Sean M. Ronnekleiv-Kelly, MD, FACS

  • Surgical Oncology
  • Surgery (General)

About

Dr. Ronnekleiv-Kelly is an assistant professor in the Department of Surgery, Division of Surgical Oncology at the University of Wisconsin School of Medicine and Public Health, Madison WI. He specializes in treating patients with gastrointestinal malignancies and sarcoma with a clinical focus on hepatic, biliary and pancreatic malignancy.



Dr. Ronnekleiv-Kelly’s research focuses on pancreatic and liver cancer (fibrolamellar carcinoma). Specifically, his laboratory uses complex pre-clinical mouse models of cancer in conjunction with in vitro studies to understand how an environmental sensor class of proteins (including aryl hydrocarbon receptor and circadian proteins) affects pancreas and liver cancer development and spread. Additionally, his laboratory seeks to understand how these proteins impact the various cell populations in the cancer tumor microenvironment, and how to target them for therapeutic effect.

Languages spoken
  • English
University affiliation
  • Department of Surgery

Practice locations

  • University Hospital - Surgery
    • 600 Highland Ave. / Madison, WI
    • (608) 263-7502
    • Closed now
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  • UW Carbone Cancer Center - Surgical Oncology
    • 600 Highland Ave. / Madison, WI
    • (608) 263-7502
    • Closed now
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  • University Hospital - Hepatobiliary Pancreas Clinic
    • 600 Highland Ave. / Madison, WI
    • (608) 263-7502
    • Closed now
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  • University Hospital - Pancreas Cancer Prevention Clinic
    • 600 Highland Ave. / Madison, WI
    • (608) 263-7502
    • Closed now
    • When you are at high risk of pancreatic cancer either because of a genetic predisposition or familial pancreas cancer (pancreas cancer in two or more close relatives), it’s important to have an experienced team behind you to find early warning signs before they turn into cancer. The Pancreatic Cancer Prevention team provides expertise unmatched in the United States. Combined with robust, ongoing research, the program looks for markers that could develop into pancreas cancer. Using specialized imaging techniques, our team identifies and tracks the progress of pancreas cancer precursors, including pancreatic changes in patients with high-risk hereditary conditions for pancreas cancer, and mucin producing cysts that can develop into cancer and require regular monitoring. Early identification of key changes allows for intervention before cancer develops, much like a colonoscopy identifies intestinal polyps before they turn into colon cancer.

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  • University Hospital - Pancreas Mass Clinic
    • 600 Highland Ave. / Madison, WI
    • (608) 263-7502
    • Closed now
    • Our Pancreas Mass Clinic is for people with all types of tumors in their pancreas: adenocarcinoma, neuroendocrine tumors or metastatic tumors (tumors that have spread from other parts of the body). We also see patients with tumors that are not in the pancreas, such as ampullary or duodenal cancers that require the same therapy as pancreas masses in the head of the pancreas. Our team of specialists are trained in the most advanced methods of treating these types of cancerous and non-cancerous tumors, minimizing complications and side effects.

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Education & credentials

Board certifications
  • Surgery
  • Complex General Surgical Oncology
Medical School
  • University of Colorado Denver School of Medicine, Aurora, CO
Fellowships

Complex General Surgical Oncology, The Johns Hopkins Hospital, Baltimore, MD

Residencies
  • University of Wisconsin Hospital and Clinics, Madison, WI

Specialties

Additional conditions and treatments
  • Bile Duct Resection
  • Gastrointestinal Cancer
  • Hepatopancreaticobiliary (HPB) Surgery
  • Liver Resection
  • Minimally Invasive Gastrectomy
  • Pancreatic Resection
  • Sarcoma Resection
  • Small Bowel Resection