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Nasia Safdar, MD

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Nasia Safdar, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Nasia Safdar has been the Medical Director of Infection Control at UW Hospital and Clinics since 2009. She came to Wisconsin in 1997 for her residency and fellowship. She is board certified in infectious disease and she focuses on healthcare-associated infections, particularly in the acute care setting. Dr. Safdar believes that many health care-associated infections can be prevented with adherence to known best practices. As medical director for the department of infection prevention, her job is to lead the department in its mission of reducing healthcare-associated infections by identifying, testing and implementing interventions that have benefit for reducing health care associated infections (HAI).


She is an associate professor of infectious diseases at the University of Wisconsin School of Medicine and Public Health and the Associate Chief of Staff for Research at the William S. Middleton VA Hospital. Her research includes the evaluation of novel and innovative strategies for prevention of HAI. She is currently leading the fecal bacteriotherapy program at UW Hospital and is the principal investigator of a current ongoing VA-funded trial of probiotics for reducing HAI.


Infectious Diseases


University Hospital
(608) 263-0946 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Infectious Diseases
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship Sir Ganga Ram Hospital, Lahore, Pakistan
Medical School Aga Khan University Medical College, Karachi, Pakistan

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Safdar is interested in examining the efficacy of novel interventions to reduce healthcare-associated infection such as the use of probiotics for reducing colonization by methicillin-resistant Staphylococcus aureus and Clostridium difficileand has ongoing trials in this area. 

