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American Family Children's Hospital

Published Virtual Colonoscopy Research Articles

UW Health radiologists have written or contributed to the following published research articles regarding virtual colonoscopy:
Pickhardt PJ, Hassan C, Laghi A, Zullo A, Kim DH, Iafrate F, Morini S. Small and diminutive polyps detected at screening CT colonography: a decision analysis for referral. AJR (in press)
Taylor SA, Tam E, Greenhalgh R, Sahni V, Ilangovan R, Burling D, Zhang J, Bassett P, Pickhardt PJ, Halligan S. CT colonography and computer assisted detection: Effect of false positives on reader specificity and reading efficiency in a low prevalence screening population. Radiology (accepted for publication)
Pickhardt PJ, Lee AD, Taylor AJ, Michel SJ, Winter TC, Shadid A, Meiners RJ, Chase PJ, Hinshaw JL, Williams JG, Prout TM, Husain SH, Kim DH. Primary 2D versus primary 3D polyp detection at screening CT colonography. AJR (in press)
Deshpande KK, Summers RM, van Uitert RL, Franaszek M, Brown L, Dwyer AJ, Fletcher JG, Choi JR, Pickhardt PJ.  Quality assessment for CT colonography:
validation of automated measurement of colonic distention and residual fluid. AJR (in press)
Hanson ME, Pickhardt PJ, Kim DH, Pfau PR. Anatomic factors predictive of incomplete colonoscopy based on findings at CT colonography. AJR (in press)
Kim DH, Pickhardt PJ, Taylor AJ, MeniasCO. Imaging evaluation of complications at optical colonoscopy. Curr Probl Diagn Radiol (in press)
Pickhardt PJ, Kim DH, MeniasCO, Gopal DV, Arluk GM, Heise CP. Evaluation of submucosal lesions of the large intestine, part I: neoplastic causes. Radiographics 2007 (in press)
Pickhardt PJ, Kim DH, MeniasCO, Gopal DV, Arluk GM, Heise CP. Evaluation of submucosal lesions of the large intestine, part II: non-neoplastic causes. Radiographics 2007 (in press)
Michel SJ, Pickhardt PJ, Kim DH, Taylor AJ. Effect of colonic distention technique on superiority of supine versus prone views at screening CT colonography. Clin Imaging (in press).
Petrick N, Haider M, Summers RM, Yeshwant S, Brown L, Iuliano EM, Louie A, Choi JR, Pickhardt PJ. CT colonography with computer-aided detection as a second reader: an observer performance study. Radiology (in press)
Pickhardt PJ. Screening CT colonography: how I do it. AJR (in press)
Pickhardt PJ. Colonic preparation at CT colonography: understanding the relative advantages and disadvantages of a non-cathartic approach. Mayo Clin Proc 2007;82:659-661 
Kim DH, Pickhardt PJ, Hoff G, Kay CL. CT colonography for colorectal screening. Endoscopy 2007;39:545-549
Pickhardt PJ. Polyp detection at CT colonography: inadequate primary 3D endoluminal reference standard precludes meaningful comparison (letter). Radiology 2007;244:316-317
Kim DH, Pickhardt PJ. CT colonography: pertinent issues for the colorectal surgeon. Semin Colon Rectal Surg 2007;18:88-95
Pickhardt PJ, Hassan C, Laghi A, Zullo A, Kim DH, Morini S. Cost-effectiveness of colorectal cancer screening with CT colonography: The impact of not reporting diminutive lesions. Cancer 2007;109:2213-2221
Pickhardt PJ, Kim DH. CT colonography (virtual colonoscopy): a practical approach for population screening. Radiol Clin North Am 2007;45:361-375
Huang A, Roy DA, Summers RM, Franaszek M, Petrick N, Choi JR, Pickhardt PJ. Tenia coli-based circumferential localization system for CT colonography: feasibility study. Radiology 2007;243:551-560
Kim DH, Pickhardt PJ, Taylor AJ. Characteristics of advanced adenomas detected at CT colonography screening: implications for appropriate polyp size thresholds for polypectomy versus surveillance. AJR 2007;188:940-944
Pickhardt PJ. The natural history of colorectal polyps and masses: rediscovered truths from the barium enema era. AJR 2007;188:619-621
