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Ozioma C. Okonkwo, PhD

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Ozioma C. Okonkwo, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Ozioma C. Okonkwo, PhD, is an Assistant Professor of Medicine at the University of Wisconsin School of Medicine and Public Health. He specializes in the neuropsychological evaluation of geriatric cognitive disorders, especially those due to suspected Alzheimer's disease.



University Station Clinic
(608) 263-7740 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Licenses Licensed Clinical Psychologist

NIH T32 AG027668, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD

VA Advanced Fellowship in Geriatrics, the Geriatric Research, Education, and Clinical Center (GRECC), William S. Middleton Memorial Veterans Hospital, Madison, WI

Internship Warren Alpert Medical School of Brown University, Providence, RI
Medical School University of Alabama, Birmingham, AL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Okonkwo's research focuses on clarifying how alterations in the brain and other biomolecules (such as cerebrospinal fluid β-amyloid) place some cognitively-normal individuals on a pernicious trajectory that culminates in probable Alzheimer's disease. In this context, Dr. Okonkwo is also interested in discovering new knowledge concerning the modulation of the link between brain changes and cognitive decline by both modifiable (e.g., cognitively stimulating activities, physical exercise) and non-modifiable (e.g., genetic vulnerability) factors.

PubMed Articles
Pozorski V Oh JM Adluru N Merluzzi AP Theisen F Okonkwo O Barzgari A Krislov S Sojkova J Bendlin BB Johnson SC Alexander AL Gallagher CL Longitudinal white matter microstructural change in Parkinson's disease. Hum Brain Mapp . 2018 Oct;39(10):4150-4161
[PubMed ID: 29952102]
Stern Y Arenaza-Urquijo EM Bartrés-Faz D Belleville S Cantilon M Chetelat G Ewers M Franzmeier N Kempermann G Kremen WS Okonkwo O Scarmeas N Soldan A Udeh-Momoh C Valenzuela M Vemuri P Vuoksimaa E Reserve, Resilience and Protective Factors PIA Empirical Definitions and Conceptual Frameworks Workgroup. Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance. Alzheimers Dement . 2018 Sep 14;
[PubMed ID: 30222945]
Eleje GU Eke AC Ezebialu IU Ikechebelu JI Ugwu EO Okonkwo OO Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations. Cochrane Database Syst Rev . 2018 Aug 24;8:CD012464
[PubMed ID: 30141832]
McAlvin JB Wylie RG Ramchander K Nguyen MT Lok CK Moroi M Shomorony A Vasilyev NV Armstrong P Yang J Lieber AM Okonkwo OS Karnik R Kohane DS Antibody-modified conduits for highly selective cytokine elimination from blood. JCI Insight . 2018 Jul 12;3(13)
[PubMed ID: 29997301]
Yang R Okonkwo OS Zurakowski D Kohane DS Synergy between chemical permeation enhancers and drug permeation across the tympanic membrane. J Control Release . 2018 Jun 19;
[PubMed ID: 29932959]
Hao L Wang J Page D Asthana S Zetterberg H Carlsson C Okonkwo OC Li L Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease. Sci Rep . 2018 Jun 18;8(1):9291
[PubMed ID: 29915347]
Barzgari A Sojkova J Maritza Dowling N Pozorski V Okonkwo OC Starks EJ Oh J Thiesen F Wey A Nicholas CR Johnson S Gallagher CL Arterial spin labeling reveals relationships between resting cerebral perfusion and motor learning in Parkinson's disease. Brain Imaging Behav . 2018 May 9;
[PubMed ID: 29744796]
