Melanoma and skin cancer: Prevention, early detection keys to fighting melanoma

At the UW Health | Carbone Cancer Center, we provide expert care for melanoma and skin cancer. If untreated, these cancers can spread to other organs in your body. When caught early, they can be treated and cured.

In partnership with UW dermatologists, our melanoma and skin cancer program specializes in diagnosing skin cancer early. We also excel at treating advanced skin cancer.

You have an increased risk of getting melanoma or other forms of skin cancers from spending too much time in the sun. Excess UV radiation can cause normal skin cells to become abnormal. The damaged skin cells can then grow out of control and attack nearby tissues.

Your skin tone and family history might also put you at risk for melanoma. Risk factors include:

• Fair skin

• Family history of melanoma

• Atypical moles

• History of blistering sunburns

A change in the color, shape or size of a mole can be a sign of melanoma. Melanomas often appear:

• At least ¼ inch or larger

• Brown or black

• Flat with uneven edges

• Irregular or asymmetrical in shape

A melanoma can be itchy, sore and bleed. Alternatively, you might not experience any symptoms.

Moles can often appear on the upper back of both men and women. They are also common on women's legs.  

Diagnosing and staging melanoma

Your doctor checks your skin. If your care team suspects a melanoma, we perform a biopsy. We take a small sample of tissue from the suspected melanoma, and a pathologist studies the tissue to look for cancer cells.

If the biopsy shows melanoma, you will likely be referred to see a surgeon. You might need more tests to see if the cancer has spread. These include imaging scans, such as CT, MRI or PET.

Your care team will find the best treatment for your melanoma. For early-stage melanoma, surgery to remove the cancer cells might be the only treatment you need. Surgery also could include a sentinel lymph node biopsy to determine if melanoma has spread to the lymph nodes.

Other treatments might be necessary if the melanoma has spread to other parts of the body or is advanced. These include:

• Immunotherapy

• Targeted therapy

• Radiation therapy

The skin cancer team at the UW Health | Carbone Cancer Center meets regularly in a specialized Tumor Board to discuss complex melanoma and other advanced skin cancer cases. Bringing together an expert team from across different programs — including oncology, ophthalmology and plastic surgery, among others — ensures patients receive the best possible care.

Offering cutting edge treatments

In 2024, UW Health | Carbone Cancer Center became one of about a dozen cancer centers across the United States — and the only one located within a 500-mile radius of Madison, Wis. — authorized to administer the new Hepzato treatment for patients with uveal melanoma that has spread to the liver.

Learn more about the treatment

Take steps to prevent melanoma

You can prevent melanoma by protecting yourself whenever you are in the sun, no matter your skin tone. Follow these tips:

• Minimize sun exposure between 10 a.m.–4 p.m.

• Check your skin often for odd marks, moles or sores that will not heal

• Do not sunbathe or use tanning salons

• Get regular skin checks from a dermatologist

• Reapply sunscreen every two hours when you are outside

• Use extra sun protection when near the water, at high elevation or in tropical climates

• Use sunscreen with an SPF of at least 30 during times of sun exposure

• Use sunscreen that blocks UVA and UVB radiation

• Wear sun-protective clothing outside, like a hat to shade your scalp and face 

Clinical trials: Advancing melanoma care with research

Our melanoma doctors and scientists work to improve skin cancer care for you. Our Melanoma Disease-Oriented Team studies new diagnostic tools and treatments and provides multispecialty care for patients. We also lead clinical trials.

Search our clinical trials

If you are experiencing life with melanoma, you are not alone. Find encouragement from other patients who have been through similar challenges.

The UW Health melanoma care team includes specialists in dermatology, medical oncology, otolaryngology, plastic surgery, radiation oncology and surgical oncology.

We provide specialized care for melanoma at UW Health | Carbone Cancer Center clinics in Madison, Wis., and Rockford, Ill.

Learn more about melanoma and how you can stay safe in the sun.