Disorders related to genetic changes in the PiK3CA gene
CLOVES syndrome — A rare condition that can cause overgrowth of fatty tissue at birth or vascular malformations. It can also cause an abnormal area of skin due to the overgrowth of certain cells and problems with your spine or bones.
Klippel-Trenaunay syndrome — A disorder that commonly causes port-wine stains, overgrowth of tissues and bones and blood vessel malformations.
Megalencephaly-capillary malformation syndrome — A condition that causes a large head, port-wine stains and the overgrowth of certain body tissues.