Many different health problems can cause the same or similar symptoms as dysfunctional uterine bleeding.

Very common and less serious conditions that can cause abnormal vaginal bleeding include:

• Uterine fibroids.
• Adenomyosis.
• An abnormally shaped uterus (uterine anomaly).

Possible serious causes of abnormal vaginal bleeding include:

• Reproductive organ cancers.
• Problems with pregnancy, such as:
  • Ectopic pregnancy.
  • Threatened or incomplete miscarriage.
  • Placenta previa or placenta abruptio.

Conditions that can cause changes in your menstrual periods include:

• Abnormal growth outside of the uterus (adnexal mass).
• Endometrial hyperplasia.
• Endometrial cancer.
• Endometriosis.
• Ovarian cysts.