UW Hospital and Clinics Lab Test Directory
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Monoclonal Protein Quantitation, Urine, 24 Hour
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| Test Code(s): |
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ULCT / HCULCT
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| CPT Code(s): |
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84166, 84156
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| Test Description: |
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Test Component: Urine protein electrophoresis and a quantitative urine protein.
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| Methodology: |
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Gel Electrophoresis
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| Clinical Significance: |
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Urine protein electrophoresis is used to quantitate monoclonal light chain bands previously identified by urine immunofixation.
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| Days Performed: |
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Mon-Fri, dayshift - day varies.
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| Turnaround Time: |
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Stat: Not available stat.
Routine: 3 working days.
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Specimen Requirements
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| Specimen: |
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24 hour timed urine
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| Collection Instructions: |
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No preservative.
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| Collection Container: |
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Preferred: 24 hour urine container
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| Collection Volume: |
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Preferred: Entire collection
Pediatrics: Entire collection
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| Sample Analyzed: |
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Urine aliquot
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| Volume Required: |
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Preferred: 10 mL
Pediatrics: 10 mL
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| Specimen Processing: |
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Refrigerate specimen.
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| Specimen Transport: |
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Transport entire collection to UWHC Core Laboratory (B4/220) at close of collection.
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| Outreach Specimen Transport: |
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Send aliquot from a well-mixed 24 hour collection in a sterile container with a coolant pack.
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| Unacceptable Criteria: |
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Random urine collections.
Urines with preservatives.
Urines with bloody supernatants are acceptable but not desirable.
Urines with no previously identified monoclonal proteins.
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| Stability: |
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Ambient: Not acceptable
Refrigerated: 1 week
Frozen: 3 months for concentrated sample
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Interpretation
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A written interpretive report with the scan is issued as a separate report.
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| Test Limitations: |
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The total urine protein method may underestimate the tubular and light chain protein fractions causing an underestimate in the semi-quantitative protein values reported by electrophoresis. The percent relationship of light chain proteins to tubular proteins and the ability to detect light chains is not affected.
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| Additional Information: |
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A professional fee is associated with this test.
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UPEP,ULCT,urine protein electrophoresis
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