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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: EBV Ab to Viral Capsid Ag, IgM

Test Code(s): EBVVCM / XEBVP2

CPT Code(s): 86665

Methodology: ELISA

Clinical Significance: The intent of the test system together with other clinical information is to aid in the determination of immune status, and/or aid in the diagnosis of EBV.

Days Performed: Once a week.

Turnaround Time: Stat: Not available stat.
Routine: Up to 4 days

Specimen Requirements

Specimen: Blood

Patient Preparation: None

Collection Instructions: None

Collection Container: Preferred: Red cap with yellow ring (SST)
Also Acceptable: Red top

Collection Volume: Preferred: 1 mL
Pediatrics: 1 mL

Sample Analyzed: Serum

Volume Required: Preferred: 0.5 mL
Pediatrics: 0.3 mL

Specimen Processing: Centrifuge.  Transfer cell-free serum to plastic vial.  Refrigerate.

Specimen Transport: Transport specimen to the laboratory. Transport with coolant pack if coming from satellite or outreach location.

Unacceptable Criteria: Grossly hemolyzed/ lipemic, heat-treated serum, microbially contaminated and serum containing heavily-visible particulate.

Stability: Ambient: 8 hours
Refrigerated: 7 days
Frozen: 3 months at 20C or greater


Negative: No detectable IgM antibodies to EBV-VCA.  This indicates patient has no current infection with EBV and is presumed to be susceptible to a primary infection.
Equivocal: Immune status cannot be determined.  If clinically warranted, a second sample should be taken 7 - 21 days after the first.
Positive: Reactive for IgM antibodies to EBV-VCA, indicating a current or reactivated infection with EBV-VCA. 


All equivocal test results will be repeated within two working days.

Epstein-Barr Virus
Anti EBV Serology
E. B. (Epstein-Barr) Virus
EBV (Epstein-Barr Virus)
Epstein Barr Virus
Epstein-Barr Virus AB
VCA (Viral Capsid Antigen) IgM
EBV VCA (Viral Capsid Antigen) IgM

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