole regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

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Store aripiprazole tablets at room temperature away from moisture and heat.

Aripiprazole liquid should be stored in the refrigerator and can be used for up to 6 months after opening.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, agitation, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), trouble breathing, or fainting.

What should I avoid while taking aripiprazole?

Multum dizzy

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Multum noalcohol

Drinking alcohol can increase certain side effects of aripiprazole.

Multum water

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking aripiprazole.

What are the possible side effects of aripiprazole?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum emt

Stop using aripiprazole and call your doctor at once if you have a serious side effect such as:

  • fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
  • jerky muscle movements you cannot control;
  • sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance;
  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • increased thirst or urination, loss of appetite, fruity breath odor, drowsiness, dry skin, nausea, and vomiting;
  • seizure (convulsions);
  • thoughts of hurting yourself;
  • feeling like you might pass out;
  • jaundice (yellowing of your skin or eyes); or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • choking or trouble swallowing;
  • dizziness, drowsiness, or weakness;
  • constipation, mild stomach upset;
  • headache, anxiety;
  • sleep problems (insomnia); or
  • weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect aripiprazole?

Multum dizzy

Before you take aripiprazole, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by aripiprazole.

Tell your doctor about all other medicines you use, especially:

  • a medication to treat high blood pressure or a heart condition;
  • carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin);
  • rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);
  • ketoconazole (Nizoral), itraconazole (Sporanox);
  • quinidine (Quin-G); or
  • fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), or paroxetine (Paxil).

This list is not complete and other drugs may interact with aripiprazole. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about aripiprazole.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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