| Test Name: |
|
Immunoglobulin E
|
|
|
|
|
|
|
| Test Code(s): |
|
IGE
|
|
|
|
|
|
|
| CPT Code(s): |
|
82785
|
|
|
|
|
|
|
| Methodology: |
|
Immunonephelometry
|
|
|
|
|
|
|
| Clinical Significance: |
|
IgE is responsible for the clinical picture observed in immediate-type allergies. In allergic diseases such as atopic dermatitis or asthma, the serum IgE concentrations generally correlate with the intensity of exposure to the allergen and with the intensity of allergic symptoms.
|
|
|
|
|
|
|
| Days Performed: |
|
Daily.
|
|
|
|
|
|
|
| Turnaround Time: |
|
Stat: 1 hour.
Routine: 4 hours.
|
|
|
|
Specimen Requirements
|
|
|
|
| Specimen: |
|
Blood
|
|
|
|
|
|
|
| Collection Container: |
|
Preferred: Red cap with yellow ring (SST)
Also Acceptable:
Red top
|
|
|
|
|
|
|
| Collection Volume: |
|
Preferred: 3 mL
Pediatrics: 1 mL
|
|
|
|
|
|
|
| Sample Analyzed: |
|
Serum
|
|
|
|
|
|
|
| Volume Required: |
|
Preferred: 1 mL
Pediatrics: 0.3 mL
|
|
|
|
|
|
|
| Specimen Processing: |
|
Centrifuge within 2 hours and transfer cell-free serum to plastic vial. Refrigerate.
|
|
|
|
|
|
|
| Specimen Transport: |
|
Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from UWHC Satellite lab locations.
|
|
|
|
|
|
|
| Outreach Specimen Transport: |
|
Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach locations.
|
|
|
|
|
|
|
| Unacceptable Criteria: |
|
Grossly hemolyzed specimens are unacceptable.
|
|
|
|
|
|
|
| Stability: |
|
Ambient: Not acceptable
Refrigerated: 7 days
Frozen: 3 months at -20°C or below
|
|
|
|
Interpretation
|
|
|
|
|
Reference Interval:
|
|
| Age: |
IU/mL |
| 1-5 years: |
0-59 |
| 6-9 years: |
0-89 |
| 10-15 years: |
0-199 |
| 16 years and up: |
0-99 |
|
|
|
|
|
|
|
| Test Limitations: |
|
High Rheumatoid factor level
|
|
|
|
|
|
|