L. Lee Eckhardt, MD close
L. Lee Eckhardt, MD

New Patients

Contact the Welcome Center for help choosing a new primary care doctor.

For Referring Physicians

How to refer a patient

L. Lee Eckhardt, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Lee Eckhardt, MD, MS, is a clinical and research electrophysiologist and treats a wide variety of arrhythmia conditions particularly conditions that cause ventricular arrhythmia or sudden death. She is an expert in inherited arrhythmia conditions and directs both clinical and basic science arrhythmia research projects related to these interests with an overarching goal of prevention of sudden cardiac death (SCD).  She also co-directs the Inherited Arrhythmia Clinic and the Cardiac Arrest Prevention ProgramFor more information about her research program, click here.



Research Park Clinic
(608) 263-1530 | (800) 323-8942 | Map
Research Park Clinic
(608) 263-1530 | (800) 323-8942 | Map
University Hospital
(608) 263-1530 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Clinical Cardiac Electrophysiology
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Brigham and Women's Hospital, Boston, MA
Residency Georgetown University Medical Center, Washington, DC
Medical School George Washington University School of Medicine and Health Sciences, Washington, D.C.

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Eckhardt’s research interests are related to the cellular mechanisms of inherited arrhythmia syndromes and cellular electrophysiology.

PubMed Articles
Alexanian RA Mahapatra K Lang D Vaidyanathan R Markandeya YS Gill RK Zhai AJ Dhillon A Lea MR Abozeid S Schmuck EG Raval AN Eckhardt LL Glukhov AV Lalit PA Kamp TJ Induced cardiac progenitor cells repopulate decellularized mouse heart scaffolds and differentiate to generate cardiac tissue. Biochim Biophys Acta Mol Cell Res . 2020 Mar;1867(3):118559
[PubMed ID: 31634503]
Reilly L Narichania AD Eckhardt LL Shocking Aspects of Nonconductive Plastics: Electrophysiologic Implications of Plasticizers. Circ Arrhythm Electrophysiol . 2019 Jul;12(7):e007522
[PubMed ID: 31248278]
Eckhardt LL Kalscheur MM Replacing Hardware With "Viralware". J Am Coll Cardiol . 2019 Apr 9;73(13):1688-1690
[PubMed ID: 30947922]
Vaidyanathan R Reilly L Eckhardt LL Caveolin-3 Microdomain: Arrhythmia Implications for Potassium Inward Rectifier and Cardiac Sodium Channel. Front Physiol . 2018;9:1548
[PubMed ID: 30473666]
Frasier CR Zhang H Offord J Dang LT Auerbach DS Shi H Chen C Goldman AM Eckhardt LL Bezzerides VJ Parent JM Isom LL Channelopathy as a SUDEP Biomarker in Dravet Syndrome Patient-Derived Cardiac Myocytes. Stem Cell Reports . 2018 Sep 11;11(3):626-634
[PubMed ID: 30146492]
Kipp RT Boynton JR Field ME Wang JF Bares A Leal MA VON Bergen NH Eckhardt LL Outcomes During Intended Fluoroscopy-free Ablation in Adults and Children. J Innov Card Rhythm Manag . 2018 Sep;9:3305-3311
[PubMed ID: 30568847]
Barnett A Eckhardt L Leal MA Seal plug damage causing inappropriate detection and therapy in a subcutaneous defibrillator system. HeartRhythm Case Rep . 2019 Feb;5(2):66-69
[PubMed ID: 30820398]
Field ME Donateo P Bottoni N Iori M Brignole M Kipp RT Kopp DE Leal MA Eckhardt LL Wright JM Walsh KE Page RL Hamdan MH P-Wave Amplitude and PR Changes in Patients With Inappropriate Sinus Tachycardia: Findings Supportive of a Central Mechanism. J Am Heart Assoc . 2018 Apr 19;7(9)
[PubMed ID: 29674334]
Vaidyanathan R Van Ert H Haq KT Morotti S Esch S McCune EC Grandi E Eckhardt LL Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje Cell-Dependent Ventricular Arrhythmias. Circ Arrhythm Electrophysiol . 2018 Jan;11(1):e005800
[PubMed ID: 29326130]
Kalscheur MM Kipp RT Tattersall MC Mei C Buhr KA DeMets DL Field ME Eckhardt LL Page CD Machine Learning Algorithm Predicts Cardiac Resynchronization Therapy Outcomes: Lessons From the COMPANION Trial. Circ Arrhythm Electrophysiol . 2018 Jan;11(1):e005499
[PubMed ID: 29326129]
Kipp R Young N Barnett A Kopp D Leal MA Eckhardt LL Teelin T Hoffmayer KS Wright J Field M Injectable loop recorder implantation in an ambulatory setting by advanced practice providers: Analysis of outcomes. Pacing Clin Electrophysiol . 2017 Sep;40(9):982-985
[PubMed ID: 28691385]
Eckhardt LL Makielski JC Complexity of AF genetic susceptibility begets complexity of interpretation. Heart Rhythm . 2017 Feb;14(2):292-293
[PubMed ID: 27825974]
Van Ert HA McCune EC Orland KM Maginot KR Von Bergen NH January CT Eckhardt LL Flecainide treats a novel <i>KCNJ2</i> mutation associated with Andersen-Tawil syndrome. HeartRhythm Case Rep . 2017 Feb;3(2):151-154
[PubMed ID: 28491792]
Vaidyanathan R Markandeya YS Kamp TJ Makielski JC January CT Eckhardt LL IK1-enhanced human-induced pluripotent stem cell-derived cardiomyocytes: an improved cardiomyocyte model to investigate inherited arrhythmia syndromes. Am J Physiol Heart Circ Physiol . 2016 Jun 1;310(11):H1611-21
[PubMed ID: 27059077]
Eckhardt LL Monomorphic ventricular tachycardia in Brugada syndrome: True-true but related? Heart Rhythm . 2016 Mar;13(3):683-5
[PubMed ID: 26632641]
Van Wagoner DR Piccini JP Albert CM Anderson ME Benjamin EJ Brundel B Califf RM Calkins H Chen PS Chiamvimonvat N Darbar D Eckhardt LL Ellinor PT Exner DV Fogel RI Gillis AM Healey J Hohnloser SH Kamel H Lathrop DA Lip GY Mehra R Narayan SM Olgin J Packer D Peters NS Roden DM Ross HM Sheldon R Wehrens XH Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013. Heart Rhythm . 2015 Jan;12(1):e5-e29
[PubMed ID: 25460864]
Jones DK Liu F Vaidyanathan R Eckhardt LL Trudeau MC Robertson GA hERG 1b is critical for human cardiac repolarization. Proc Natl Acad Sci U S A . 2014 Dec 16;111(50):18073-7
[PubMed ID: 25453103]
Kalscheur MM Vaidyanathan R Orland KM Abozeid S Fabry N Maginot KR January CT Makielski JC Eckhardt LL KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia. Heart Rhythm . 2014 May;11(5):885-94
[PubMed ID: 24561538]
Vaidyanathan R Vega AL Song C Zhou Q Tan BH Berger S Makielski JC Eckhardt LL The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1: physiology and pathology related to long qt syndrome 9 (LQT9). J Biol Chem . 2013 Jun 14;288(24):17472-80
[PubMed ID: 23640888]
Eckhardt LL Leal M Hollis Z Tanega J Alberte C Cryoablation for AVNRT: importance of ablation endpoint criteria. J Cardiovasc Electrophysiol . 2012 Jul;23(7):729-34
[PubMed ID: 22509957]