American Family Children's Hospital

Preclinical Analytic Services

The Cancer Pharmacology Core provides preclinical therapeutics analysis by generating tumor-bearing animals and conducting evaluations in these model systems. The Cancer Pharmacology Core generates xenograft mouse models from a variety of human cell lines, including A549 lung carcinoma, MDA-MB-231 breast carcinoma and UM-SCC-74A and 74B head and neck squamous cell carcinoma.


The Cancer Pharmacology Core provides a complete set of services that include consultation regarding experimental design, tumor cell growth in culture and generation of tumors in mice, administration of experimental agents, monitoring of tumor burden and response to therapy, maximally tolerated dose determinations and PK and tissue distribution.


Please email Joan Rettig to request any of these analytical services.