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Dai Yamanouchi, MD, PhD

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Dai Yamanouchi, MD, PhD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Yamanouchi is certified by the Japanese Board of Surgery and is a board certified Fellow of the Japanese College of Angiology. His expertise includes treatments for aortic aneurysms, carotid disease, aortic dissection, peripheral arterial disease and other vascular disorders.


Vascular Surgery

Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm Repair


Aortic Aneursym

Aortic Aneurysm

Aortic Aneurysm Repair

Arm Angioplasty

Arteriorvenous Fistula


Balloon Angioplasty

Brachiocephalic Artery Disease

Carotid Artery Surgery

Carotid Disease

Carotid Stenosis


Dialysis Access Surgery

Endovascular Graft Repair for Abdominal Aortic Aneurysm

Endovascular Graft Repair for Aortic Aneurysm

Foot Ulcers


Laser Therapy for Veins

Limb Preservation

Limb Salvage

Limb Salvage Surgery

Lower Extremity Bypass Surgery

Mesenteric Artery Disease

Minimal Incision Phlebectomy

Minimally Invasive Abdominal Aortic Aneurysm Repair

Minimally Invasive Aortic Aneurysm Repair

Peripheral Arterial Disease

Peripheral Bypass Surgery

Radiofrequency Ablation for Vein Conditions

Renal Artery Disease

Sclerotherapy for Veins

Subclavian Artery Disease

Subclavian Vein Occlusion

Superior Vena Cava Syndrome

Thoracic Outlet Syndrome

Treatment for Spider Veins or Varicose Veins

Vascular and Endovascular Surgery

Venous Disease

Venous Stasis Disease

Visceral Angioplasty


1 S. Park Clinic
(608) 287-2100 | (888) 703-2778 | Map
Stoughton Clinic
(608) 877-2660 | | Map
UW Health at The American Center
(608) 440-6300 | (844) 607-4800 | Map
West Clinic
(608) 263-8915 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Surgery

Professional Certifications and Education


Vascular Surgery, Nagoya University Hospital, Japan

Advanced Endovascular Surgery, University of Wisconsin Hospital and Clinics, Madison, WI

Residency Gunma University Hospital, Japan
Saiseikai Maebashi Hospital, Japan
Internship Gunma University Hospital, Japan
Medical School Gunma University, Maebashi, Japan

Languages Spoken

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Yamanouchi's research interests include the pathogenesis of abdominal aortic aneurysm and restenosis after angioplasty, including balloon angioplasty and stenting. He is also devoted to the development of novel materials for vascular bypass graft and gene delivery methods to treat patients who suffer from peripheral arterial disease.

