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Charles M. Leys, MD, MSCI close
Charles M. Leys, MD, MSCI

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Charles M. Leys, MD, MSCI Print Friendly Page

Chief, Division of Pediatric Surgery
Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Leys he is Director of pediatric minimally-invasive surgery at American Family Children’s Hospital. His practice emphasizes minimally-invasive approaches to numerous pediatric and newborn surgical diseases, including congenital anomalies, thoracic disorders, chest wall deformities, tumors and gastrointestinal disorders such as inflammatory bowel disease and gastroesophageal reflux. His training includes a two-year oncology research fellowship at Vanderbilt University and he has also earned a Masters in Clinical Investigation degree.


Pediatric General Surgery

Anorectal Malformations


Biliary Atresia


Chronic Constipation


Colonic Atresia

Congenital Cystic Adenomatoid Malformation (CCAM)

Congenital Diaphragmatic Hernia (CDH)

Correction of Chest Wall Deformities

Correction of Cloaca and Cloacal Exstrophy

Crohn's Disease

Cystic Hygroma/Lymphatic Malformations

Cystic Lung Lesions

Duodenal Atresia

Esophageal Atresia (EA)

Failure to Thrive

Gastroenterology and Hepatology

Gastroesophageal Reflux Disease


Hepatic Tumor

Hereditary Spherocytosis

Hiatal Hernia

Hirschsprung's Disease




Hypospadias Repair

Ileal Atresia

Imperforate Anus Surgery

Inguinal Hernia


Jejunal Atresia


Meckel's Diverticulum

Minimally Invasive Pediatric and Neonatal Surgery

Necrotizing Enterocolitis



Pectus Carinatum

Pectus Excavatum

Pediatric Hematology and Oncology

Pilonidal Sinus/Cyst/Abscess

Pulmonary Sequestration

Pyloric Stenosis

Sacrococcygeal Teratoma

Sickle Cell Anemia

Skin Lesions/Cysts

Splenic Sequestration

Tracheoesophageal Atresia

Ulcerative Colitis

Umbilical Hernia

Vascular Anomalies


Wilm's Tumor


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American Family Children's Hospital
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Hospital Affiliation(s)

American Family Children's Hospital
UnityPoint Health - Meriter

UW School of Medicine and Public Health

Department of Surgery

Professional Certifications and Education

Board Certification Pediatric Surgery

Pediatric Surgery, Children's Mercy Hospital, Kansas City, MO

Residency Vanderbilt University Medical Center, Nashville, TN
Medical School University of Wisconsin School of Medicine and Public Health (formerly UW Medical School), Madison, WI

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.

Dr. Leys' research interests include prospective clinical trials and quality improvement.

