Sean M. Ronnekleiv-Kelly, MD, FACS close
Sean M. Ronnekleiv-Kelly, MD, FACS

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Sean M. Ronnekleiv-Kelly, MD, FACS Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Ronnekleiv-Kelly is an assistant professor in the Department of Surgery, Division of Surgical Oncology at the University of Wisconsin School of Medicine and Public Health, Madison WI. He specializes in treating patients with gastrointestinal malignancies and sarcoma with a clinical focus on hepatic, biliary and pancreatic malignancy.

Dr. Ronnekleiv-Kelly’s research focuses on pancreatic cancer. Specifically, to understand the interaction of various cell populations in the pancreatic cancer tumor microenvironment and to identify mechanisms for transforming the immune-permissive environment into an immune-targeting environment using pre-clinical mouse models of pancreatic cancer in conjunction with in-vitro studies to accomplish these goals.


Surgery (General)

Surgical Oncology

Bile Duct Resection

Cancer Surgeons

Gastrointestinal Cancer

Gastrointestinal Cancer (Colon and Rectal, Esophageal, Liver, Pancreatic)

Hepatopancreaticobiliary (HPB) Surgery

Liver Resection

Minimally Invasive Gastrectomy

Pancreatic Resection

Sarcoma Resection

Small Bowel Resection


UW Carbone Cancer Center
(608) 263-7502 | (800) 323-8942 | Map
University Hospital
(608) 263-7502 | (800) 323-8942 | Map
University Hospital
(608) 263-7502 | (800) 323-8942 | Map
University Hospital
(608) 263-7502 | (800) 323-8942 | Map
University Hospital
(608) 263-7502 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Surgery

Professional Certifications and Education

Board Certification Surgery

Complex General Surgical Oncology, The Johns Hopkins Hospital, Baltimore, MD

Residency University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Colorado Denver School of Medicine, Aurora, CO

