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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: HLA DP Locus

Test Code(s): DPBS/HCDPB1S (if Pre-Tx) , DPBB/ HCDPB1B (if Post-Tx)

CPT Code(s): 81376

Test Description: Test Component:

Low-to-mid level resolution HLA Class II DPB and DPA.

Methodology: Reverse SSO detected by Luminex xMAP (Multi-Analyte Profiling)

Clinical Significance: HLA class II DPB and DPA low-to-mid level resolution typing typically used to match donor and recipients or to determine clinical relevance of recipient antibodies to donor HLA typing for organ transplantation.  Also may be used to identify the presence of HLA class II alleles associated with some diseases (specify allele or disease under investigation in the request to assure proper interpretation).

Days Performed: Mon-Fri, dayshift by appointment only. Call 263-8815 (option 3) before collection.

Turnaround Time: Stat: Not available stat.
Routine: 5 working days.

Specimen Requirements

Specimen: Blood

Patient Preparation: No transfusions (RBC, WBC, Platelets) within 24 hours prior to collection.

Collection Container: Preferred: Lavender top
Also Acceptable: Yellow top(with ACD-A/B anticoagulant)

Collection Volume: Preferred: 4 mL
Pediatrics: 1 mL

Volume Required: Preferred: 4 mL
Pediatrics: 1 mL

Specimen Transport: Transport whole blood specimen at room temperature or refrigerated to UWHC Core Laboratory (B4/220).

Stability: Ambient: 7 days
Refrigerated: 3 weeks
Frozen: Not acceptable


A written interpretive report will be provided.

Additional Information:

This test was developed and its performance characteristics determined by this laboratory.  It has not been cleared or approved by the US Food and Drug Administration.  The FDA has determined that such clearance or approval is not necessary.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.  This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88) as qualified to perform high complexity clinical laboratory testing.

class II class 2 hla typing dpb dqa dp

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