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David R. Andes, MD close
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David R. Andes, MD
 

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David R. Andes, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Andes’ clinical interests include general infectious diseases, transplant infectious diseases, mycology, antimicrobial pharmacokinetics and pharmacodynamics. 

Specialties

Infectious Diseases

Travel Medicine

Clinics

University Hospital
(608) 263-0946 | (800) 323-8942 | Map
University Hospital
(608) 890-6167 | (800) 323-8942 | Map

Hospital Affiliation(s)

University Hospital
UnityPoint Health - Meriter
Veterans Hospital - Wm. S. Middleton Memorial

UW School of Medicine and Public Health

Department of Medicine

Professional Certifications and Education

Board Certification Infectious Diseases
Fellowship University of Wisconsin Hospital and Clinics, Madison, WI
Residency University of Wisconsin Hospital and Clinics, Madison, WI
Internship University of Wisconsin Hospital and Clinics, Madison, WI
Medical School University of Missouri School of Medicine, Columbia, MO

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

The overriding themes of our research programs are to advance our understanding of antibacterial and antifungal activity and drug resistance, and to identify new antimicrobial drug treatment strategies and drug targets.


PubMed Articles
Sundermann AJ Clancy CJ Pasculle AW Liu G Cumbie RB Driscoll E Ayres A Donahue L Pergam SA Abbo L Andes DR Chandrasekar P Galdys AL Hanson KE Marr KA Mayer J Mehta S Morris MI Perfect J Revankar SG Smith B Swaminathan S Thompson GR 3rd Varghese M Vazquez J Whimbey E Wingard JR Nguyen MH How Clean Is the Linen at My Hospital? The Mucorales on Unclean Linen Discovery Study of Large United States Transplant and Cancer Centers. Clin Infect Dis . 2018 Oct 9;
[PubMed ID: 30299481]
Zarnowski R Sanchez H Covelli AS Dominguez E Jaromin A Berhardt J Heiss C Azadi P Mitchell A Andes DR Candida albicans biofilm-induced vesicles confer drug resistance through matrix biogenesis. PLoS Biol . 2018 Oct 8;16(10):e2006872
[PubMed ID: 30296253]
Andes D Has the optimal therapy for invasive candidiasis now been defined? Clin Infect Dis . 2018 Oct 5;
[PubMed ID: 30289475]
Lepak AJ Zhao M Andes DR Pharmacodynamic Evaluation of Rezafungin (CD101) Against <i>Candida auris</i> in the Neutropenic Mouse Invasive Candidiasis Model. Antimicrob Agents Chemother . 2018 Sep 4;
[PubMed ID: 30181375]
Zhao M Lepak AJ Marchillo K VanHecker J Andes DR <i>In Vivo</i> Pharmacodynamic Characterization of a Novel Odilorhabdin Antibiotic, NOSO-502, against Escherichia coli and Klebsiella pneumoniae in a Murine Thigh Infection Model. Antimicrob Agents Chemother . 2018 Sep;62(9)
[PubMed ID: 29987156]
Owens RC Jr Bulik CC Andes DR Pharmacokinetics-pharmacodynamics, computer decision support technologies, and antimicrobial stewardship: the compass and rudder. Diagn Microbiol Infect Dis . 2018 Aug;91(4):371-382
[PubMed ID: 29776710]
Andes D Kovanda L Desai A Kitt T Zhao M Walsh TJ Isavuconazole Concentration in Real-World Practice: Consistency with Results from Clinical Trials. Antimicrob Agents Chemother . 2018 Jul;62(7)
[PubMed ID: 29735569]