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
PubMed Articles
Witt JS Kuczmarska-Haas A Lubner M Reeder SB Cho SY Minter R Weber S Ronnekleiv-Kelly S Abbott D LoConte N Mulkerin DL Lubner SJ Uboha NV Deming D Ritter MA Mohindra P Bassetti MF A Phase 1 Dose Escalation Study of Neoadjuvant SBRT Plus Elective Nodal Radiation with Concurrent Capecitabine for Resectable Pancreatic Cancer. Int J Radiat Oncol Biol Phys . 2021 Feb 1;109(2):458-463
[PubMed ID: 32942002]
Schwartz PB Stahl CC Vande Walle KA Pokrzywa CJ Cherney Stafford LM Aiken T Barrett J Acher AW Leverson G Ronnekleiv-Kelly S Weber SM Abbott DE What Drives High Costs of Cytoreductive Surgery and HIPEC: Patient, Provider or Tumor? Ann Surg Oncol . 2020 Dec;27(13):4920-4928
[PubMed ID: 32415351]
Turgeon MK Gamboa AC Lee RM Zaidi MY Kimbrough C Grotz T Fournier K Powers B Dineen S Veerapong J Clarke C Mogal H Patel SH Lambert L Ronnekleiv-Kelly S Raoof M Fackche N Greer JB Staley CA Cloyd JM Maithel SK Winer JH The Intersection of Age and Tumor Biology with Postoperative Outcomes in Patients After Cytoreductive Surgery and HIPEC. Ann Surg Oncol . 2020 Dec;27(13):4894-4907
[PubMed ID: 32378087]
Eng OS Blakely AM Lafaro KJ Fournier KF Fackche NT Johnston FM Dineen S Powers B Hendrix R Lambert LA Ronnekleiv-Kelly S Walle KV Grotz TE Leiting JL Patel SH Dhar VK Baumgartner JM Lowy AM Clarke CN Mogal H Zaidi MY Staley CA Kimbrough C Cloyd JM Lee B Raoof M Institutional variation in recovery after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: An opportunity for enhanced recovery pathways. J Surg Oncol . 2020 Oct;122(5):980-985
[PubMed ID: 32627199]
Wiseman JT Ethun CG Cloyd JM Shelby R Suarez-Kelly L Tran T Poultsides G Mogal H Clarke C Tseng J Roggin KK Chouliaras K Votanopoulos K Krasnick B Fields R Walle KV Ronnekleiv-Kelly S Howard JH Cardona K Grignol V Analysis of textbook outcomes among patients undergoing resection of retroperitoneal sarcoma: A multi-institutional analysis of the US Sarcoma Collaborative. J Surg Oncol . 2020 Jul 21;
[PubMed ID: 32696475]
Acher AW Barrett JR Schwartz PB Stahl C Aiken T Ronnekleiv-Kelly S Minter RM Leverson G Weber S Abbott DE Early vs Late Readmissions in Pancreaticoduodenectomy Patients: Recognizing Comprehensive Episodic Cost to Help Guide Bundled Payment Plans and Hospital Resource Allocation. J Gastrointest Surg . 2020 Jul 15;
[PubMed ID: 32671797]
Beal EW Ahmed A Grotz T Leiting J Fournier KF Lee AJ Dineen S Dessureault S Baumgartner JM Veerapong J Clarke C Strong E Maithel SK Zaidi MY Patel S Dhar V Hendrix R Lambert L Johnston F Fackche N Raoof M LaRocca C Ronnekleiv-Kelly S Pokrzywa C Pawlik TM Abdel-Misih S Cloyd JM Trends in the indications for and short-term outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Am J Surg . 2020 Mar;219(3):478-483
[PubMed ID: 31558307]
Zaidi MY Lee RM Gamboa AC Speegle S Cloyd JM Kimbrough C Grotz T Leiting J Fournier K Lee AJ Dineen S Dessureault S Kelly KJ Kotha NV Clarke C Gamblin TC Patel SH Lee TC Hendrix RJ Lambert L Ronnekleiv-Kelly S Pokrzywa C Blakely AM Lee B Johnston FM Fackche N Russell MC Maithel SK Staley CA 3rd Preoperative Risk Score for Predicting Incomplete Cytoreduction: A 12-Institution Study from the US HIPEC Collaborative. Ann Surg Oncol . 2020 Jan;27(1):156-164
[PubMed ID: 31602579]
Levinsky NC Morris MC Wima K Sussman JJ Ahmad SA Cloyd JM Kimbrough C Fournier K Lee A Dineen S Dessureault S Veerapong J Baumgartner JM Clarke C Zaidi MY Staley CA Maithel SK Leiting J Grotz T Lambert L Hendrix RJ Ronnekleiv-Kelly S Pokrzywa C Raoof M Eng OS Johnston FM Greer J Patel SH Should We Be Doing Cytoreductive Surgery with HIPEC for Signet Ring Cell Appendiceal Adenocarcinoma? A Study from the US HIPEC Collaborative. J Gastrointest Surg . 2020 Jan;24(1):155-164
[PubMed ID: 31428960]
Melstrom LG Eng OS Raoof M Singh G Fong Y Latorre K Choi GH Salem R Bentrem DJ Lewandowski R Makris E Poultsides G Dhar VK Chadalavada S Shah SA Johnson AC Sekhar A Kies D Maithel SK Rocha F Alseidi A Hagendoorn J Borel Rinkes IHM Fisher AV Ronnekleiv-Kelly S Weber SM Winslow ER Abbott DE Is hepatectomy safe following Yttrium-90 therapy? A multi-institutional international experience. HPB (Oxford) . 2019 Nov;21(11):1520-1526
[PubMed ID: 31005493]
Dave A Beal EW Lopez-Aguiar AG Poultsides G Makris E Rocha FG Kanji Z Ronnekleiv-Kelly S Rendell VR Fields RC Krasnick BA Idrees K Smith PM Nathan H Beems M Maithel SK Pawlik TM Schmidt CR Dillhoff ME Evaluating the ACS NSQIP Risk Calculator in Primary Pancreatic Neuroendocrine Tumor: Results from the US Neuroendocrine Tumor Study Group. J Gastrointest Surg . 2019 Nov;23(11):2225-2231
[PubMed ID: 30941685]
Lee CW Ronnekleiv-Kelly S Autoimmune Diseases of the Biliary Tract: A Review. Surg Clin North Am . 2019 Apr;99(2):185-201
[PubMed ID: 30846029]
Moris D Ronnekleiv-Kelly S Kostakis ID Tsilimigras DI Beal EW Papalampros A Dimitroulis D Felekouras E Pawlik TM Operative Results and Oncologic Outcomes of Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Versus Two-Stage Hepatectomy (TSH) in Patients with Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-Analysis. World J Surg . 2018 Mar;42(3):806-815
[PubMed ID: 28798996]
Burkhart RA Javed AA Ronnekleiv-Kelly S Wright MJ Poruk KE Eckhauser F Makary MA Cameron JL Wolfgang CL He J Weiss MJ The use of negative pressure wound therapy to prevent post-operative surgical site infections following pancreaticoduodenectomy. HPB (Oxford) . 2017 Sep;19(9):825-831
[PubMed ID: 28602643]
Moris D Ronnekleiv-Kelly S Rahnemai-Azar AA Felekouras E Dillhoff M Schmidt C Pawlik TM Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review. J Gastrointest Surg . 2017 Jun;21(6):1076-1085
[PubMed ID: 28364212]
Wilson A Winner M Yahanda A Andreatos N Ronnekleiv-Kelly S Pawlik TM Factors associated with decisional regret among patients undergoing major thoracic and abdominal operations. Surgery . 2017 Apr;161(4):1058-1066
[PubMed ID: 27993362]
Winner M Wilson A Ronnekleiv-Kelly S Smith TJ Pawlik TM A Singular Hope: How the Discussion Around Cancer Surgery Sometimes Fails. Ann Surg Oncol . 2017 Jan;24(1):31-37
[PubMed ID: 27638674]
Andreatos N Ronnekleiv-Kelly S Margonis GA Sasaki K Gani F Amini N Wilson A Pawlik TM From bench to bedside: Clinical implications of KRAS status in patients with colorectal liver metastasis. Surg Oncol . 2016 Sep;25(3):332-8
[PubMed ID: 27566041]
Riordan AM Thomas MK Ronnekleiv-Kelly S Warner T Geiger PG Kennedy GD Utility of micro-ribonucleic acid profile for predicting recurrence of rectal cancer. J Surg Res . 2012 Sep;177(1):87-92
[PubMed ID: 22480843]