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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: IL28b

Test Code(s): IL28B / HCIL28B

CPT Code(s): 81479

Methodology: Real-Time PCR followed by Melting Point Analysis

Clinical Significance: Identification of two polymorphisms, rs12979860 and rs8099917, involved in response to interferon treatment for Hepatitis C virus infection.

Days Performed: Once a week.

Turnaround Time: Stat: Not available stat.
Routine: 10 days.

Specimen Requirements

Specimen: Blood

Collection Instructions: Please contact UWHC Test Referral office at (608) 262-6388 prior to sample collection.
For UWHC - ordering source must fill out the Referral Screening Flow Sheet prior to specimen collection.
For UWMF - ordering source must fill out the UWMF Genetic Lab Request prior to specimen collection.

Collection Container: Preferred: Lavender top

Collection Volume: Preferred: 4 mL
Pediatrics: 2 mL

Sample Analyzed: Whole Blood

Volume Required: Preferred: 2 mL
Pediatrics: 1.2 mL

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220) immediately. Refrigerate specimen if not delivered immediately. Specimen must be received within 3 days of collection date.

Stability: Ambient: 7 days
Refrigerated: 3 weeks
Frozen: Not acceptable


A written interpretive report is provided by the laboratory.

Additional Information:

The performance characteristics of this test were validated by UWHC Clinical Laboratories. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test; however, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. The UWHC Clinical Laboratories is authorized under Clinical Laboratory Improvement Amendments (CLIA) to perform high-complexity testing.


A professional fee is associated with this test.

interleukin 28 b

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