| Test Name: |
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FISH- MYC/ IgH Fusion, t(8;14)(q24;q32)
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| Test Code(s): |
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881F65 / HC881F65
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| CPT Code(s): |
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88271x2, 88275
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| Methodology: |
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Fluorescence In Situ Hybridization (FISH)
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| Clinical Significance: |
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To detect the presence of specific fusions of chromosomes associated with Burkitt lymphoma. Aids in diagnosis of hematologic disorders and for monitoring disease after treatment or bone marrow transplant.
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| Testing Site: |
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Testing will be sent to an approved reference laboratory.
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| Days Performed: |
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Mon-Sat.
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| Turnaround Time: |
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Routine: 3 - 5 days.
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Specimen Requirements
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| Specimen: |
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Blood or bone marrow
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| Collection Instructions: |
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Blood or bone marrow must be received and processed by WSLH within 24 hours of collection. Specimen must be received in UWHC Core Laboratory (B4/220) on Monday-Friday only.
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| Collection Container: |
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Preferred: Green top (with sodium heparin anticoagulant)
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| Collection Volume: |
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Preferred: 1-2 mL blood or 0.5-1.0 mL bone marrow
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| Sample Analyzed: |
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Whole Blood or Bone Marrow
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220) at room temperature. Transport with coolant pack during hot weather (>85°F).
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| Unacceptable Criteria: |
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Bone marrow/blood that is clotted or hemolyzed
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| Stability: |
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Ambient: 24 hours
Refrigerated: Not acceptable
Frozen: Not acceptable
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Interpretation
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Interpretation provided with results.
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| Test Limitations: |
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Failure to identify an abnormal clone by FISH does not rule out the presence of other abnormalities in the specimen.
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| Additional Information: |
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If FISH assay is not performed in conjunction with chromosome analysis there is an additional charge for processing the specimen
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