UW Hospital and Clinics Lab Test Directory
| Test Name: |
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Cyclic Citrullinated Peptide Ab, IgG
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| Test Code(s): |
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CCPIGG / XCCP
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| CPT Code(s): |
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86200
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| Methodology: |
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Quantitative Enzyme Immunoassay
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| Clinical Significance: |
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Studies have shown that detection of antibodies to CCP may predict the eventual development into RA when found in undifferentiated arthritis and is a marker of erosive disease in RA. The sensitivity of anti-CCP has been shown to be comparable to RF(50-75%) with a higher specificity(90-95%).
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| Days Performed: |
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Mon-Fri, dayshift - day varies.
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| Turnaround Time: |
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Stat: Not available stat.
Routine: 5 - 7 working days.
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Specimen Requirements
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| Specimen: |
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Blood
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| Patient Preparation: |
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None
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| Collection Container: |
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Preferred: Red top
Also Acceptable:
Red cap with yellow ring (SST)
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| Collection Volume: |
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Preferred: 3 mL
Pediatrics: 1 mL
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| Sample Analyzed: |
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Serum
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| Volume Required: |
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Preferred: 1 mL
Pediatrics: 0.3 mL
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| Specimen Processing: |
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Centrifuge. Transfer cell free serum to plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from UWHC Satellite lab or outreach location.
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| Unacceptable Criteria: |
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Serum is microbially contaminated, heat-treated, grossly hemolyzed, lipemic, turbid or has added azide or other preservatives
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| Stability: |
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Ambient: 48 hours
Refrigerated: 14 days
Frozen: 3 months at -20° C or lower. Note: Avoid repeat freeze and thaw.
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Interpretation
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Reference Interval:
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0 days and up: 0-19 Units
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0-19 Units
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Negative |
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20-39 Units
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Weak Positive |
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40-59 Units
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Moderately Positive |
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60 or more Units
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Strongly Positive |
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Anti Citrullinated Antibody
Anti Citrulline
Anti-CCP (Cyclic Citrullinated Peptide)
Anti-Citrullinated Ab
Anti-Citrullinated Antibody
Anti-Citrulline
Anti-Citrulline Antibody
Anti-Cyclic Citrullinated Peptide (CCP)
CCP (Cyclic Citrullinated Peptide)
Citrullinated Ab
Citrullinated Antibody
Cyclic Citrullinated Peptide Antibodies
CCP3
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