Van Dijck P Sjollema J Cammue BP Lagrou K Berman J d'Enfert C Andes DR Arendrup MC Brakhage AA Calderone R Cantón E Coenye T Cos P Cowen LE Edgerton M Espinel-Ingroff A Filler SG Ghannoum M Gow NAR Haas H Jabra-Rizk MA Johnson EM Lockhart SR Lopez-Ribot JL Maertens J Munro CA Nett JE Nobile CJ Pfaller MA Ramage G Sanglard D Sanguinetti M Spriet I Verweij PE Warris A Wauters J Yeaman MR Zaat SAJ Thevissen K Methodologies for <i>in vitro</i> and <i>in vivo</i> evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb Cell . 2018 Jun 14;5(7):300-326
[PubMed ID: 29992128]
Kim D Liu Y Benhamou RI Sanchez H Simón-Soro � Li Y Hwang G Fridman M Andes DR Koo H Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm. ISME J . 2018 Jun;12(6):1427-1442
[PubMed ID: 29670217]
Jaromin A Zarnowski R Piętka-Ottlik M Andes DR Gubernator J Topical delivery of ebselen encapsulated in biopolymeric nanocapsules: drug repurposing enhanced antifungal activity. Nanomedicine (Lond) . 2018 May;13(10):1139-1155
[PubMed ID: 29873597]
Dominguez E Zarnowski R Sanchez H Covelli AS Westler WM Azadi P Nett J Mitchell AP Andes DR Conservation and Divergence in the <i>Candida</i> Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control. MBio . 2018 Apr 3;9(2)
[PubMed ID: 29615504]
Park JH Craig W Marchillo K Huang DB Andes DR Identification of the <i>In Vivo</i> Pharmacokinetics and Pharmacodynamic Driver of Iclaprim. Antimicrob Agents Chemother . 2018 Apr;62(4)
[PubMed ID: 29378717]
Zhao M Lepak AJ VanScoy B Bader JC Marchillo K Vanhecker J Ambrose PG Andes DR <i>In Vivo</i> Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model. Antimicrob Agents Chemother . 2018 Apr;62(4)
[PubMed ID: 29378706]
Lepak AJ Zhao M VanScoy B Ambrose PG Andes DR Pharmacodynamics of a Long-Acting Echinocandin, CD101, in a Neutropenic Invasive-Candidiasis Murine Model Using an Extended-Interval Dosing Design. Antimicrob Agents Chemother . 2018 Feb;62(2)
[PubMed ID: 29203480]
Bader JC Bhavnani SM Andes DR Ambrose PG We can do better: a fresh look at echinocandin dosing. J Antimicrob Chemother . 2018 Jan 1;73(suppl_1):i44-i50
[PubMed ID: 29304211]
Srivastava A Sircaik S Husain F Thomas E Ror S Rastogi S Alim D Bapat P Andes DR Nobile CJ Panwar SL Distinct roles of the 7-transmembrane receptor protein Rta3 in regulating the asymmetric distribution of phosphatidylcholine across the plasma membrane and biofilm formation in Candida albicans. Cell Microbiol . 2017 Dec;19(12)
[PubMed ID: 28745020]
Rossi DCP Gleason JE Sanchez H Schatzman SS Culbertson EM Johnson CJ McNees CA Coelho C Nett JE Andes DR Cormack BP Culotta VC Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis. PLoS Pathog . 2017 Dec;13(12):e1006763
[PubMed ID: 29194441]
Schmitt-Hoffmann AH Kato K Townsend R Potchoiba MJ Hope WW Andes D Spickermann J Schneidkraut MJ Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother . 2017 Dec;61(12)
[PubMed ID: 28971866]
Desai AV Kovanda LL Hope WW Andes D Mouton JW Kowalski DL Townsend RW Mujais S Bonate PL Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi. Antimicrob Agents Chemother . 2017 Dec;61(12)
[PubMed ID: 28923872]
Lakota EA Bader JC Ong V Bartizal K Miesel L Andes DR Bhavnani SM Rubino CM Ambrose PG Lepak AJ Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters. Antimicrob Agents Chemother . 2017 Nov;61(11)
[PubMed ID: 28848022]