Vijan S, Hwang I, Inadomi J, Wong RKH, Choi JR, Napierkowski J, Koff JM, Pickhardt PJ. The cost-effectiveness of CT colonography in screening for colorectal neoplasia. Am J Gastroenterol 2007;102:380-390
Kim DH, Pickhardt PJ, Hinshaw JL, Taylor AJ, Mukherjee R, Pfau PR. Prospective blinded trial comparing 45-ml and 90-ml doses of oral sodium phosphate for bowel preparation prior to CT colonography. J Comput Assist Tomogr 2007;31:53-58
O’Connor SD, Summers RM, Yao J, Pickhardt PJ, Choi JR. CT Colonography with computer-aided polyp detection: volume and attenuation thresholds to reduce ileocecal valve false positives. Radiology 2006;241:426-432
Pickhardt PJ. Utilization of the double-contrast barium enema in the early era of screening CT colonography (letter). AJR 2006;187:W661
Pickhardt PJ, Kim DH, Taylor AJ, Gopal DV, Weber SM, Heise CP. Extracolonic tumors of the gastrointestinal tract detected incidentally at screening CT colonography. Dis Colon Rectum 2006;50:1-8
Pickhardt PJ, Taylor AJ, Kim DH, Reichelderfer M, Gopal DV, Pfau PR. Screening for colorectal neoplasia with CT colonography: initial experience from the first year of coverage by third-party payers. Radiology 2006;241:417-425
Yeshwant SC, Summers RM, Yao J, Brickman D, Choi JR, Pickhardt PJ. Linear and volumetric measurement of polyps in CT colonography. Radiology 2006;241:802-811
Sanford MS, Pickhardt PJ. Diagnostic performance of primary 3-dimensional computed tomography colonography in the setting of colonic diverticular disease. Clin Gastroenterol Hepatol 2006;4:1039-1047
Pickhardt PJ, Lehman VT, Winter TC, Taylor AJ. Comparison of polyp volume versus linear size measurement at CT colonography: implications for noninvasive surveillance of unresected colorectal lesions. AJR 2006;186:1605-1610
Shinners TJ, Pickhardt PJ, Taylor AJ, Jones DA, Olsen CH. Patient-controlled room air insufflation versus automated carbon dioxide delivery for CT colonography. AJR 2006;186:1491-1496
Pickhardt PJ, Taylor AJ, Gopal DV. Surface visualization at 3D endoluminal CT colonography: degree of coverage and implications for polyp detection. Gastroenterology 2006;130:1582-1587
Pickhardt PJ. The incidence of colonic perforation at CT colonography: review of the existing data and the implications for screening of asymptomatic adults. Radiology 2006;239:313-316
Lee AD, Pickhardt PJ, Gopal DV, Taylor AJ. Venous malformations mimicking multiple mucosal polyps at screening CT colonography. AJR 2006;186:1113-1115
Franaszek M, Summers RM, Pickhardt PJ, Choi JR. Hybrid segmentation of colon filled with air and opacified fluid for CT colonography. IEEE Trans Med Imaging 2006;25:358-368
Pickhardt PJ, Taylor AJ. Extracolonic findings identified in asymptomatic adults at screening CT colonography. AJR 2006;186:718-728
Pickhardt PJ. High-magnification chromoscopic colonoscopy: caution needs to be exercised before changing screening policy (reply). AJR 2006;186:577-578
Prout TM, Taylor AJ, Pickhardt PJ. Inverted appendiceal stumps simulating large pedunculated polyps at screening CT colonography. AJR 2006;186:535-538
O’Connor SD, Summers RM, Yao J, Choi JR, Pickhardt PJ. Oral contrast adherence to polyps on CT colonography.  J Comput Assist Tomogr 2006;30:51-57
Pickhardt PJ. Virtual colonoscopy: issues related to primary screening. Eur Radiol 2005;15[Suppl 4]:D133-D137
Summers RM, Yao J, Pickhardt PJ, Franaszek M, Bitter I, Brickman D, Krishna V, Choi JR. Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. Gastroenterology 2005;129:1832-1844
Pickhardt PJ, Lee AD, McFarland EG, Taylor AJ.   Linear polyp measurement at CT colonography: in vitro and in vivo comparison of two-dimensional and three-dimensional displays. Radiology 2005;236:872-878
Pickhardt PJ. Virtual colonoscopy for primary screening: the future is now. Minerva Chir 2005;60:139-150
