Chemotherapy for Bladder Cancer
Chemotherapy and Bladder Cancer
Chemotherapy plays a major role in the treatment of metastatic bladder cancer that has spread to the lymph nodes, lungs, liver and other parts of the body. In patients whose bladder cancer has metastatsized at diagnosis, chemotherapy is the frontline treatment.
For metastatic bladder cancer we use a combination of two drugs: gemcitabine and cisplatinum. This combination is less toxic than MVAC (methotrexate, vinblastine, adriamycin and cisplatin) with similar response rates. Both chemotherapies have an average survival rate of 14 months.
Chemotherapy and Surgery
Chemotherapy is also used in conjunction with surgery for patients who are at high risk for metastasis. Data suggest that bladder tumors that have invaded the muscle wall and have the potential to spread can benefit from chemotherapy before surgery (neoadjuvant therapy).