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Movement Disorders Clinical Trials

UW Health's Movement Disorders Program, based at UW Hospital and Clinics in Madison, Wisconsin, provides a breadth of expertise and a range of services unmatched in the region.
 
The list below discusses parameters of current clinical trials offered through UW Health's movement disorders program.
 
 

Sillay Lab Institutional Review Board Approved Research

 
Study contact (for all): Call (608) 262-6223.
  1. Impulse Control Disorders in Parkinson's Disease Patients Treated with Deep Brain Stimulation

    Parkinson's disease is a debilitating neurological disease. A common treatment for Parkinson's disease, dopamine replacement therapy, is known to cause impulse control disorders such as pathological gambling, hypersexuality and excessive shopping in a small proportion of patients. Currently research suggests that deep brain stimulation (DBS), another treatment for Parkinson's disease, may alter impulse control disorders in Parkinson's disease patients. In this study, Parkinson's disease patients who have undergone DBS will be tested with and without their brain stimulator delivering active stimulation to determine the effects of DBS impulse control disorders.
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  3. Effects of Deep Brain Stimulation on Decision-Making for Eye Movements in Patients with Parkinson's Disease

    Parkinson's disease is traditionally considered a disorder of movement; however, certain patients also often experience cognitive symptoms. It has been suggested that DBS may alter performance on cognitive testing. This work seeks to extend recent investigations in humans and non-human primates, to humans with Parkinson’s disease being treated with deep-brain stimulation.
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  5. Deep Brain Stimulation Device Battery Life Assessment: Medtronic Soletra and Kinetra

    This investigation is a nine-year retroactive chart review of all deep-brain stimulation cases performed at the University of Wisconsin Hospital and Clinics. We hope to uncover trends in stimulation parameters, impulse generator battery characteristics and electrode variations in order to provide insight into the intricacies of deep-brain stimulation technology. This research may provide clinicians with novel guidance and methodology for deep-brain stimulation therapy.