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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Fetal Fibronectin

Test Code(s): FTLFIB / GM2782

CPT Code(s): 82731

Methodology: Adeza Biomedical TLi Solid-Phase Immunosorbent System

Clinical Significance: Useful in the detection of fetal fibronectin in cervicovaginal secretions.  Between 24 to 34 completed weeks gestation, this is associated with preterm delivery in symptomatic and asymptomatic pregnant women.

Testing Site: Testing will be sent to an approved reference laboratory.

Days Performed: Mon-Sun.


Specimen Requirements

Specimen: Cervicovaginal secretion

Patient Preparation: Patient should not be tested within 24 hours after sexual intercourse because semen and/or sperm present may cause a false-positive result.

Collection Instructions: 1.  Obtain prior to digital cervical examination or vaginal
     probe ultrasound examination as manipulation of the
     cervix may cause release of fetal fibronectin.
2.  Do not use lubricants, soaps, or disinfectant (e.g.
     K-YŽ Jelly lubricant, BetadineŽ disinfectant,
     hexacholorophene) on speculum or cervicovaginal
     secretions as they may interfere with test.

Collection Container: Preferred: Adeza Specimen Collection Kit

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
Refrigerated specimen must be received by performing laboratory within 72 hours of collection. Specimens must be sent via taxi as soon as received in lab.

Stability: Ambient: Not acceptable
Refrigerated: 72 hours
Frozen: Not acceptable


Interpretation

Results reported as positive or negative with interpretation.

Test Limitations:

Moderate or gross vaginal bleeding may interfere with test.

FFN

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