PubMed Articles
Eggers S Gennings C Malecki KMC Safdar N Arora M Exposure to environmental chemical mixtures is associated with nasal colonization by Staphylococcus aureus: NHANES 2001-2004. Environ Res . 2020 Nov;190:109994
[PubMed ID: 32771801]
Scaria E Powell WR Birstler J Alagoz O Shirley D Kind AJH Safdar N Neighborhood disadvantage and 30-day readmission risk following Clostridioides difficile infection hospitalization. BMC Infect Dis . 2020 Oct 16;20(1):762
[PubMed ID: 33066737]
Keating JA McKinley L Safdar N COVID-19 and Antibiotic Stewardship: Using a Systems Engineering Approach to Maintain Patient Safety. Infect Control Hosp Epidemiol . 2020 Oct 12;:1-10
[PubMed ID: 33040756]
Lepak AJ Shirley DK Buys A Stevens L Safdar N Implementation of Infection Control Measures to Prevent Healthcare-associated Transmission of SARS-CoV-2. Infect Control Hosp Epidemiol . 2020 Oct 12;:1-13
[PubMed ID: 33040753]
Ramanathan S Suda KJ Fitzpatrick MA Guihan M Goedken CC Safdar N Evans M Jones M Pfeiffer CD Perencevich EN Rubin M Evans CT QUERI CARRIAGE Program. A survey of infection control strategies for carbapenem-resistant <i>Enterobacteriaceae</i> in Department of Veterans' Affairs facilities. Infect Control Hosp Epidemiol . 2020 Sep 22;:1-4
[PubMed ID: 32959749]
Lepak AJ Chen DJ Buys A Stevens L Safdar N Utility of Repeat Nasopharyngeal SARS-CoV-2 RT-PCR Testing and Refinement of Diagnostic Stewardship Strategies at a Tertiary Care Academic Center in a Low-Prevalence Area of the United States. Open Forum Infect Dis . 2020 Sep;7(9):ofaa388
[PubMed ID: 32964068]
Tischendorf J Brunner M Knobloch MJ Schulz L Barker A Wright MO Lepak A Safdar N Evaluation of a successful fluoroquinolone restriction intervention among high-risk patients: A mixed-methods study. PLoS One . 2020;15(8):e0237987
[PubMed ID: 32841259]
Rivera F Safdar N Ledeboer N Schaack G Chen DJ Munoz-Price LS Prevalence of SARS-CoV-2 asymptomatic infections in two large academic health systems in Wisconsin. Clin Infect Dis . 2020 Aug 19;
[PubMed ID: 32812030]
Barker AK Scaria E Safdar N Alagoz O Evaluation of the Cost-effectiveness of Infection Control Strategies to Reduce Hospital-Onset Clostridioides difficile Infection. JAMA Netw Open . 2020 Aug 3;3(8):e2012522
[PubMed ID: 32789514]
Pop-Vicas A Stern R Osman F Safdar N Variability in infection surveillance methods and impact on surgical site infection rates. Am J Infect Control . 2020 Jul 2;
[PubMed ID: 32622837]
Weiner S Schwartz A Altman L Ball S Bartle B Binns-Calvey A Chan C Falck-Ytter C Frenchman M Gee B Jackson JL Jordan N Kass B Kelly B Safdar N Scholcoff C Sharma G Weaver F Wopat M Evaluation of a Patient-Collected Audio Audit and Feedback Quality Improvement Program on Clinician Attention to Patient Life Context and Health Care Costs in the Veterans Affairs Health Care System. JAMA Netw Open . 2020 Jul 1;3(7):e209644
[PubMed ID: 32735338]
Malecki K Keating JA Safdar N Crisis Communication and Public Perception of COVID-19 Risk in the Era of Social Media. Clin Infect Dis . 2020 Jun 16;
[PubMed ID: 32544242]
Abad CL Barker AK Safdar N A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associated <i>C. difficile</i> and multidrug-resistant organisms. Infect Control Hosp Epidemiol . 2020 Jun;41(6):691-709
[PubMed ID: 32216852]
Kates AE Gaulke I De Wolfe T Zimbric M Haight K Watson L Suen G Kim K Safdar N Fecal microbiota transplantation for patients on antibiotic treatment with <i>C. difficile</i> infection history (GRAFT): Study protocol for a phase II, randomized, double-blind, placebo-controlled trial to prevent recurrent <i>C. difficile</i> infections. Contemp Clin Trials Commun . 2020 Jun;18:100576
[PubMed ID: 32518854]
Pop-Vicas AE Abad C Baubie K Osman F Heise C Safdar N Colorectal bundles for surgical site infection prevention: A systematic review and meta-analysis. Infect Control Hosp Epidemiol . 2020 May 11;:1-8
[PubMed ID: 32389140]
Barker AK Scaria E Alagoz O Sethi AK Safdar N Reducing <i>C. difficile</i> in children: An agent-based modeling approach to evaluate intervention effectiveness. Infect Control Hosp Epidemiol . 2020 May;41(5):522-530
[PubMed ID: 32052722]
Musuuza JS Roberts TJ Hundt AS Carayon P Zimbric ML Schuetz V Reppen M Smith W Koffarnus K Brown RL Bowling J Jalali K Safdar N Implementing daily chlorhexidine gluconate treatment for the prevention of healthcare-associated infections in non-intensive care settings: A multiple case analysis. PLoS One . 2020;15(4):e0232062
[PubMed ID: 32330165]
Jasper AS Musuuza JS Tischendorf JS Stevens VW Gamage SD Osman F Safdar N Are Fluoroquinolones or Macrolides Better for Treating Legionella Pneumonia? A Systematic Review and Meta-analysis. Clin Infect Dis . 2020 Apr 16;
[PubMed ID: 32296816]
Ai A Anderson L Safdar N Shirley D Barriers and facilitators to standardization of ultrasound use and probe disinfection in the ambulatory setting. Infect Control Hosp Epidemiol . 2020 Apr;41(4):469-471
[PubMed ID: 32036803]
Butt AA Yan P Aslam S Sherman KE Siraj D Safdar N Hameed B Hepatitis C virologic response in hepatitis B and C coinfected persons treated with directly acting antiviral agents: Results from ERCHIVES. Int J Infect Dis . 2020 Mar;92:184-188
[PubMed ID: 31978574]