Law LL Rol RN Schultz SA Dougherty RJ Edwards DF Koscik RL Gallagher CL Carlsson CM Bendlin BB Zetterberg H Blennow K Asthana S Sager MA Hermann BP Johnson SC Cook DB Okonkwo OC Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer's disease. Alzheimers Dement (Amst) . 2018;10:188-195
[PubMed ID: 29527551]
Swamy L Beare NAV Okonkwo O Mahmoud TH Funduscopy in Cerebral Malaria Diagnosis: An International Survey of Practice Patterns. Am J Trop Med Hyg . 2018 Feb;98(2):516-519
[PubMed ID: 29280430]
Zuelsdorff ML Koscik RL Okonkwo OC Peppard PE Hermann BP Sager MA Johnson SC Engelman CD Reliability of a Novel Social Activity Questionnaire: Perceived Social Support and Verbal Interaction in the Wisconsin Registry for Alzheimer's Prevention. J Aging Health . 2018 Feb;30(2):305-320
[PubMed ID: 28553788]
Dougherty RJ Lindheimer JB Stegner AJ Van Riper S Okonkwo OC Cook DB An Objective Method to Accurately Measure Cardiorespiratory Fitness in Older Adults Who Cannot Satisfy Widely Used Oxygen Consumption Criteria. J Alzheimers Dis . 2018;61(2):601-611
[PubMed ID: 29226867]
Zuelsdorff ML Koscik RL Okonkwo OC Peppard PE Hermann BP Sager MA Johnson SC Engelman CD Social support and verbal interaction are differentially associated with cognitive function in midlife and older age. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn . 2017 Dec 15;:1-17
[PubMed ID: 29241403]
Johnson SC Koscik RL Jonaitis EM Clark LR Mueller KD Berman SE Bendlin BB Engelman CD Okonkwo OC Hogan KJ Asthana S Carlsson CM Hermann BP Sager MA The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions. Alzheimers Dement (Amst) . 2018;10:130-142
[PubMed ID: 29322089]
Okonkwo ON Hassan AO Gyasi ME Oderinlo O Bilateral simultaneous macular infarction with spontaneous visual recovery in genotype ss hemoglobinopathy patient. Niger J Clin Pract . 2017 Dec;20(12):1651-1655
[PubMed ID: 29379002]
Curtin KB Watson AE Wang J Okonkwo OC Lyon ME Pediatric advance care planning (pACP) for teens with cancer and their families: Design of a dyadic, longitudinal RCCT. Contemp Clin Trials . 2017 Nov;62:121-129
[PubMed ID: 28844985]
Theisen F Leda R Pozorski V Oh JM Adluru N Wong R Okonkwo O Dean DC 3rd Bendlin BB Johnson SC Alexander AL Gallagher CL Evaluation of striatonigral connectivity using probabilistic tractography in Parkinson's disease. Neuroimage Clin . 2017;16:557-563
[PubMed ID: 28971007]
Golnik KC Law JC Ramasamy K Mahmoud TH Okonkwo ON Singh J Arevalo JF The Ophthalmology Surgical Competency Assessment Rubric for Vitrectomy. Retina . 2017 Sep;37(9):1797-1804
[PubMed ID: 28613227]
Sprecher KE Koscik RL Carlsson CM Zetterberg H Blennow K Okonkwo OC Sager MA Asthana S Johnson SC Benca RM Bendlin BB Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults. Neurology . 2017 Aug 1;89(5):445-453
[PubMed ID: 28679595]
Lassen-Greene CL Steward K Okonkwo O Porter E Crowe M Vance DE Griffith HR Ball K Marson DC Wadley VG Mild Cognitive Impairment and Changes in Everyday Function Over Time: The Importance of Evaluating Both Speed and Accuracy. J Geriatr Psychiatry Neurol . 2017 Jul;30(4):220-227
[PubMed ID: 28639877]
Boots EA Schultz SA Clark LR Racine AM Darst BF Koscik RL Carlsson CM Gallagher CL Hogan KJ Bendlin BB Asthana S Sager MA Hermann BP Christian BT Dubal DB Engelman CD Johnson SC Okonkwo OC <i>BDNF</i> Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention. Neurology . 2017 May 30;88(22):2098-2106
[PubMed ID: 28468845]