The Small Molecule Screening and Synthesis Facility (SMSSF) Shared Resource provides UW Carbone Cancer Center (UWCCC) members, other UW faculty and students, and scientists from other universities and companies with fee-for-service access to early stage drug discovery infrastructure, expert staff and services. These services include:
SMSSF provides access to instrumentation and data analysis for image-based cellular assays in 96-well or 384-well plates. The EVOS® FL Auto Cell Imaging System has automated stage movement, focus, and exposure. Use it for cell based assays involving fluorescence or bright field. Fee-for-service image analysis using ImageJ is also available at SMSSF.
These activities foster collaborative drug discovery research between chemists, biologists and physician scientists that leads to the identification of new small molecules that inhibit cancer phenotypes in cellular or animal models and that can be further developed for clinical evaluation in human cancer patients. SMSSF services also are available for drug discovery in all other therapeutic areas.
Through the SMSSF, UW faculty may access the services of Dr.
Learn more about the Small Molecule Screening and Synthesis Facility's Scientific Accomplishments.
Funding received from the UWCCC Cancer Center Support Grant (CCSG) for published research, including the use of UWCCC Shared Resources to generate or analyze data, or conduct clinical trials, needs to reference the UWCCC. See Acknowledging UWCCC in Publications, Posters and Presentations.
View the UW Drug Discovery and Development website for more information on other UW-Madison laboratory facilities that provide state-of-the-art instrumentation and expert scientific staff.