PubMed Articles
Gonzalez DO Lawrence AE Cooper JN Sola R Jr Garvey E Weber BC St Peter SD Ostlie DJ Kohler JE Leys CM Deans KJ Minneci PC Can ultrasound reliably identify complicated appendicitis in children? J Surg Res . 2018 Sep;229:76-81
[PubMed ID: 29937019]
Lal DR Gadepalli SK Downard CD Ostlie DJ Minneci PC Swedler RM Chelius TH Cassidy L Rapp CT Billmire D Bruch S Burns RC Deans KJ Fallat ME Fraser JD Grabowski J Hebel F Helmrath MA Hirschl RB Kabre R Kohler J Landman MP Leys CM Mak GZ Raque J Rymeski B Saito JM St Peter SD von Allmen D Warner BW Sato TT Midwest Pediatric Surgery Consortium. Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg . 2018 Jul;53(7):1267-1272
[PubMed ID: 28599967]
Zens TJ Rogers AP Riedesel EL Leys CM Ostlie DJ Woods MA Gill KG The cost effectiveness and utility of a "quick MRI" for the evaluation of intra-abdominal abscess after acute appendicitis in the pediatric patient population. J Pediatr Surg . 2018 Jun;53(6):1168-1174
[PubMed ID: 29673611]
Minneci PC Kabre RS Mak GZ Halleran DR Cooper JN Afrazi A Calkins CM Downard CD Ehrlich P Fraser J Gadepalli SK Helmrath MA Kohler JE Landisch R Landman MP Lee C Leys CM Lodwick DL Mon R McClure B Rymeski B Saito JM Sato TT St Peter SD Wood R Levitt MA Deans KJ Midwest Pediatric Surgery Consortium. Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium. J Pediatr Surg . 2018 Jun;53(6):1163-1167
[PubMed ID: 29602552]
Notrica DM Sayrs LW Bhatia A Letton RW Alder A St Peter S Ponsky TA Eubanks JW 3rd Lawson KA Ostlie DJ Tuggle DW Garcia NM Maxson RT Leys C Greenwell C The incidence of delayed splenic bleeding in pediatric blunt trauma. J Pediatr Surg . 2018 Feb;53(2):339-343
[PubMed ID: 29079311]
Fallon SC Langer JC St Peter SD Tsao K Kellagher CM Lal DR Whitehouse JS Diesen DL Rollins MD Pontarelli E Malek MM Iqbal CW Upperman JS Leys CM Wulkan ML Hill SJ Blakely ML Kane TD Wesson DE Congenital H-type tracheoesophageal fistula: A multicenter review of outcomes in a rare disease. J Pediatr Surg . 2017 Nov;52(11):1711-1714
[PubMed ID: 28528013]
Elsaid MY Gill KG Gosain A Nichol PF Leys CM Buehler D Leith CP Patel NJ Synchronous Presentation of Renal Cell Carcinoma and Hodgkin Lymphoma in an Adolescent. J Pediatr Hematol Oncol . 2017 Oct;39(7):e399-e402
[PubMed ID: 28092312]
Lal DR Gadepalli SK Downard CD Ostlie DJ Minneci PC Swedler RM Chelius T Cassidy L Rapp CT Deans KJ Fallat ME Finnell SME Helmrath MA Hirschl RB Kabre RS Leys CM Mak G Raque J Rescorla FJ Saito JM St Peter SD von Allmen D Warner BW Sato TT Midwest Pediatric Surgery Consortium. Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula. J Pediatr Surg . 2017 Aug;52(8):1245-1251
[PubMed ID: 27993359]
Hirschl RB Minneci P Gadepalli S Saito JM Askegard-Giesmann J Deans K Downard C Fallat M Finnell M Helmrath M Kabre R Lal D Leys C Mak G Ostlie D Rescorla F Sato T St Peter S von Allmen D Warner B MidWest Pediatric Surgery Consortium (MWPSC). Development of a multi-institutional clinical research consortium for pediatric surgery. J Pediatr Surg . 2017 Jul;52(7):1084-1088
[PubMed ID: 28081853]
Magoteaux SR Notrica DM Langlais CS Linnaus ME Raines AR Letton RW Alder AC Greenwell C Eubanks JW Lawson KA Garcia NM St Peter SD Ostlie DJ Leys CM Bhatia A Maxson RT Tuggle DW Ponsky TA Hypotension and the need for transfusion in pediatric blunt spleen and liver injury: An ATOMAC+ prospective study. J Pediatr Surg . 2017 Jun;52(6):979-983
[PubMed ID: 28363471]
Linnaus ME Langlais CS Garcia NM Alder AC Eubanks JW 3rd Maxson RT Letton RW Ponsky TA St Peter SD Leys C Bhatia A Ostlie DJ Tuggle DW Lawson KA Raines AR Notrica DM Failure of nonoperative management of pediatric blunt liver and spleen injuries: A prospective Arizona-Texas-Oklahoma-Memphis-Arkansas Consortium study. J Trauma Acute Care Surg . 2017 Apr;82(4):672-679
[PubMed ID: 28099382]
Linnaus ME Notrica DM Langlais CS St Peter SD Leys CM Ostlie DJ Maxson RT Ponsky T Tuggle DW Eubanks JW 3rd Bhatia A Alder AC Greenwell C Garcia NM Lawson KA Motghare P Letton RW Prospective validation of the shock index pediatric-adjusted (SIPA) in blunt liver and spleen trauma: An ATOMAC+ study. J Pediatr Surg . 2017 Feb;52(2):340-344
[PubMed ID: 27717564]
Vaughan N Tweed J Greenwell C Notrica DM Langlais CS Peter SD Leys CM Ostlie DJ Maxson RT Ponsky T Tuggle DW Eubanks JW 3rd Bhatia A Greenwell C Garcia NM Lawson KA Motghare P Letton RW Alder AC The impact of morbid obesity on solid organ injury in children using the ATOMAC protocol at a pediatric level I trauma center. J Pediatr Surg . 2017 Feb;52(2):345-348
[PubMed ID: 27707653]
Rogers AP Zens TJ Leys CM Nichol PF Ostlie DJ A call for a standardized definition of perforated appendicitis. J Pediatr Surg . 2017 Jan;52(1):89-92
[PubMed ID: 27884453]
Acher CW Ostlie DJ Leys CM Struckmeyer S Parker M Nichol PF Long-Term Outcomes of Patients with Tracheoesophageal Fistula/Esophageal Atresia: Survey Results from Tracheoesophageal Fistula/Esophageal Atresia Online Communities. Eur J Pediatr Surg . 2016 Dec;26(6):476-480
[PubMed ID: 26692337]
Rogers AP Zens TJ Kohler JE Le HD Nichol PF Leys CM A Single Institution Review of Initial Application of a 5-mm Stapler. J Laparoendosc Adv Surg Tech A . 2016 Aug;26(8):660-2
[PubMed ID: 27398952]
Boomer LA Cooper JN Anandalwar S Fallon SC Ostlie D Leys CM Rangel S Mattei P Sharp SW St Peter SD Rodriguez JR Kenney B Besner GE Deans KJ Minneci PC Delaying Appendectomy Does Not Lead to Higher Rates of Surgical Site Infections: A Multi-institutional Analysis of Children With Appendicitis. Ann Surg . 2016 Jul;264(1):164-8
[PubMed ID: 26692077]
Decharun K Leys CM West KW Finnell SM Prophylactic Antibiotics for Prevention of Cholangitis in Patients With Biliary Atresia Status Post-Kasai Portoenterostomy: A Systematic Review. Clin Pediatr (Phila) . 2016 Jan;55(1):66-72
[PubMed ID: 26183324]
Gonzalez KW Dalton BG Snyder CL Leys CM St Peter SD Ostlie DJ The anatomic findings during operative exploration for non-palpable testes: A prospective evaluation. J Pediatr Surg . 2016 Jan;51(1):128-30
[PubMed ID: 26563527]
Ostlie DJ Leys CM Fraser JD Snyder CL St Peter SD Laparoscopic Orchiopexy Requiring Vascular Division: A Randomized Study Comparing the Primary and Two-Stage Approaches. J Laparoendosc Adv Surg Tech A . 2015 Jun;25(6):536-9
[PubMed ID: 25974325]