Skip to main content Skip to footer
American Family Children's Hospital
SHARE TEXT
 
Douglas G. McNeel, MD, PhD close
Douglas G. McNeel, MD, PhD

New Patients

Need help selecting a primary care doctor? Contact the Welcome Center for personal assistance.

For Referring Physicians

How to refer a patient

Douglas G. McNeel, MD, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. McNeel is a genitourinary medical oncologist with a clinical and research focus on prostate cancer immunology. Since 1997 he and his laboratory have studied vaccines for prostate cancer, specifically identifying antigens to target in vaccines, testing the ability of vaccines to eliminate prostate cancer cells and translating these studies to human clinical trials.

Specialties

Medical Oncology

Bladder Cancer

Genitourinary Cancer (Bladder, Kidney, Prostate, Testicular)

Kidney Cancer

Prostate Cancer

Testicular Cancer

Clinics

UW Carbone Cancer Center
(608) 265-1700 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Medical Oncology
Fellowship Fred Hutchinson Cancer Research Center, Seattle, WA
University of Washington Medical Center, Seattle, WA
Residency University of Washington Medical Center, Seattle, WA
Internship University of Washington School of Medicine, Seattle, WA
Medical School University of Chicago, Pritzker School of Medicine, Chicago, IL

Languages Spoken

French
Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
PubMed Articles
Miller JS Morishima C McNeel DG Patel MR Kohrt HEK Thompson JA Sondel PM Wakelee HA Disis ML Kaiser JC Cheever MA Streicher H Creekmore SP Waldmann TA Conlon KC A First-in-Human Phase I Study of Subcutaneous Outpatient Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors. Clin Cancer Res . 2018 Apr 1;24(7):1525-1535
[PubMed ID: 29203590]
Wargowski E Johnson LE Eickhoff JC Delmastro L Staab MJ Liu G McNeel DG Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine. J Immunother Cancer . 2018 Mar 13;6(1):21
[PubMed ID: 29534736]
McNeel DG Therapeutic Cancer Vaccines: How Much Closer Are We? BioDrugs . 2018 Feb;32(1):1-7
[PubMed ID: 29285731]
England CG Jiang D Ehlerding EB Rekoske BT Ellison PA Hernandez R Barnhart TE McNeel DG Huang P Cai W <sup>89</sup>Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer. Eur J Nucl Med Mol Imaging . 2018 Jan;45(1):110-120
[PubMed ID: 28821924]
Kelly M McNeel D Fisch P Malkovsky M Immunological considerations underlying heat shock protein-mediated cancer vaccine strategies. Immunol Lett . 2018 Jan;193:1-10
[PubMed ID: 29129721]
Olson BM Gamat M Seliski J Sawicki T Jeffery J Ellis L Drake CG Weichert J McNeel DG Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells. Cancer Immunol Res . 2017 Dec;5(12):1074-1085
[PubMed ID: 29051161]
Zahm CD Colluru VT McNeel DG Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8<sup>+</sup> T Cells. Cancer Immunol Res . 2017 Aug;5(8):630-641
[PubMed ID: 28634215]
Johnson LE Olson BM McNeel DG Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination. J Immunother Cancer . 2017 Jul 18;5(1):56
[PubMed ID: 28716080]
Zahm CD Colluru VT McNeel DG DNA vaccines for prostate cancer. Pharmacol Ther . 2017 Jun;174:27-42
[PubMed ID: 28185916]
Ehlerding EB England CG Majewski RL Valdovinos HF Jiang D Liu G McNeel DG Nickles RJ Cai W ImmunoPET Imaging of CTLA-4 Expression in Mouse Models of Non-small Cell Lung Cancer. Mol Pharm . 2017 May 1;14(5):1782-1789
[PubMed ID: 28388076]
Olson BM Bradley ES Sawicki T Zhong W Ranheim EA Bloom JE Colluru VT Johnson LE Rekoske BT Eickhoff JC McNeel DG Safety and Immunological Efficacy of a DNA Vaccine Encoding the Androgen Receptor Ligand-Binding Domain (AR-LBD). Prostate . 2017 May;77(7):812-821
[PubMed ID: 28181678]
England CG Ehlerding EB Hernandez R Rekoske BT Graves SA Sun H Liu G McNeel DG Barnhart TE Cai W Preclinical Pharmacokinetics and Biodistribution Studies of 89Zr-Labeled Pembrolizumab. J Nucl Med . 2017 Jan;58(1):162-168
[PubMed ID: 27493273]
McNeel DG Bander NH Beer TM Drake CG Fong L Harrelson S Kantoff PW Madan RA Oh WK Peace DJ Petrylak DP Porterfield H Sartor O Shore ND Slovin SF Stein MN Vieweg J Gulley JL The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma. J Immunother Cancer . 2016;4:92
[PubMed ID: 28031820]
Heninger E Krueger TE Thiede SM Sperger JM Byers BL Kircher MR Kosoff D Yang B Jarrard DF McNeel DG Lang JM Inducible expression of cancer-testis antigens in human prostate cancer. Oncotarget . 2016 Dec 20;7(51):84359-84374
[PubMed ID: 27769045]
Rekoske BT McNeel DG Immunotherapy for prostate cancer: False promises or true hope? Cancer . 2016 Dec 1;122(23):3598-3607
[PubMed ID: 27649312]
Choueiri TK Fishman MN Escudier B McDermott DF Drake CG Kluger H Stadler WM Perez-Gracia JL McNeel DG Curti B Harrison MR Plimack ER Appleman L Fong L Albiges L Cohen L Young TC Chasalow SD Ross-Macdonald P Srivastava S Jure-Kunkel M Kurland JF Simon JS Sznol M Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma. Clin Cancer Res . 2016 Nov 15;22(22):5461-5471
[PubMed ID: 27169994]
McNeel DG TCR diversity - a universal cancer immunotherapy biomarker? J Immunother Cancer . 2016;4:69
[PubMed ID: 27879971]
Colluru VT McNeel DG B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines. Oncotarget . 2016 Oct 18;7(42):67901-67918
[PubMed ID: 27661128]
Ehlerding EB England CG McNeel DG Cai W Molecular Imaging of Immunotherapy Targets in Cancer. J Nucl Med . 2016 Oct;57(10):1487-1492
[PubMed ID: 27469363]
Colluru VT Zahm CD McNeel DG Mini-intronic plasmid vaccination elicits tolerant LAG3<sup>+</sup> CD8<sup>+</sup> T cells and inferior antitumor responses. Oncoimmunology . 2016;5(10):e1223002
[PubMed ID: 27853647]