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Robert A. Pearce, MD, PhD

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Robert A. Pearce, MD, PhD Print Friendly Page

Chair, Department of Anesthesiology
Faculty, University of Wisconsin School of Medicine and Public Health

Robert A. Pearce, PhD, MD, earned his medical degree from the University of Virginia in Charlottesville, where he also completed his residency.




University Hospital
(608) 263-8100 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Anesthesiology

Professional Certifications and Education

Board Certification Anesthesiology
Fellowship University of Virginia, Charlottesville, VA
Residency University of Virginia, Charlottesville, VA
Internship University of Virginia, Charlottesville, VA
Medical School University of Virginia School of Medicine, Charlottesville, VA

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
PubMed Articles
Ruhl DA Bomba-Warczak E Watson ET Bradberry MM Peterson TA Basu T Frelka A Evans CS Briguglio JS Basta T Stowell MHB Savas JN Roopra A Pearce RA Piper RC Chapman ER Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways. Nat Commun . 2019 Aug 6;10(1):3532
[PubMed ID: 31387992]
Perouansky M MacIver MB Pearce RA Wake Up, Neurons! Astrocytes Calling. Anesthesiology . 2019 Mar;130(3):361-363
[PubMed ID: 30707121]
Xue R Ruhl DA Briguglio JS Figueroa AG Pearce RA Chapman ER Doc2-mediated superpriming supports synaptic augmentation. Proc Natl Acad Sci U S A . 2018 Jun 12;115(24):E5605-E5613
[PubMed ID: 29844163]
Resto PJ Bhat A Stava E Lor C Merriam E Diaz-Rivera RE Pearce R Blick R Williams JC Flow characterization and patch clamp dose responses using jet microfluidics in a tubeless microfluidic device. J Neurosci Methods . 2017 Nov 1;291:182-189
[PubMed ID: 28842193]
Amlong CA Perkins MG Houle TT Miller KW Pearce RA Contrasting Effects of the γ-Aminobutyric Acid Type A Receptor β3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB. Anesth Analg . 2016 Nov;123(5):1241-1246
[PubMed ID: 27331778]
Parks CL Tucker W Amlong CA Mecozzi S Pearce RA Lipid-free Fluoropolymer-based Propofol Emulsions and Lipid Reversal of Propofol Anesthesia in Rats. Anesthesiology . 2016 Jun;124(6):1328-37
[PubMed ID: 26938988]
Engin E Zarnowska ED Benke D Tsvetkov E Sigal M Keist R Bolshakov VY Pearce RA Rudolph U Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. J Neurosci . 2015 Oct 7;35(40):13698-712
[PubMed ID: 26446222]
Rodgers FC Zarnowska ED Laha KT Engin E Zeller A Keist R Rudolph U Pearce RA Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells. J Neurosci . 2015 Jul 1;35(26):9707-16
[PubMed ID: 26134653]
Balakrishnan S Pearce RA Spatiotemporal characteristics and pharmacological modulation of multiple gamma oscillations in the CA1 region of the hippocampus. Front Neural Circuits . 2014;8:150
[PubMed ID: 25628540]
Burkat PM Lor C Perouansky M Pearce RA Enhancement of α5-containing γ-aminobutyric acid type A receptors by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6) is abolished by the β3(N265M) mutation. Anesth Analg . 2014 Dec;119(6):1277-84
[PubMed ID: 25211390]
Balakrishnan S Pearce RA Midazolam and atropine alter theta oscillations in the hippocampal CA1 region by modulating both the somatic and distal dendritic dipoles. Hippocampus . 2014 Oct;24(10):1212-31
[PubMed ID: 24862458]
Gemperline E Laha K Scarlett CO Pearce RA Li L Measurement of NMDA Receptor Antagonist, CPP, in Mouse Plasma and Brain Tissue Following Systematic Administration Using Ion-Pair LCMS/MS. Anal Methods . 2014 Aug 21;6(16):6389-6396
[PubMed ID: 25663848]
Goldschen-Ohm MP Haroldson A Jones MV Pearce RA A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors. J Gen Physiol . 2014 Jul;144(1):27-39
[PubMed ID: 24981228]
Dai S Perouansky M Pearce RA Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations. Anesthesiology . 2012 Apr;116(4):816-23
[PubMed ID: 22343472]
Jee JP Parlato MC Perkins MG Mecozzi S Pearce RA Exceptionally stable fluorous emulsions for the intravenous delivery of volatile general anesthetics. Anesthesiology . 2012 Mar;116(3):580-5
[PubMed ID: 22354241]
Johnson RA Simmons KT Fast JP Schroeder CA Pearce RA Albrecht RM Mecozzi S Histamine release associated with intravenous delivery of a fluorocarbon-based sevoflurane emulsion in canines. J Pharm Sci . 2011 Jul;100(7):2685-92
[PubMed ID: 21246564]
Perouansky M Pearce RA How we recall (or don't): the hippocampal memory machine and anesthetic amnesia. Can J Anaesth . 2011 Feb;58(2):157-66
[PubMed ID: 21170624]
Perouansky M Rau V Ford T Oh SI Perkins M Eger EI 2nd Pearce RA Slowing of the hippocampal θ rhythm correlates with anesthetic-induced amnesia. Anesthesiology . 2010 Dec;113(6):1299-309
[PubMed ID: 21042201]
Blake AJ Rodgers FC Bassuener A Hippensteel JA Pearce TM Pearce TR Zarnowska ED Pearce RA Williams JC A microfluidic brain slice perfusion chamber for multisite recording using penetrating electrodes. J Neurosci Methods . 2010 May 30;189(1):5-13
[PubMed ID: 20219536]
Ferrarelli F Massimini M Sarasso S Casali A Riedner BA Angelini G Tononi G Pearce RA Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc Natl Acad Sci U S A . 2010 Feb 9;107(6):2681-6
[PubMed ID: 20133802]