Related | Appendix A Extravasation work flow algorithm non-chemotherapy
Inpatient+Ambulatory
Adult+Pediatric
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Appendix A
Management of Extravasation: Chemotherapeutic and Non-chemotherapeutic Agents
Figure 1. Workflow algorithm
Stop infusion at first suspicion of extravasation.
Disconnect the IV tubing but DO NOT remove the catheter or needle.
Gently aspirate extravasated drug.
Do NOT flush the line with normal saline or dextrose
Determine if an antidote will be given. For non-chemotherapy, work with provider to order
appropriate medication in Health Link. For chemotherapy, order antidote by delegation protocol #23.
Remove the catheter or needle unless it will be used to administer an antidote into the extravasation
site. Then remove catheter/needle after administration of the antidote, if given by this route.
Elevate the affected extremity.
Apply dry compresses to the area if indicated. Relative temperature of compress (i.e. warm or cold) is
determined by the vesicant extravasated.
Mark the extravasated site with a surgical marker and take photograph if possible.
Notify attending physician if not already done and consider need for Plastic Surgery consultation.
Document extravasation in the electronic medical record AND submit adverse event to the
Healthcare Event Reporting Online (HERO) system.
Observe patient for appropriate period (e.g. 48-72 hours).
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