| Test Name: |
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CA 19-9 (Cancer Antigen-GI)
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| Test Code(s): |
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CA199 / XCA199
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| CPT Code(s): |
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86301
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| Methodology: |
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Chemiluminescent Immunoassay
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| Request Form: |
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UWHC Laboratory Request Form (UWH 1289220, 4004202); Write in test if not on form.
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| Days Performed: |
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Mon-Fri, dayshift.
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| Turnaround Time: |
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Routine: Next working day.
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Specimen Requirements
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| Specimen: |
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Blood
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| Collection Container: |
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Preferred: Red cap with yellow ring (SST)
Also Acceptable:
Red top
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| Collection Volume: |
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Preferred: 1 mL
Pediatrics: 0.5 mL
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| Sample Analyzed: |
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Serum
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| Volume Required: |
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Preferred: 0.5 mL
Pediatrics: 0.15 mL
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| Specimen Processing: |
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Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.
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| Specimen Transport: |
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Transport specimen to UWHC Core Laboratory (B4/220). Transport with coolant pack if coming from outreach location.
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| Stability: |
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Ambient: 8 hours
Refrigerated: 48 hours
Frozen: okay
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Interpretation
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Reference Interval:
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0 - 35 U/mL
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| Test Limitations: |
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The Siemens ADVIA Centaur method is used. Results obtained with different assay methods or kits cannot be used interchangeably.
Patients must possess the ability to express the Lewis blood group antigen or they will be unable to produce the CA 19-9 antigen even in the presence of proven malignancy.
Results may be affected if patient has developed heterophilic antibodies due to exposure to animal based protein products.
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| Additional Information: |
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This method is indicated for the serial measurement of CA 19-9 to aid in the management of patients diagnosed with cancers of the exocrine pancreas. The ADVIA Centaur CA 19-9 assay is not indicated for screening or early detection of pancreatic cancer or as a diagnostic tool to confirm the presence or absence of malignant pancreatic disease.
A high dose hook effect is not seen up to 5,800,000 Units/mL.
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