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Matthew W. Squire, MD, MS

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Matthew W. Squire, MD, MS Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Squire specializes in surgical care of the hip and knee. After his orthopedic surgical training, he completed a year of specialty fellowship training which focused on joint preservation surgery, routine and complex hip replacement, as well as routine and complex knee replacement. He is certified by the American Board of Orthopaedic Surgery (ABOS). He is a member of the American Association of Hip and Knee Surgeons. He is a member of the Arthritis Foundation. He is Co-Director of the Arthritis and Joint Replacement Program at the UW School of Medicine and Public Health.


Dr. Squire's surgical practice is split between hip and knee disorders. Dr. Squire routinely performs surgical care for young active patients (16 and older) as well as older patients. Dr. Squire's hip practice includes surgical care of hip labral injuries, femoral acetabular impingement, sports-related hip injuries, non-arthritic adolescent and adult hip pain, hip arthritis and failed hip replacements. The most common hip surgeries he performs are hip arthroscopy, open surgical hip dislocation, minimally-invasive and anterior hip replacement and revision (re-do) hip replacement surgery. Dr. Squire's knee practice includes surgical care of adult knee pain, knee arthritis and failed knee replacements. The most common knee surgeries he performs are knee replacement, partial knee replacement and revision (re-do) knee replacement surgery.


Dr. Squire attended the University of Iowa for his undergraduate degree (B.S.) in Exercise Science. He obtained his Biomedical Engineering Masters of Science degree from Rensselaer Polytechnic Institute in New York. He received his M.D. from the University of Iowa, where he was inducted into the medical school honor society. His orthopedic surgical training was completed at the University of Wisconsin Hospitals and Clinics. He then traveled to Charlotte, N.C., where he performed a year of specialty fellowship surgical training that focused on joint preservation surgery, complex and routine hip replacement surgery, as well as complex and routine knee replacement surgery (OrthoCarolina - Adult Reconstruction Fellowship).


In addition to hip and knee surgery, Dr. Squire is actively involved in orthopedic research and hip and knee replacement implant design, as well as education of medical students and orthopedic surgical trainees. Dr. Squire's research efforts on prevention and treatment of orthopedic infections, performance of hip and knee replacement implants and stem cells and cartilage restoration have been published and presented in many national and international journals and conferences. Dr. Squire served as the UW Hospitals and Clinics Orthopedic Program Director for seven years, during which time he was responsible for the selection of orthopedic surgery trainees (residents) as well as the design and oversight of their educational curriculum. Dr. Squire continues to be actively involved in hip and knee replacement implant design, holds multiple patents and is co-designer of an internationally distributed hip implant system.


Orthopedic Surgery

Hip Arthroscopy

Hip Replacement or Resurfacing Revision

Knee Pain

Knee Replacement Revision

Orthopedic Joint Reconstruction and Replacement

Robotic Partial Knee Replacement

Total Hip Replacement (Arthroplasty)

Total Knee Replacement (Arthroplasty)


UW Health at The American Center
(608) 263-7540 | (844) 607-4800 | Map

UW School of Medicine and Public Health

Department of Orthopedics and Rehabilitation

Professional Certifications and Education

Board Certification Orthopedic Surgery
Fellowship Charlotte Orthopedic Specialists, Charlotte, NC
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Iowa Carver College of Medicine, Iowa City, IA

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Squire’s research interests include prevention and treatment of orthopedic infection, hip resurfacing, robotic hip and knee surgery, design of hip and knee replacement devices, avascular necrosis, cartilage regeneration and non-destructive implant removal.