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David R. Andes, MD close
David R. Andes, MD

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David R. Andes, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Andes’ clinical interests include general infectious diseases, transplant infectious diseases, mycology, antimicrobial pharmacokinetics and pharmacodynamics. 


Infectious Diseases

Travel Medicine


University Hospital
(608) 263-0946 | (800) 323-8942 | Map
University Hospital
(608) 890-6167 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
UnityPoint Health - Meriter
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Infectious Diseases
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Missouri School of Medicine, Columbia, MO

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

The overriding themes of our research programs are to advance our understanding of antibacterial and antifungal activity and drug resistance, and to identify new antimicrobial drug treatment strategies and drug targets.

PubMed Articles
Owens RC Jr Bulik CC Andes DR Pharmacokinetics-pharmacodynamics, computer decision support technologies, and antimicrobial stewardship: the compass and rudder. Diagn Microbiol Infect Dis . 2018 Aug;91(4):371-382
[PubMed ID: 29776710]
Zhao M Lepak AJ Marchillo K VanHecker J Andes DR In Vivo Pharmacodynamic Characterization of a Novel Antibiotic Odilorhabdins, NOSO-502 against <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> in a Murine Thigh Infection Model. Antimicrob Agents Chemother . 2018 Jul 9;
[PubMed ID: 29987156]
Andes D Kovanda L Desai A Kitt T Zhao M Walsh TJ Isavuconazole Concentration in Real-World Practice: Consistency with Results from Clinical Trials. Antimicrob Agents Chemother . 2018 Jul;62(7)
[PubMed ID: 29735569]
Van Dijck P Sjollema J Cammue BP Lagrou K Berman J d'Enfert C Andes DR Arendrup MC Brakhage AA Calderone R Cantón E Coenye T Cos P Cowen LE Edgerton M Espinel-Ingroff A Filler SG Ghannoum M Gow NAR Haas H Jabra-Rizk MA Johnson EM Lockhart SR Lopez-Ribot JL Maertens J Munro CA Nett JE Nobile CJ Pfaller MA Ramage G Sanglard D Sanguinetti M Spriet I Verweij PE Warris A Wauters J Yeaman MR Zaat SAJ Thevissen K Methodologies for <i>in vitro</i> and <i>in vivo</i> evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb Cell . 2018 Jun 14;5(7):300-326
[PubMed ID: 29992128]
Kim D Liu Y Benhamou RI Sanchez H Simón-Soro � Li Y Hwang G Fridman M Andes DR Koo H Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm. ISME J . 2018 Jun;12(6):1427-1442
[PubMed ID: 29670217]
Jaromin A Zarnowski R Piętka-Ottlik M Andes DR Gubernator J Topical delivery of ebselen encapsulated in biopolymeric nanocapsules: drug repurposing enhanced antifungal activity. Nanomedicine (Lond) . 2018 May;13(10):1139-1155
[PubMed ID: 29873597]
Dominguez E Zarnowski R Sanchez H Covelli AS Westler WM Azadi P Nett J Mitchell AP Andes DR Conservation and Divergence in the <i>Candida</i> Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control. MBio . 2018 Apr 3;9(2)
[PubMed ID: 29615504]
Park JH Craig W Marchillo K Huang DB Andes DR Identification of the <i>In Vivo</i> Pharmacokinetics and Pharmacodynamic Driver of Iclaprim. Antimicrob Agents Chemother . 2018 Apr;62(4)
[PubMed ID: 29378717]
Zhao M Lepak AJ VanScoy B Bader JC Marchillo K Vanhecker J Ambrose PG Andes DR <i>In Vivo</i> Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model. Antimicrob Agents Chemother . 2018 Apr;62(4)
[PubMed ID: 29378706]
Lepak AJ Zhao M VanScoy B Ambrose PG Andes DR Pharmacodynamics of a Long-Acting Echinocandin, CD101, in a Neutropenic Invasive-Candidiasis Murine Model Using an Extended-Interval Dosing Design. Antimicrob Agents Chemother . 2018 Feb;62(2)
[PubMed ID: 29203480]
Bader JC Bhavnani SM Andes DR Ambrose PG We can do better: a fresh look at echinocandin dosing. J Antimicrob Chemother . 2018 Jan 1;73(suppl_1):i44-i50
[PubMed ID: 29304211]
Srivastava A Sircaik S Husain F Thomas E Ror S Rastogi S Alim D Bapat P Andes DR Nobile CJ Panwar SL Distinct roles of the 7-transmembrane receptor protein Rta3 in regulating the asymmetric distribution of phosphatidylcholine across the plasma membrane and biofilm formation in Candida albicans. Cell Microbiol . 2017 Dec;19(12)
[PubMed ID: 28745020]
Rossi DCP Gleason JE Sanchez H Schatzman SS Culbertson EM Johnson CJ McNees CA Coelho C Nett JE Andes DR Cormack BP Culotta VC Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis. PLoS Pathog . 2017 Dec;13(12):e1006763
[PubMed ID: 29194441]
Schmitt-Hoffmann AH Kato K Townsend R Potchoiba MJ Hope WW Andes D Spickermann J Schneidkraut MJ Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother . 2017 Dec;61(12)
[PubMed ID: 28971866]
Desai AV Kovanda LL Hope WW Andes D Mouton JW Kowalski DL Townsend RW Mujais S Bonate PL Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi. Antimicrob Agents Chemother . 2017 Dec;61(12)
[PubMed ID: 28923872]
Lakota EA Bader JC Ong V Bartizal K Miesel L Andes DR Bhavnani SM Rubino CM Ambrose PG Lepak AJ Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters. Antimicrob Agents Chemother . 2017 Nov;61(11)
[PubMed ID: 28848022]
Andes DR Lepak AJ In vivo infection models in the pre-clinical pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents. Curr Opin Pharmacol . 2017 Oct;36:94-99
[PubMed ID: 28964956]
Revankar SG Baddley JW Chen SC Kauffman CA Slavin M Vazquez JA Seas C Morris MI Nguyen MH Shoham S Thompson GR 3rd Alexander BD Simkins J Ostrosky-Zeichner L Mullane K Alangaden G Andes DR Cornely OA Wahlers K Lockhart SR Pappas PG A Mycoses Study Group International Prospective Study of Phaeohyphomycosis: An Analysis of 99 Proven/Probable Cases. Open Forum Infect Dis . 2017 Fall;4(4):ofx200
[PubMed ID: 29766015]
Zhang F Barns K Hoffmann FM Braun DR Andes DR Bugni TS Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris. J Nat Prod . 2017 Sep 22;80(9):2551-2555
[PubMed ID: 28840714]
Ostrosky-Zeichner L Andes D The Role of In Vitro Susceptibility Testing in the Management of Candida and Aspergillus. J Infect Dis . 2017 Aug 15;216(suppl_3):S452-S457
[PubMed ID: 28911047]