PubMed Articles
Kelly MJ Igari K Yamanouchi D Osteoclast-Like Cells in Aneurysmal Disease Exhibit an Enhanced Proteolytic Phenotype. Int J Mol Sci . 2019 Sep 21;20(19)
[PubMed ID: 31546645]
Igari K Kelly MJ Yamanouchi D Digoxin Attenuates Receptor Activation of NF-κB Ligand-Induced Osteoclastogenesis in Macrophages. J Vasc Res . 2019;56(2):55-64
[PubMed ID: 31085912]
Igari K Kelly MJ Yamanouchi D Cigarette Smoke Extract Activates Tartrate-Resistant Acid Phosphatase-Positive Macrophage. J Vasc Res . 2019;56(3):139-151
[PubMed ID: 31064000]
Tanaka T Kelly M Takei Y Yamanouchi D RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice. J Vasc Surg . 2018 Dec;68(6S):48S-59S.e1
[PubMed ID: 29685509]
Yamanouchi D Invited commentary. J Vasc Surg . 2018 Nov;68(5):1551
[PubMed ID: 30360843]
Yamanouchi D Invited commentary. J Vasc Surg . 2018 Jun;67(6):1900-1901
[PubMed ID: 29801557]
Leung AD Yamanouchi D Case report of retrograde in situ fenestration of the thoracic stent graft with reentry device in a patient with aortobronchial fistula. Medicine (Baltimore) . 2018 Jun;97(24):e11050
[PubMed ID: 29901605]
Iijima M Gombodorj N Tachibana Y Tachibana K Yokobori T Honma K Nakano T Asao T Kuwahara R Aoyama K Yasuda H Kelly M Kuwano H Yamanouchi D Development of single nanometer-sized ultrafine oxygen bubbles to overcome the hypoxia-induced resistance to radiation therapy via the suppression of hypoxia-inducible factor‑1α. Int J Oncol . 2018 Mar;52(3):679-686
[PubMed ID: 29393397]
Leung AD Yamanouchi D Osteoclastogenesis in Abdominal Aortic Aneurysms: A New Therapeutic Target. Curr Drug Targets . 2018;19(11):1233-1240
[PubMed ID: 28950811]
Kurihara C Tanaka T Yamanouchi D Hyperglycemia attenuates receptor activator of NF-κB ligand-induced macrophage activation by suppressing insulin signaling. J Surg Res . 2017 Jun 15;214:168-175
[PubMed ID: 28624040]
Tanaka T Takei Y Zaima N Moriyama T Yamanouchi D Hyperglycemia Suppresses RANKL-Induced Osteoclast Differentiation through LXRβ Expression in RAW264.7 Cells. J Nutr Sci Vitaminol (Tokyo) . 2017;63(1):28-34
[PubMed ID: 28367923]
Takei Y Tanaka T Kent KC Yamanouchi D Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms. Arterioscler Thromb Vasc Biol . 2016 Sep;36(9):1962-71
[PubMed ID: 27386936]
Wiseman JT Fernandes-Taylor S Gunter R Barnes ML Saunders RS Rathouz PJ Yamanouchi D Kent KC Inter-rater agreement and checklist validation for postoperative wound assessment using smartphone images in vascular surgery. J Vasc Surg Venous Lymphat Disord . 2016 Jul;4(3):320-328.e2
[PubMed ID: 27318052]
Tanaka T Takei Y Yamanouchi D Hyperglycemia Suppresses Calcium Phosphate-Induced Aneurysm Formation Through Inhibition of Macrophage Activation. J Am Heart Assoc . 2016 Mar 28;5(3):e003062
[PubMed ID: 27021877]
Tanaka T Moriyama T Kawamura Y Yamanouchi D Puerarin Suppresses Macrophage Activation via Antioxidant Mechanisms in a CaPO<sub>4</sub>-Induced Mouse Model of Aneurysm. J Nutr Sci Vitaminol (Tokyo) . 2016;62(6):425-431
[PubMed ID: 28202848]
Gupta PK Smith BK Yamanouchi D Case Report of Percutaneous Retrograde Transcollateral Recanalization of the Superior Mesenteric Artery via the Celiac Artery for Acute Mesenteric Ischemia. Medicine (Baltimore) . 2015 Dec;94(50):e2036
[PubMed ID: 26683911]
Gupta PK Engelbert TL Ramanan B Fang X Yamanouchi D Hoch JR Acher CW Postdischarge outcomes after endovascular abdominal aortic aneurysm repair. J Vasc Surg . 2014 Apr;59(4):903-8
[PubMed ID: 24360236]
Takayama T Yamanouchi D Aneurysmal disease: the abdominal aorta. Surg Clin North Am . 2013 Aug;93(4):877-91, viii
[PubMed ID: 23885935]
Matsumura JS Yamanouchi D Goldstein JA Pollock CW Bosiers M Schultz GA Scheinert D Rocha-Singh KJ The United States StuDy for EvalUating EndovasculaR TreAtments of Lesions in the Superficial Femoral Artery and Proximal Popliteal By usIng the Protégé EverfLex NitInol STent SYstem II (DURABILITY II). J Vasc Surg . 2013 Jul;58(1):73-83.e1
[PubMed ID: 23642924]
Yamanouchi D Oshitari T Nakamura Y Yotsukura J Asanagi K Baba T Nizawa T Kishimoto T Yonemori Y Ota S Yamamoto S Primary neuroendocrine carcinoma of ocular adnexa. Case Rep Ophthalmol Med . 2013;2013:281351
[PubMed ID: 24294530]