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4D Flow MRI of the Hepatic Vasculature Before and After Portal Vein Embolization to Predict Hypertrophy of the Non-Embolized Hepatic Segments
The purpose of this study is to obtain magnetic resonance images (MRIs) using new
MR computer software. The MR scanner used in this study has been granted approval
by the Food and Drug Administration (FDA). However, the new computer software is
still considered investigational by the FDA. The software will be used to obtain the
images and to process the images after they are collected. The new software may help
us obtain more accurate images or to extract additional information from them. The
images obtained in this study will not be used for diagnosis or for treatment decisions.
Your results may help us to find out if the new software can provide diagnostic information for future patients.
This study involves three study visits, scheduled 1 day before your portal vein embolization (PVE) procedure, 1 day after the procedure, and again 30 to
40 days after the procedure. For two of the study visits (1 day before and 30 - 40 days
after), you will be asked to have some additional MR images added on to the MRI scans
done as part of your standard of care. For these two visits, the research scans will be
collected after all of your clinical scans have been completed and will add approximately
10 minutes to your clinical scan. The one study visit scheduled 1 day after your PVE
procedure, will include an MRI scan that will only be used for this research. This
research scan will take approximately 30 minutes to complete and will be scheduled
after you are discharged from the hospital.
All MRI exams require patients to be placed in the center of a large metal doughnutshaped
magnet. The MR machine produces a magnetic field that passes through your
body without disturbing any of its parts. Radio signals will be sent into your body. A
small proportion of the water in your body will send back radio signals that the machine
receives. The MR machine uses a computer to determine where these radio signals
came from to make a picture showing us what the inside of your body looks like.
- Must be between 18 - 80 years of age and scheduled for portal wein embolization (PVE)
- Patients with liver cirrhosis will be excluded
- Patients with contraindications for MR imaging will be excluded
Applicable Disease Sites
UW Hospital and Clinics