Zalis ME, Barish MA, Choi JR, Dachman AH, Fenlon HM, Ferrucci JT, Glick SN, Laghi A, Macari M, McFarland EG, Morrin MM, Pickhardt PJ, Soto J, Yee J, for the Working Group on Virtual Colonoscopy. CT Colonography Reporting and Data System: A Consensus Proposal. Radiology 2005;236:3-9
Pickhardt PJ, Choi JR. Adenomatous polyp obscured by small-caliber rectal catheter at CT colonography: a rare diagnostic pitfall. AJR 2005;184:1581-1583
Pickhardt PJ, Taylor AJ, Johnson GL, Fleming LA, Jones DA, Pfau PR, Reichelderfer M. Building a CT colonography program: necessary ingredients for reimbursement and clinical success. Radiology 2005;235:17-20
Pickhardt PJ, Halberg R, Taylor AJ, Durkee BY, Fine J, Lee FT, Weichert JP. Micro-computed tomography colonography for polyp detection in an in vivo mouse tumor model. Proc Natl Acad Sci 2005;102:3419-3422
Iordanescu G, Pickhardt PJ, Choi JR, SummersRM. Automated seed placement for colon segementation in CT colonography. Acad Radiol 2005;12:182-190
Pickhardt PJ. CT colonography (virtual colonoscopy) for primary colorectal screening: challenges facing clinical implementation. Abdom Imaging 2005;30:1-4   
Summers RM, FranaszekM, Miller MT, PickhardtPJ, ChoiJR, Schindler WR. Computer-aided detection of polyps in oral contrast-enhanced CT colonography. AJR 2005;184:105-108
Pickhardt PJ. CT colonography without catharsis: the ultimate study or useful additional option? (letter) Gastroenterology 2005;128:521-522
Pickhardt PJ. Limitations of virtual colonoscopy (reply). Ann Int Med 2005; 142:155
Pickhardt PJ. Differential diagnosis of polypoid lesions seen at CT colonography (virtual colonoscopy). Radiographics 2004;24:1535-1559
Pickhardt PJ, Choi JR, Nugent PA, Schindler WR. The effect of diagnostic confidence on the probability of optical colonoscopic confirmation for potential polyps detected at CT colonography: prospective assessment in 1339 asymptomatic adults. AJR 2004;183:1661-1665
Pickhardt PJ, Nugent PA, Mysliwiec PA, Choi JR, Schindler WR. Location of adenomas missed at optical colonoscopy. Ann Intern Med 2004;141:352-359
Pickhardt PJ, Nugent PA, Choi JR, Schindler WR. Flat colorectal lesions in asymptomatic adults: implications for screening with CT virtual colonoscopy. AJR 2004;183:1343-1347
Pickhardt PJ, Choi JR, Hwang I, Schindler WR. Nonadenomatous polyps at CT colonography: prevalence, size distribution, and detection rates. Radiology 2004;232:784-790
Pickhardt PJ. Translucency rendering in 3D endoluminal CT colonography: A useful tool for increasing polyp specificity and decreasing interpretation time. AJR 2004;183:429-436
Pickhardt PJ. Virtual colonoscopy for primary colorectal screening: the road to implementation. Decisions in Imaging Economics 2004;17:27-30
Pickhardt PJ. Virtual colonoscopy (letter). JAMA 2004;292:431
Ferrucci J, Barish M, Choi R, Dachman A, Fenlon H, Glick S, Laghi A, Macari M, Morrin M, Paulson E, Pickhardt PJ, Soto J, Yee J, Zalis M; Working Group on Virtual Colonoscopy. Virtual colonoscopy (letter). JAMA 2004;292:431-432
Pickhardt PJ. Virtual colonoscopy - finally a credible contender (comment). Gastroenterology 2004;126:1911-1912
Pickhardt PJ. Virtual colonoscopy to screen for colorectal cancer (reply). N Engl J Med 2004;350:1148-1150
Pickhardt PJ, Choi JR, Hwang I, Butler JA, Puckett ML, Hildebrandt HA, Wong RK, Nugent PA, Mysliwiec PA, Schindler WR. CT virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 2003;349:2191-2200 
Pickhardt PJ. By-patient performance characteristics for CT colonography: importance of polyp size threshold data (letter). Radiology 2003; 229:291-293
Pickhardt PJ. Three-dimensional endoluminal CT colonography (virtual colonoscopy): comparison of three commercially available systems. AJR 2003;181:1599-1606
Pickhardt PJ, Choi JR. Electronic cleansing and stool tagging in CT colonography: advantages and pitfalls encountered with primary three-dimensional evaluation. AJR 2003;181:799-805