Preclinical Analytic Services
The 3P Lab provides preclinical therapeutics analysis by generating tumor-bearing animals and conducting evaluations in these model systems. The 3P Lab generates xenograft mouse models from a variety of human cell lines, including A549 lung carcinoma, MDA-MB-231 breast carcinoma and UM-SCC-74A and 74B head and neck squamous cell carcinoma.
The 3P Lab provides a complete set of services that include consultation regarding experimental design; tumor cell growth in culture and generation of tumors in mice; administration of experimental agents; monitoring of tumor burden and response to therapy; maximally tolerated dose determinations; and PK and tissue distribution.
Please email Jill Kolesar to request any of these analytical services.