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UW Health SMPH
American Family Children's Hospital

UW Hospital and Clinics Lab Test Directory

Test Name: Smooth Muscle Ab

Test Code(s): ASMA / XSMOO

CPT Code(s): 86255

Methodology: Indirect Fluorescence

Clinical Significance: Associated with chronic active hepatitis. Note that many other chronic immune diseases or liver infections are associated with anti-smooth muscle antibodies, typically in low titer.

Days Performed: Mon-Fri, dayshift.

Turnaround Time: Stat: Not available stat.
Routine: 2 working days.


Specimen Requirements

Specimen: Blood

Collection Container: Preferred: Red top
Also Acceptable: Red cap with yellow ring (SST)

Collection Volume: Preferred: 3 mL
Pediatrics: 1 mL

Sample Analyzed: Serum

Volume Required: Preferred: 1 mL
Pediatrics: 0.2 mL

Specimen Processing: Centrifuge. Transfer cell-free serum to plastic vial.  Refrigerate.

Specimen Transport: Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from UWHC Satellite lab locations or outreach location.

Unacceptable Criteria: Grossly hemolyzed and lipemic specimens are not recommended.

Stability: Ambient: Not acceptable
Refrigerated: 7 days
Frozen: No limit at -20C; avoid repeat freeze and thaw.


Interpretation

Normal Smooth Muscle Ab (0 days and up):  Negative

 

Smooth Muscle Antibody, Anti-Smooth Muscle Antibodies

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