To accomplish its mission, members of the Chemoprevention Program and their inter-programmatic collaborators pursue basic laboratory studies of neoplastic development and potential intervention agents and perform clinical trials to expand mechanistic understanding and assess the potential clinical viability of novel chemopreventive agents. These objectives are met through the following specific aims.
Modeling and Targets
- Study neoplastic development and progression and associated targets for intervention
- Development of model systems that allow efficient and accurate study of neoplasic progression and directed interventions
- Identification of new targets for chemoprevention agent development
- Identify and study new agents for chemoprevention drug development
- Design and perform cancer chemoprevention clinical trials